Starley B. Shade
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View article: Socioeconomic and demographic determinants of tobacco use in Kenya: A secondary data analysis of findings from the Kenya Demographic and Health Survey 2022
Socioeconomic and demographic determinants of tobacco use in Kenya: A secondary data analysis of findings from the Kenya Demographic and Health Survey 2022 Open
The observed declines in tobacco use, especially among males, suggest that current tobacco control efforts are positively impacting public health. Given the financial strain of health costs, preventive interventions are crucial. Research o…
View article: Dynamic choice HIV prevention with long-acting injectable cabotegravir pre-exposure prophylaxis in east, central, southern, and west Africa: a cost-effectiveness modelling analysis
Dynamic choice HIV prevention with long-acting injectable cabotegravir pre-exposure prophylaxis in east, central, southern, and west Africa: a cost-effectiveness modelling analysis Open
US National Institutes of Health.
View article: Influence of alcohol-serving venue characteristics on yield of HIV status-neutral screening in rural East Africa
Influence of alcohol-serving venue characteristics on yield of HIV status-neutral screening in rural East Africa Open
Alcohol-serving venues are high-risk sites for HIV transmission in East Africa. Understanding how venue characteristics influence HIV screening outcomes may help to target venue-based outreach. In eight rural communities in Kenya and Ugand…
View article: Innovative administration of long-acting injectables for HIV treatment enhancement at home (INVITE-HOME): implementation science study protocol
Innovative administration of long-acting injectables for HIV treatment enhancement at home (INVITE-HOME): implementation science study protocol Open
Introduction There is high interest in long-acting injectable antiretroviral therapy (LAI-ART) among people with HIV (PWH), with many conveniences for uptake and persistence. However, both patients and clinicians have expressed important b…
View article: Receipt of prescribed opioids is associated with achieving quality healthcare indicators among patients with chronic non-cancer pain
Receipt of prescribed opioids is associated with achieving quality healthcare indicators among patients with chronic non-cancer pain Open
Background In response to increasing opioid overdose, US providers reduced opioid prescribing, resulting in several unintended consequences. Methods We assessed the impact of opioid receipt on quality health indicators (QHI) among 300 adul…
View article: Practical application of hybrid effectiveness–implementation studies for intervention research
Practical application of hybrid effectiveness–implementation studies for intervention research Open
Hybrid effectiveness–implementation studies have emerged to address design challenges that researchers face when assessing evidence-based intervention implementation in real-world settings. Hybrid studies maximize the usefulness of effecti…
View article: Delivering guideline-directed medical therapy for heart failure with reduced ejection fraction as an over-encapsulated polypill: rationale and protocol for the COMBO-HF-X pilot crossover randomised clinical trial
Delivering guideline-directed medical therapy for heart failure with reduced ejection fraction as an over-encapsulated polypill: rationale and protocol for the COMBO-HF-X pilot crossover randomised clinical trial Open
Introduction A four-drug regimen of guideline-directed medical therapy (GDMT) for heart failure with reduced ejection fraction (HFrEF) is underused, in part due to prescriber inertia and low patient adherence. Although fixed-dose combinati…
View article: Cost Effectiveness Analyses for Sequential Multiple Assignment Randomized Trials
Cost Effectiveness Analyses for Sequential Multiple Assignment Randomized Trials Open
Sequential multiple assignment randomized trials (SMARTs) have grown in popularity in recent years, and many of their study protocols propose conducting a cost effectiveness analysis of the adaptive strategies embedded within them. The cos…
View article: Measuring Implementation Outcomes Change Over Time Using an Adapted Checklist for Assessing Readiness to Implement (CARI)
Measuring Implementation Outcomes Change Over Time Using an Adapted Checklist for Assessing Readiness to Implement (CARI) Open
In 2017, the Health Resources and Services Administration’s HIV/AIDS Bureau funded an Evaluation Center (EC) to assess the rapid implementation of 11 evidence-informed interventions at 25 HIV care and treatment providers across the U.S. Th…
View article: Cost-effectiveness of leveraging existing HIV primary health systems and community health workers for hypertension screening and treatment in Africa: An individual-based modeling study
Cost-effectiveness of leveraging existing HIV primary health systems and community health workers for hypertension screening and treatment in Africa: An individual-based modeling study Open
Background Cardiovascular disease (CVD) morbidity and mortality is increasing in Africa, largely due to undiagnosed and untreated hypertension. Approaches that leverage existing primary health systems could improve hypertension treatment a…
