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View article: Cardiometabolic effects of oxytocin in modeling the diabetic phenotype of chronic heart failure
Cardiometabolic effects of oxytocin in modeling the diabetic phenotype of chronic heart failure Open
Background . The combination of heart failure (HF) and type 2 diabetes mellitus (DM2T) is considered one of the most common and unfavorable duets. A promising area of modern research is the development of translational models of the diabet…
View article: Experimental and Histological Validation of Nanostructured Products Use in Maxillofacial Surgery
Experimental and Histological Validation of Nanostructured Products Use in Maxillofacial Surgery Open
The aim of the study is using experimental histological techniques to validate the beneficial potential of specific medical devices made of nanostructured titanium, and compare their effect with factorymade products currently applied in ma…
View article: Choice of an experimental model and modeling method in the study of the pathogenesis and methods of treatment of age-related macular degeneration (review)
Choice of an experimental model and modeling method in the study of the pathogenesis and methods of treatment of age-related macular degeneration (review) Open
Background . Experimental modeling of various pathological processes in the organ of vision is an integral part of both fundamental and applied research. For a deeper understanding of the pathogenesis of age-related macular degeneration (A…
View article: The state and prospects of traditional and innovative methods in the teaching of histology, cytology and embryology in a medical university (debatable aspects)
The state and prospects of traditional and innovative methods in the teaching of histology, cytology and embryology in a medical university (debatable aspects) Open
The work is devoted to the analysis of the role, significance and effectiveness of traditional and innovative teaching methods in the study of histology, cytology and embryology in a medical college. Years of experience have shown that the…
View article: Role of Melatonin in Human Eye Physiology and Its Implications for Ophthalmic Diseases Treatment (Review)
Role of Melatonin in Human Eye Physiology and Its Implications for Ophthalmic Diseases Treatment (Review) Open
Melatonin is a hormone of the epiphysis and a regulator of circadian rhythms of living organisms, which affects a number of important physiological processes. Melatonin synthesis has also been found in other organs, in particular in variou…
View article: Stem cells and fundamental problems of classical histology
Stem cells and fundamental problems of classical histology Open
The paper summarizes modern concepts of stem cells, considers their classification, the importance for the fundamental purposes of cell biology and clinical medicine, and shows the contradictions between the concepts of classical histology…
View article: MORPHOLOGICAL AND ELECTRON MICROSCOPIC CHARACTERISTICS OF THE SKIN AND MUCOUS MEMBRANE AT VARIOUS STAGES OF COMBINED TREATMENT OF ORAL CANCER
MORPHOLOGICAL AND ELECTRON MICROSCOPIC CHARACTERISTICS OF THE SKIN AND MUCOUS MEMBRANE AT VARIOUS STAGES OF COMBINED TREATMENT OF ORAL CANCER Open
Using electron microscopic studies, the structural and functional reorganization of the neck skin and mucous membrane in patients with malignant tumors of the oral cavity at various stages of combined treatment is presented. Significant vi…
View article: Features of Reparative Histogenesis in Bioplastic Material Application
Features of Reparative Histogenesis in Bioplastic Material Application Open
In modern medicine, various biocompatible materials (based on biodegradable natural biopolymers – collagen, hyaluronic acid, chitin, chitosan, etc.) are widely used, primarily for the purposes of reconstructive and plastic surgery. The dev…
View article: Molecular Genetic Aspects of the Optimizing Effect of Oxytocin on the Reparative Processes of Rabbit Eye Corneal Epithelial and Stromal Structures
Molecular Genetic Aspects of the Optimizing Effect of Oxytocin on the Reparative Processes of Rabbit Eye Corneal Epithelial and Stromal Structures Open
The aim of study was to determine the regenerative effect of oxytocin on the expression of PAX6, MKI67, TAB3 genes, respectively, during experimental corneal erosion. Material and methods . The study involved experimental animals divided i…
View article: Structural and Functional Reorganization of the Retina in an Experimental Simulation of Age-Related Macular Degeneration and the Melatonin Effect
Structural and Functional Reorganization of the Retina in an Experimental Simulation of Age-Related Macular Degeneration and the Melatonin Effect Open
The aim of the study was to evaluate regularities of morphological and functional reorganization of the rabbit retina in the experimental simulation of age-related macular degeneration (AMD) and the use of melatonin. Material and methods. …
View article: The Effect of Oxytocin on Reparative Histogenesis in the Periodontium and Mucous Membrane of the Airways (Experimental Study)
The Effect of Oxytocin on Reparative Histogenesis in the Periodontium and Mucous Membrane of the Airways (Experimental Study) Open
The aim of the study was to elucidate the role and significance of oxytocin in reparative histogenesis of tissues of various genesis using the example of periodontal tissues and extrapulmonary airways. Material and methods. Periodontitis a…
View article: The Structural and Functional Basis of Physiological and Reparative Regeneration of Corneal Tissues
