Shengjun Ta
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Comparison of serum-ascites albumin gradient and platelet count/splenic diameter ratio in predicting esophageal varices in cirrhosis of liver Open
Background: Prediction of esophageal varices (EV) in cirrhotic patients by non-invasive methods is of greatest importance as it may decrease medical and economic load related to screening. In this study, we aim to validate and compare the …
View article: Evaluating the Effectiveness of Parameter-Efficient Fine-Tuning in Genomic Classification Tasks
Evaluating the Effectiveness of Parameter-Efficient Fine-Tuning in Genomic Classification Tasks Open
Foundation models are increasingly being leveraged for biological tasks. To address the high memory requirements of fine-tuning large pre-trained language models, parameter efficient fine-tuning (PEFT) methods are also being increasingly u…
A Prospective Study on Clinical Profile, Anti Microbial Susceptibility and Treatment Outcome of Less Common Non Lactose Fermenting Gram Negative Bacilli in ICU Open
INTRODUCTION: Non-lactose fermenting Gram-negative bacilli (NLFGNB) account for approximately 15% of Gram-negative bacteria isolated from clinical specimens. While these organisms are typically of low virulence, they exhibit significant an…
Altered Lactylation Myocardial Tissue May Contribute to a More Severe Energy-Deprived State of the Tissue and Left Ventricular Outflow Tract Obstruction in HOCM Open
Hypertrophic cardiomyopathy (HCM) is the most common hereditary cardiovascular disease. In general, obstructive hypertrophic cardiomyopathy (HOCM) is more closely related to severe clinical symptoms and adverse clinical outcomes. Therefore…
View article: Impact of Combining Ultrasound Parameter and the Caprini Score on Predicting Lower Extremity Deep Venous Thrombosis After Orthopedic Surgery
Impact of Combining Ultrasound Parameter and the Caprini Score on Predicting Lower Extremity Deep Venous Thrombosis After Orthopedic Surgery Open
AIMS: This study combined a new ultrasound venous filling degree (VFD) parameter with the Caprini score to assess the clinical value of the Caprini score in predicting deep venous thrombosis (DVT) of the lower extremities. METHODS: This re…
View article: Percutaneous intramyocardial septal radiofrequency ablation: a novel treatment for drug-refractory non-obstructive hypertrophic cardiomyopathy with severe septal hypertrophy
Percutaneous intramyocardial septal radiofrequency ablation: a novel treatment for drug-refractory non-obstructive hypertrophic cardiomyopathy with severe septal hypertrophy Open
Background Patients with drug-refractory non-obstructive hypertrophic cardiomyopathy (NOHCM) lack effective invasive treatment options. This study aimed to evaluate the safety and effectiveness of percutaneous intramyocardial septal radiof…
A unique presentation of systolic anterior motion of the mitral valve in a patient with obstructive hypertrophic cardiomyopathy and recurrent syncope: a case report Open
Background Systolic anterior motion (SAM) of the mitral valve is a hallmark feature of hypertrophic obstructive cardiomyopathy (HOCM) and a primary cause of dynamic left ventricular outflow tract obstruction. This case report highlights an…
Segmenting Based on UNETR Network and 3D Reconstruction of Interventricular Septal‐Free Wall Structure Open
Background: Percutaneous intramuscular septal radiofrequency ablation (PIMSRA) provi des an innovative alternative to septal myectomy (SM) and alcohol septal ablation (ASA). The precise segmentation of the interventricular septal is of par…
Echocardiography-Guided Radiofrequency Ablation for Cardiac Tumors Open
TARFACT is a novel palliative treatment option for cardiac tumors, reducing accessible tumors and improving clinical symptoms in a preliminary group of patients. (Cardiac Tumors Interventional [Radio Frequency/Laser Ablation] Therapy [CTIH…
View article: Echocardiography-guided percutaneous intramyocardial alginate hydrogel implants for heart failure: canine models with 6-month outcomes
Echocardiography-guided percutaneous intramyocardial alginate hydrogel implants for heart failure: canine models with 6-month outcomes Open
