Explanipedia

Applicability of regenerative oligodendrocyte precursor cell optic nerve transplantation in rat model of demyelinating disease Open

Itay Lotan, Benjamin Johnston, Shuhei Nishiyama, Jin Myoung Seok, Amy E. Wright , et al. · 2025

Cell-based therapies, particularly transplanted human oligodendrocyte progenitor cells (OPCs), are being explored for neuroprotection and remyelination in demyelinating diseases of the central nervous system (CNS). In this study, we invest…

Diaphragmatic pacing after cervical spinal cord injury due to gunshot wound: a 14-year institutional experience Open

Collin M. Labak, Eric Z. Herring, Elliot Crooks, Stanley Bazarek, Gabriel A. Smith , et al. · 2025

Purpose High cervical spinal cord injury (SCI) due to gunshot wound (GSW) represents an extremely devastating injury class not only due to quadriplegia, but also the high incidence of chronic mechanical ventilation (MV) due to injury to th…

Diaphragmatic Pacing after Cervical Spinal Cord Injury due to Gunshot Wound: A 14- year Institutional Experience Open

Collin M. Labak, Eric Z. Herring, Elliot Crooks, Stanley Bazarek, Gabriel A. Smith , et al. · 2025

Purpose High cervical spinal cord injury (SCI) due to gunshot wound (GSW) represents an extremely devastating injury class not only due to quadriplegia, but also the high incidence of chronic mechanical ventilation (MV) due to injury to th…

Established and novel quantitative electromyographic techniques with potential for planning nerve transfer surgery: a pilot study Open

Ross Mandeville, Art Eleanore, J. Luk, Benjamin Johnston, Reiner Henson B See , et al. · 2025

We introduce a novel quantitative electromyography technique, stimulation-free concentric needle-based motor unit number estimation, which could potentially aid surgical planning in the management of peripheral nerve injury. The ability to…

Nerve transfer for restoration of lower motor neuron-lesioned bladder, urethral and anal sphincter function. Part 4: Effectiveness of the motor reinnervation Open

Ekta Tiwari, Danielle S. Porreca, Alan S. Braverman, Lewis Holt-Bright, Nagat Frara , et al. · 2024

This data supports the use of nerve transfer techniques for the restoration of bladder function.

Supinator to Posterior Interosseous Nerve Transfer for Recovery of Hand Opening in the Tetraplegic Patient: A Case Series Open

Stanley Bazarek, Margaret Sten, Jasmine A. Thum, Ross Mandeville, G. Magee , et al. · 2024

BACKGROUND AND OBJECTIVES: Cervical spinal cord injury results in devastating loss of function. Nerve transfers can restore functional use of the hand, the highest priority function in this population to gain independence. Transfer of radi…

Stimulation-Free Concentric-Needle Motor Unit Number Estimate – a potential new biomarker for Nerve Health Open

Merle Göben, Reiner Henson B See, Carl Froilan D. Leochico, Austin Birmingham, Art Eleanore , et al. · 2024

Axillary to Radial Nerve Transfer for Recovery of Elbow Extension After Spinal Cord Injury Open

Stanley Bazarek, Jasmine A. Thum, Margaret Sten, G. Magee, Ross Mandeville , et al. · 2023

BACKGROUND AND OBJECTIVES: Cervical spinal cord injuries (SCI) result in severe loss of function and independence. Nerve transfers have become a powerful method for restoring upper extremity function, the most critical missing function des…

Selective Tibial Neurotomy for Spastic Equinovarus Foot: Operative Technique Open

Jasmine A. Thum, Stanley Bazarek, Margaret Sten, Gabriel Friedman, Ross Mandeville , et al. · 2023

BACKGROUND AND OBJECTIVES: Spastic equinovarus foot (SEF) is a common complication of stroke and other upper motor neuron injuries. It is characterized by a plantigrade and inverted foot, often with toe curling, causing significant disabil…

Nerve transfer for restoration of lower motor neuron-lesioned bladder, urethral, and anal sphincter function in a dog model. Part 3. nicotinic receptor characterization Open

Nagat Frara, Mary F. Barbe, Dania Giaddui, Danielle S. Porreca, Alan S. Braverman , et al. · 2023

Very little is known about the physiological role of nicotinic receptors in canine bladders, although functional nicotinic receptors have been reported in bladders of many species. Utilizing in vitro methods, we evaluated nicotinic recepto…

A scoping review of current and emerging techniques for evaluation of peripheral nerve health, degeneration and regeneration: part 2, non-invasive imaging Open

Ross Mandeville, Swati Deshmukh, Ek T. Tan, Viksit Kumar, Benjamin Sanchez , et al. · 2023

Peripheral neuroregenerative research and therapeutic options are expanding exponentially. With this expansion comes an increasing need to reliably evaluate and quantify nerve health. Valid and responsive measures of the nerve status are e…

A scoping review of current and emerging techniques for evaluation of peripheral nerve health, degeneration, and regeneration: part 1, neurophysiology Open

Ross Mandeville, Benjamin Sanchez, Benjamin R. Johnston, Stanley Bazarek, Jasmine A. Thum , et al. · 2023

Peripheral neuroregeneration research and therapeutic options are expanding exponentially. With this expansion comes an increasing need to reliably evaluate and quantify nerve health. Valid and responsive measures that can serve as biomark…

Restoring bladder function using motor and sensory nerve transfers: a cadaveric feasibility study Open

Benjamin R. Johnston, Stanley Bazarek, Margaret Sten, Brian S. McIntyre, Noam Fine , et al. · 2022

OBJECTIVE Bladder dysfunction after nerve injury has a variable presentation, and extent of injury determines whether the bladder is spastic or atonic. The authors have proposed a series of 3 nerve transfers for functional innervation of t…

Clinical potential of tension-lengthening strategies during nerve repair Open

SameerB Shah, Stanley Bazarek, JustinM Brown · 2021

A (very) brief history of tension in nerve repair: Successful nerve repair is achieved by conveying as many axons successfully to their targets as possible. Typically, this is best achieved through a direct end-to-end repair under minimal …

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