Stanley L. Marks
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View article: Evaluation of Veterinary Prescription of Gastroprotectants in Dogs in Spain
Evaluation of Veterinary Prescription of Gastroprotectants in Dogs in Spain Open
The overprescription of gastroprotectants, in particular acid suppressants in dogs, is of increasing concern in veterinary medicine. There have been specific guidelines published to document the appropriate use of this class of drugs; howe…
View article: Simplified Meal Bolus Strategies with Control-IQ+ Automated Insulin Delivery Are Safe and Effective in Adults with Type 2 Diabetes
Simplified Meal Bolus Strategies with Control-IQ+ Automated Insulin Delivery Are Safe and Effective in Adults with Type 2 Diabetes Open
Objective: To characterize simplified meal bolus strategies in adults with insulin-treated type 2 diabetes using automated insulin delivery (AID). Research Design and Methods: In the 2IQP study, a 13-week randomized, controlled trial compa…
View article: Subclinical gastrointestinal mucosal lesions occur in dogs with intrahepatic portosystemic shunts independent of percutaneous transvenous coil embolization
Subclinical gastrointestinal mucosal lesions occur in dogs with intrahepatic portosystemic shunts independent of percutaneous transvenous coil embolization Open
OBJECTIVE To determine the prevalence and severity of gastrointestinal mucosal lesions in dogs with intrahepatic portosystemic shunts (IHPSS), and to compare the prevalence and severity of gastrointestinal mucosal lesions in dogs with IHPS…
View article: Feline dystrophin-deficient muscular dystrophy misdiagnosed as <i>Toxoplasma</i> myositis
Feline dystrophin-deficient muscular dystrophy misdiagnosed as <i>Toxoplasma</i> myositis Open
Case summary A 6-month-old male entire domestic shorthair cat presented for presumptive Toxoplasma myopathy that was non-responsive to antiprotozoal therapy. Clinical features included marked macroglossia, dysphagia, regurgitation, truncal…
View article: Prevalence and appropriateness of omeprazole prescription in dogs at a veterinary teaching hospital before and after the publication of the ACVIM consensus statement on the rational administration of gastrointestinal protectants
Prevalence and appropriateness of omeprazole prescription in dogs at a veterinary teaching hospital before and after the publication of the ACVIM consensus statement on the rational administration of gastrointestinal protectants Open
Introduction Overprescribing of acid suppressants is a common phenomenon in human and small animal patients, leading to potential deleterious gastrointestinal (GI) and non-GI consequences. The impact of consensus statements on veterinary p…
View article: Evaluating acidic gastroesophageal reflux with wireless <scp>pH</scp> monitoring in <scp>French</scp> bulldogs with sliding hiatal herniation
Evaluating acidic gastroesophageal reflux with wireless <span>pH</span> monitoring in <span>French</span> bulldogs with sliding hiatal herniation Open
Background Sliding hiatal herniation (SHH) and gastroesophageal reflux (GER) commonly occur in French bulldogs. Wireless pH monitoring can quantitatively assess acidic GER in dogs affected by SHH. Hypothesis/Objectives Measure acidic GER i…
View article: Letter regarding “Fuzapladib in a randomized controlled multicenter masked study in dogs with presumptive acute onset pancreatitis”
Letter regarding “Fuzapladib in a randomized controlled multicenter masked study in dogs with presumptive acute onset pancreatitis” Open
We read with interest the article by Steiner et al,1 that claims that administration of fuzapladib is safe and effective in reducing 2 clinical scores in dogs with acute pancreatitis (AP). We commend Steiner et al for their efforts in addr…
View article: Characterization of the microbiome and volatile compounds in anal gland secretions from domestic cats (Felis catus) using metagenomics and metabolomics
Characterization of the microbiome and volatile compounds in anal gland secretions from domestic cats (Felis catus) using metagenomics and metabolomics Open
Many mammals rely on volatile organic chemical compounds (VOCs) produced by bacteria for their communication and behavior, though little is known about the exact molecular mechanisms or bacterial species that are responsible. We used metag…
View article: Evaluation of gastroprotectant administration in hospitalized cats in a tertiary referral hospital
Evaluation of gastroprotectant administration in hospitalized cats in a tertiary referral hospital Open
