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View article: Supplementary Figure 1B from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis
Supplementary Figure 1B from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis Open
Supplementary Figure 1B. Effect of Frondanol A5 treatment on colon tumor (CT) cell proliferation
View article: Data from The Epidermal Growth Factor Receptor Inhibitor Gefitinib Prevents the Progression of Pancreatic Lesions to Carcinoma in a Conditional LSL-Kras<sup>G12D/+</sup> Transgenic Mouse Model
Data from The Epidermal Growth Factor Receptor Inhibitor Gefitinib Prevents the Progression of Pancreatic Lesions to Carcinoma in a Conditional LSL-Kras<sup>G12D/+</sup> Transgenic Mouse Model Open
Pancreatic ductal adenocarcinoma (PDAC) is the most common pancreatic malignancy with a dismal prognosis. Developing novel strategies to prevent or delay pancreatic cancer is currently of intense interest. The chemopreventive efficacy of g…
View article: Supplementary Figure 1B from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis
Supplementary Figure 1B from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis Open
Supplementary Figure 1B. Effect of Frondanol A5 treatment on colon tumor (CT) cell proliferation
View article: Supplementary Table 1 from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling
Supplementary Table 1 from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling Open
Supplementary Table 1. List of primers used for real-time PCR analysis
View article: Supplementary Figure 2 from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling
Supplementary Figure 2 from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling Open
Supplementary Figure 2. Western Immunoblotting for c-Myc, p21 and ODC in MiaPaCa cells
View article: Supplementary Figure 1 from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling
Supplementary Figure 1 from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling Open
Supplementary Figure 1. Immunohistochemistry of Ki67, cyclinD1, Rb and p16
View article: SupplemMaterials and Methodsentary data from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis
SupplemMaterials and Methodsentary data from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis Open
Materials and Methods
View article: Data from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis
Data from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis Open
Sea cucumbers are a source of antibacterial, anti-inflammatory, and anticancer compounds. We show that sea cucumber extract Frondanol A5 is capable of enhancing innate immune responses and inhibiting intestinal tumors in APCMin/+ mice. APC…
View article: Supplementary Figure 1A from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis
Supplementary Figure 1A from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis Open
Supplementary Figure 1A. Effect of Frondanol A5 treatment on small intestine polyps (SIPs) cell proliferation
View article: Supplementary Figure1C from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis
Supplementary Figure1C from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis Open
Supplementary Figure 1C. Proliferative index in SIPs and CTs from control and treated groups
View article: Supplementary Figure 2 from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling
Supplementary Figure 2 from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling Open
Supplementary Figure 2. Western Immunoblotting for c-Myc, p21 and ODC in MiaPaCa cells
View article: Data from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling
Data from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling Open
Ornithine decarboxylase (ODC) is the key rate-limiting enzyme in the polyamine synthesis pathway and it is overexpressed in a variety of cancers. We found that polyamine synthesis and modulation of ODC signaling occurs at early stages of p…
View article: Data from The Epidermal Growth Factor Receptor Inhibitor Gefitinib Prevents the Progression of Pancreatic Lesions to Carcinoma in a Conditional LSL-Kras<sup>G12D/+</sup> Transgenic Mouse Model
Data from The Epidermal Growth Factor Receptor Inhibitor Gefitinib Prevents the Progression of Pancreatic Lesions to Carcinoma in a Conditional LSL-Kras<sup>G12D/+</sup> Transgenic Mouse Model Open
Pancreatic ductal adenocarcinoma (PDAC) is the most common pancreatic malignancy with a dismal prognosis. Developing novel strategies to prevent or delay pancreatic cancer is currently of intense interest. The chemopreventive efficacy of g…
View article: Data from Raloxifene and Antiestrogenic Gonadorelin Inhibits Intestinal Tumorigenesis by Modulating Immune Cells and Decreasing Stem-like Cells
Data from Raloxifene and Antiestrogenic Gonadorelin Inhibits Intestinal Tumorigenesis by Modulating Immune Cells and Decreasing Stem-like Cells Open
Studies suggest that estrogen plays a contributing role in colorectal cancer. This project examined the preventive effects of raloxifene, a selective estrogen receptor modulator (SERM), and gonadorelin, an antiestrogenic drug, in female Ap…
View article: Supplementary Figure 1A from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis
Supplementary Figure 1A from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis Open
Supplementary Figure 1A. Effect of Frondanol A5 treatment on small intestine polyps (SIPs) cell proliferation
View article: Supplementary Figure 2B from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis
Supplementary Figure 2B from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis Open
Supplementary Figure 2B. CD163 protein expression in the control and Frondanol A5-treated small intestinal tumors
View article: Supplementary Figure Legends from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis
Supplementary Figure Legends from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis Open
Supplementary Figure Legends
View article: Data from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling
Data from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling Open
Ornithine decarboxylase (ODC) is the key rate-limiting enzyme in the polyamine synthesis pathway and it is overexpressed in a variety of cancers. We found that polyamine synthesis and modulation of ODC signaling occurs at early stages of p…
View article: Supplementary Table 1 from Raloxifene and Antiestrogenic Gonadorelin Inhibits Intestinal Tumorigenesis by Modulating Immune Cells and Decreasing Stem-like Cells
Supplementary Table 1 from Raloxifene and Antiestrogenic Gonadorelin Inhibits Intestinal Tumorigenesis by Modulating Immune Cells and Decreasing Stem-like Cells Open
PDF file - 61K, Primer sequences and PCR conditions for Lgr5, EpCAM, CD44, CD24, GAPDH, 5-LOX, mPGES-1, beta-catenin and cyclin D1.
View article: Supplementary Figure Legends from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling
Supplementary Figure Legends from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling Open
Supplementary Figure Legends
View article: Data from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis
Data from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis Open
Sea cucumbers are a source of antibacterial, anti-inflammatory, and anticancer compounds. We show that sea cucumber extract Frondanol A5 is capable of enhancing innate immune responses and inhibiting intestinal tumors in APCMin/+ mice. APC…
View article: Supplementary table 1 from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis
Supplementary table 1 from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis Open
Supplementary table 1 : Primers and PCR conditions
View article: Supplementary Figure2A from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis
Supplementary Figure2A from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis Open
Supplementary Figure 2A. CD163 protein expression in the control and Frondanol A5-treated colon
View article: Supplementary Table 1 from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling
Supplementary Table 1 from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling Open
Supplementary Table 1. List of primers used for real-time PCR analysis
View article: Supplementary Figure Legends from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis
Supplementary Figure Legends from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis Open
Supplementary Figure Legends
View article: Supplementary Figure2A from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis
Supplementary Figure2A from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis Open
Supplementary Figure 2A. CD163 protein expression in the control and Frondanol A5-treated colon
View article: Supplementary table 1 from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis
Supplementary table 1 from Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis Open
Supplementary table 1 : Primers and PCR conditions
View article: Data from Targeting mTOR and p53 Signaling Inhibits Muscle Invasive Bladder Cancer <i>In Vivo</i>
Data from Targeting mTOR and p53 Signaling Inhibits Muscle Invasive Bladder Cancer <i>In Vivo</i> Open
Urothelial tumors, accompanied by mutations of the tumor suppressor protein TP53 and dysregulation of mTOR signaling, are frequently associated with aggressive growth and invasiveness. We investigated whether targeting these two pathways w…
View article: Supplementary Figure 3 from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling
Supplementary Figure 3 from Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling Open
Supplementary Figure 3. Schematic representation of effect of DFMO on ODC pathway