Background Echocardiography-guided percutaneous intramyocardial alginate-hydrogel implantation (PIMAHI) is a novel treatment approach for heart failure (HF). We validated PIMAHI safety and efficacy in canine HF models. Methods Fourteen can…
Pompe disease in China: clinical and molecular characteristics Open
Background Pompe disease (PD) is a rare, progressive, and autosomal recessive lysosomal storage disorder caused by mutations in the acid α -glucosidase gene. The clinical course and molecular mechanism of this disease in China have not bee…
View article: Percutaneous Intramyocardial Septal Cryoablation for Hypertrophic Cardiomyopathy: A Canine Model with 6 months Follow-up
Percutaneous Intramyocardial Septal Cryoablation for Hypertrophic Cardiomyopathy: A Canine Model with 6 months Follow-up Open
BACKGROUND Echocardiography-guided percutaneous intramyocardial septal radiofrequency ablation (PIMSRA, Liwen procedure) is a novel treatment option for hypertrophic obstructive cardiomyopathy (HOCM). The safety and feasibility of using th…
Association between Severity of Diabetic Retinopathy and Cardiac Function in Patients with Type 2 Diabetes Open
Background. The purpose of this research was to assess the relationship between the severity of diabetic retinopathy (DR) and indexes of left ventricle (LV) structure and function in type 2 diabetes mellitus (T2DM). Methods. Retrospective …
Assessment of subclinical left ventricular systolic dysfunction in patients with type 2 diabetes: Relationship with <span>HbA1c</span> and microvascular complications Open
Background We aimed to examine the association between glycated hemoglobin (HbA1c), microvascular complications, and subclinical left ventricular (LV) systolic dysfunction, and to determine the strength of the correlation in asymptomatic p…
Association between triglyceride glucose index and subclinical left ventricular systolic dysfunction in patients with type 2 diabetes Open
Background Triglyceride glucose (TyG) index has been considered a new biomarker for diagnosis of angiocardiopathy and insulin resistance. However, the association of TyG index with subclinical left ventricular (LV) systolic dysfunction sti…
First-in-man application of Liwen RF™ ablation system in the treatment of drug-resistant hypertrophic obstructive cardiomyopathy Open
Objectives This study sought to evaluate the clinical applicability of the Liwen Liu RF™ ablation system for percutaneous intramyocardial septal radiofrequency ablation (PIMSRA). Background Data on new cardiac radiofrequency ablation devic…
Percutaneous Intramyocardial Septal Radiofrequency Ablation in Patients With Drug-Refractory Hypertrophic Obstructive Cardiomyopathy Open
This study found that PIMSRA in patients with drug-refractory HOCM may be an effective procedure for relief of left ventricular outflow tract obstruction and symptoms with acceptable complication rates. These results are encouraging and su…
Trans-Septal Myocardial Biopsy in Hypertrophic Cardiomyopathy Using the Liwen Procedure: An Introduction of a Novel Technique Open
Objective. The purpose of this study was to evaluate the feasibility and safety of myocardial biopsy using a new approach, the Liwen procedure. Background. Myocardial biopsy is essential when other methods could not differentiate other eti…
Predictors of cardiac involvement and survival in patients with primary systemic light-chain amyloidosis: roles of the clinical, chemical, and 3-D speckle tracking echocardiography parameters Open
Background Light-chain (AL) amyloidosis is the most common type of systemic amyloidosis with poor prognosis. Currently, the predictors of cardiac involvement and prognostic staging systems are primarily based on conventional echocardiograp…
[Corrigendum] A germline alteration of ERBB2 increases the risk of breast cancer in Chinese Han women with a familial history of malignant tumors Open
[This corrects the article DOI: 10.3892/ol.2019.10646.].
A germline alteration of ERBB2 increases the risk of breast cancer in Chinese Han women with a familial history of malignant tumors Open
Previous studies have demonstrated that a family history of breast cancer is considered a risk factor, and hereditary factors may be involved in breast cancer pathogenesis. Next-generation sequencing techniques were used to analyze 111 can…