Objectives The primary objective of this study was to evaluate the prescription patterns and appropriateness of the use of gastroprotectant medication in cats. Methods Pharmacy dispensation logs from an academic tertiary referral center we…
View article: Characterization of the microbiome and volatile compounds in anal gland secretions from domestic cats (Felis catus) using metagenomics and metabolomics
Characterization of the microbiome and volatile compounds in anal gland secretions from domestic cats (Felis catus) using metagenomics and metabolomics Open
Animals rely on volatile chemical compounds for their communication and behavior. Many of these compounds are sequestered in endocrine and exocrine glands and are synthesized by anaerobic microbes. While the volatile organic compound (VOC)…
View article: Association of folate concentrations with clinical signs and laboratory markers of chronic enteropathy in dogs
Association of folate concentrations with clinical signs and laboratory markers of chronic enteropathy in dogs Open
Background Serum folate is considered a biomarker of chronic enteropathy (CE) in dogs, but few studies have examined associations with markers of CE. Hypothesis/Objectives To evaluate serum folate concentrations in dogs with and without CE…
View article: Tyzzer disease in 19 preweaned orphaned kittens
Tyzzer disease in 19 preweaned orphaned kittens Open
Clostridium piliforme, the agent of Tyzzer disease, has traditionally not been considered a major pathogen of cats. We queried the database of the Pathology Service of the Veterinary Medical Teaching Hospital, University of California–Davi…
View article: Characterization of clinicopathologic and abdominal ultrasound findings in dogs with glucocorticoid deficient hypoadrenocorticism
Characterization of clinicopathologic and abdominal ultrasound findings in dogs with glucocorticoid deficient hypoadrenocorticism Open
Background Clinical findings of glucocorticoid‐deficient hypoadrenocorticism (GDH) can overlap with other diseases, presenting a diagnostic challenge. Objectives Describe clinicopathologic and ultrasonographic features of dogs with GDH and…
View article: A Comparative Assessment of the Diagnosis of Swallowing Impairment and Gastroesophageal Reflux in Canines and Humans
A Comparative Assessment of the Diagnosis of Swallowing Impairment and Gastroesophageal Reflux in Canines and Humans Open
Swallowing impairment is a highly prevalent and clinically significant problem affecting people and dogs. There are myriad causes of swallowing impairment of which gastroesophageal reflux is the most common in both species. Similarities in…
View article: A comparative analysis of two unrelated outbreaks in Latvia and Australia of acquired idiopathic megaesophagus in dogs fed two brands of commercial dry dog foods: 398 cases (2014–2018)
A comparative analysis of two unrelated outbreaks in Latvia and Australia of acquired idiopathic megaesophagus in dogs fed two brands of commercial dry dog foods: 398 cases (2014–2018) Open
CASE DESCRIPTION In Latvia in 2014, acquired idiopathic megaesophagus (AIME) was observed in increased numbers of dogs that consumed varieties of 1 brand of dog food. Within 2 years, 253 dogs were affected. In Australia in November 2017, 6…
View article: Efficacy of a micronized, nanocrystal fenofibrate formulation in treatment of hyperlipidemia in dogs
Efficacy of a micronized, nanocrystal fenofibrate formulation in treatment of hyperlipidemia in dogs Open
Background Safe, effective, and readily available drug therapies are required for the management of hyperlipidemia and its associated complications in dogs. Objectives To investigate the efficacy of a micronized, nanocrystal formulation of…
View article: Sarcoglycan A mutation in miniature dachshund dogs causes limb-girdle muscular dystrophy 2D
Sarcoglycan A mutation in miniature dachshund dogs causes limb-girdle muscular dystrophy 2D Open
Background A cohort of related miniature dachshund dogs with exercise intolerance, stiff gait, dysphagia, myoglobinuria, and markedly elevated serum creatine kinase activities were identified. Methods Muscle biopsy histopathology, immunofl…
View article: Sarcoglycan A Mutation in Miniature Dachshund Dogs Causes Limb Girdle Muscular Dystrophy 2D
Sarcoglycan A Mutation in Miniature Dachshund Dogs Causes Limb Girdle Muscular Dystrophy 2D Open
BackgroundA cohort of related miniature dachshund dogs with exercise intolerance, stiff gait, dysphagia, myoglobinuria and markedly elevated serum creatine kinase activities were identified. MethodsMuscle biopsy histopathology, immunofluor…