The Structural and Functional Basis of Physiological and Reparative Regeneration of Corneal Tissues Open
The article is devoted to the review and analysis of scientific literature on physiological and reparative histogenesis in the cornea. The most vulnerable in injuries of the anterior parts of the eye is the cornea. Therefore, it is extreme…
View article: Morphological and Immunohistochemical Characteristics of Experimental Mandibular Fractures Healing Process
Morphological and Immunohistochemical Characteristics of Experimental Mandibular Fractures Healing Process Open
The aim of the study is histological assessment of the effect of oxytocin local application on mandibular fractures healing. Material and methods. The investigated material was the lower jaw in the fracture zone, fastened by the bone sutur…
View article: STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF THE THYMUS OF RATS WITH ALLOXAN DIABETES AT DIFFERENT METHODS OF TREATMENT OF DEEP PURULENT WOUNDS OF THE LOWER LIMBS
STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF THE THYMUS OF RATS WITH ALLOXAN DIABETES AT DIFFERENT METHODS OF TREATMENT OF DEEP PURULENT WOUNDS OF THE LOWER LIMBS Open
The treatment of purulent wounds in patients with diabetes mellitus is a difficult and urgent problem of the modern medicine. The disruption of the immune status is one of the pathogenetic links of the cascade of pathological processes wit…
View article: Gender particulars of morphological phenotypes of the right atrial appendage myocardium in patients with chronic heart failure who underwent an open heart surgery
Gender particulars of morphological phenotypes of the right atrial appendage myocardium in patients with chronic heart failure who underwent an open heart surgery Open
Background: For many decades, women in all age groups have a high risk of mortality and perioperative complications of cardiac surgery (CS), with its cause being unclear until now. Preoperative prediction of cardiovascular complications (C…
View article: THE USE OF COMPOSITE MATERIAL LITAR TO CORRECT LIVER RESIDUAL CAVITIES
THE USE OF COMPOSITE MATERIAL LITAR TO CORRECT LIVER RESIDUAL CAVITIES Open
Aim. Experimental and histological study the possibility of using composite material “LitAr” for sealing and elimination of residual liver cavities in combination with oxytocin including in case of infection. Material and Methods. All stud…
View article: The role of telocytes in myocardial remodeling and the development of cardiovascular complications in patients with chronic heart failure after coronary artery bypass grafting
The role of telocytes in myocardial remodeling and the development of cardiovascular complications in patients with chronic heart failure after coronary artery bypass grafting Open
The intercellular network Tc with secreted regulatory factors and microvesicles is an important structural and functional link of the myocardium. The decrease in BD Tc has a significant effect on the remodeling and regenerative potential o…
View article: Role of telocytes in the heart in health and diseases
Role of telocytes in the heart in health and diseases Open
This review summarizes the data available in the literature on the development, structure, and function of telocytes (TCs) and their role in the heart in health and diseases. At the present time, TCs have been found in many organs of mamma…
View article: Prognostic Value of Melatonin Level, Structural and Functional Changes of the Myocardium in the Development of Complications in Patients With Heart Failure who Underwent Coronary Artery Bypass Grafting: the Possibilities of Pharmacological Cardioprotection
Prognostic Value of Melatonin Level, Structural and Functional Changes of the Myocardium in the Development of Complications in Patients With Heart Failure who Underwent Coronary Artery Bypass Grafting: the Possibilities of Pharmacological Cardioprotection Open
Preoperative evaluation of the level of melatonin sulfate, apoptosis markers, and comorbid load can serve as prognostic factors of complicated course of the postoperative period after CABG in patients with CHF. The combination of perindopr…
View article: USE OF MILIACYLЕ AND PHYSICAL METHODS IN THE TREATMENT OF TROPHIC ULCERS OF LOWER LIMBS
USE OF MILIACYLЕ AND PHYSICAL METHODS IN THE TREATMENT OF TROPHIC ULCERS OF LOWER LIMBS Open
The clinical studies included 340 patients with trophic ulcers in lower limbs. It is for the first time that the therapeutic efficacy of local application of Miliacyle combined with magnetolasertherapy has been studied in 124 patients with…
View article: Method of closing the residual cavity with composite material “LitAr” in combination with an antibiotic for chronic pleural empyema and features of reparative histogenesis
Method of closing the residual cavity with composite material “LitAr” in combination with an antibiotic for chronic pleural empyema and features of reparative histogenesis Open
Our research examines the features of reparative histogenesis in liquidation of rigid residual cavity
\nin chronic pleural empyema by means of a composite material. An experiment was conducted using
\n30 laboratory rats to model limited ch…
View article: PECULIARITIES OF EARLY PROCESS COURSE IN RATS AGAINST THE BACKGROUND OF ALLOXAN DIABETES WHEN USING DIFFERENT METHODS OF LOCAL THERAPY
PECULIARITIES OF EARLY PROCESS COURSE IN RATS AGAINST THE BACKGROUND OF ALLOXAN DIABETES WHEN USING DIFFERENT METHODS OF LOCAL THERAPY Open
Aim. The aim of the study was to determine the clinical efficiency of local use of “Miliacyl” and EHF-therapy for the treatment of purulent wounds against the background of alloxan diabetes in experimental conditions. Materials and methods…