View article: Clinical findings, diagnostic test results, and treatment outcome in cats with hiatal hernia: 31 cases (1995‐2018)
Clinical findings, diagnostic test results, and treatment outcome in cats with hiatal hernia: 31 cases (1995‐2018) Open
Background Information regarding clinical signs, assessment, treatment, and outcome in cats with hiatal hernia (HH) is limited. Objectives To characterize the clinical presentation of HH and medical and surgical outcomes in a cohort of aff…
View article: Use of video capsule endoscopy to identify gastrointestinal lesions in dogs with microcytosis or gastrointestinal hemorrhage
Use of video capsule endoscopy to identify gastrointestinal lesions in dogs with microcytosis or gastrointestinal hemorrhage Open
Background Video capsule endoscopy (VCE) is a noninvasive imaging modality that can identify mucosal lesions not detected with traditional endoscopy or abdominal sonography. In people, VCE is used in diagnostic and management protocols of …
View article: Successful management of 3 dogs with colonic pythiosis using itraconzaole, terbinafine, and prednisone
Successful management of 3 dogs with colonic pythiosis using itraconzaole, terbinafine, and prednisone Open
Gastrointestinal (GI) pythiosis is a severe and often fatal disease in dogs that traditionally has been poorly responsive to medical treatment. Although aggressive surgical resection with wide margins is the most consistently effective tre…
View article: Prevalence of Salmonella in juvenile dogs affected with parvoviral enteritis
Prevalence of Salmonella in juvenile dogs affected with parvoviral enteritis Open
Salmonellosis is a disease of major zoonotic importance and canine parvovirus is a potentially fatal cause of canine enteritis with a world-wide distribution. Persistent isolation of Salmonella during routine environmental sampling surveys…
View article: ACVIM consensus statement: Support for rational administration of gastrointestinal protectants to dogs and cats
ACVIM consensus statement: Support for rational administration of gastrointestinal protectants to dogs and cats Open
The gastrointestinal (GI) mucosal barrier is continuously exposed to noxious toxins, reactive oxygen species, microbes, and drugs, leading to the development of inflammatory, erosive, and ultimately ulcerative lesions. This report offers a…
View article: Effects of preservation method on canine ( <i>Canis lupus familiaris</i> ) fecal microbiota
Effects of preservation method on canine ( <i>Canis lupus familiaris</i> ) fecal microbiota Open
Studies involving gut microbiome analysis play an increasing role in the evaluation of health and disease in humans and animals alike. Fecal sampling methods for DNA preservation in laboratory, clinical, and field settings can greatly infl…
View article: Effects of preservation method on canine ( <i>Canis lupus familiaris</i> ) fecal microbiota
Effects of preservation method on canine ( <i>Canis lupus familiaris</i> ) fecal microbiota Open
Studies involving gut microbiome analysis play an increasing role in the evaluation of health and disease in humans and animals alike. Fecal sampling methods for DNA preservation in laboratory, clinical, and field settings can greatly infl…
View article: Effects of preservation method on canine (<i>Canis lupus familiaris</i>) fecal microbiota
Effects of preservation method on canine (<i>Canis lupus familiaris</i>) fecal microbiota Open
Studies involving gut microbiome analysis play an increasing role in the evaluation of health and disease in humans and animals alike. Fecal sampling methods for DNA preservation in laboratory, clinical, and field settings can greatly infl…
View article: Effect of Laparoscopic‐assisted Gastropexy on Gastrointestinal Transit Time in Dogs
Effect of Laparoscopic‐assisted Gastropexy on Gastrointestinal Transit Time in Dogs Open
Background Prophylactic gastropexy has been promoted as a means of preventing gastric volvulus during gastric dilatation and volvulus ( GDV ) syndrome. Little is known about the impact of gastropexy on gastrointestinal transit time. Hypoth…
View article: Evaluation of Two Dry Commercial Therapeutic Diets for the Management of Feline Chronic Gastroenteropathy
Evaluation of Two Dry Commercial Therapeutic Diets for the Management of Feline Chronic Gastroenteropathy Open
Management of feline chronic gastroenteropathies has included intervention with both veterinary therapeutic formulas designed to manage non-specific gastrointestinal disorders and those designed with limited novel or hydrolyzed ingredients…