View article: Cost-effectiveness of leveraging existing HIV primary health systems and community health workers for hypertension screening and treatment in Africa: an individual-based modelling study
Cost-effectiveness of leveraging existing HIV primary health systems and community health workers for hypertension screening and treatment in Africa: an individual-based modelling study Open
Background Cardiovascular disease (CVD) morbidity and mortality is increasing in Africa, largely due to undiagnosed and untreated hypertension. Approaches that leverage existing primary health systems could improve hypertension treatment a…
View article: Understanding HIV care providers’ support for tobacco cessation among people living with HIV in Western Kenya: a formative qualitative study
Understanding HIV care providers’ support for tobacco cessation among people living with HIV in Western Kenya: a formative qualitative study Open
Introduction Healthcare providers are required to support people living with HIV (PLHIV) to quit tobacco use for improved health outcomes, but it is unclear to what extent they adhere to these requirements. We examined HIV care providers a…
View article: User-informed tailoring of electronic and in-person peer navigation strategies to improve retention in HIV care for adolescents and young adults: a qualitative inquiry
User-informed tailoring of electronic and in-person peer navigation strategies to improve retention in HIV care for adolescents and young adults: a qualitative inquiry Open
Poor adherence and retention in HIV care remain a major challenge among adolescents and young adults (AYA) living with HIV in sub-Saharan Africa (SSA). Strategies are urgently required to support AYA to remain in care for better health out…
View article: The effect of an intervention to promote isoniazid preventive therapy on leadership and management abilities
The effect of an intervention to promote isoniazid preventive therapy on leadership and management abilities Open
BACKGROUNDAcross sub-Saharan Africa, mid-level healthcare managers oversee implementation of national guidelines. It remains unclear whether leadership and management training can improve population health outcomes.METHODSWe sought to eval…
View article: Mid-level managers’ perspectives on implementing isoniazid preventive therapy for people living with HIV in Ugandan health districts: a qualitative study
Mid-level managers’ perspectives on implementing isoniazid preventive therapy for people living with HIV in Ugandan health districts: a qualitative study Open
View article: A Multi-Component Integrated HIV and Hypertension Care Model Improves Hypertension Screening and Control in Rural Uganda: A Cluster Randomized Trial
A Multi-Component Integrated HIV and Hypertension Care Model Improves Hypertension Screening and Control in Rural Uganda: A Cluster Randomized Trial Open
View article: Lessons learned from implementing a diversity, equity, and inclusion curriculum for health research professionals at a large academic research institution
Lessons learned from implementing a diversity, equity, and inclusion curriculum for health research professionals at a large academic research institution Open
Objective: Despite advances in incorporating diversity and structural competency into medical education curriculum, there is limited curriculum for public health research professionals. We developed and implemented a four-part diversity, e…
View article: Stimulant use and opioid-related harm in patients on long-term opioids for chronic pain
Stimulant use and opioid-related harm in patients on long-term opioids for chronic pain Open
Despite no association between a stimulant-positive UDT and subsequent opioid-related harm, there was an association with subsequent LTOT discontinuation, with heterogeneity across clinical groups. Detection of stimulant use should result …
View article: Impact of San Francisco’s New Street crisis response Team on Service use among people experiencing homelessness with mental and substance use disorders: A mixed methods study protocol
Impact of San Francisco’s New Street crisis response Team on Service use among people experiencing homelessness with mental and substance use disorders: A mixed methods study protocol Open
Mobile crisis services for people experiencing distress related to mental health or substance use are expanding rapidly across the US, yet there is little evidence to support these specific models of care. These new programs present a uniq…
View article: OA-317 A multi-component integrated HIV/HTN care model improves hypertension screening and control in rural Uganda: a cluster randomized trial
OA-317 A multi-component integrated HIV/HTN care model improves hypertension screening and control in rural Uganda: a cluster randomized trial Open
Background The prevalence of hypertension (HTN) is increasing among people with HIV (PHIV) across sub-Saharan Africa. However, little data exist on the effectiveness of integrated HIV and HTN care delivery systems on blood pressure [BP] sc…
View article: A guaranteed income intervention to improve the health and financial well-being of low-income black emerging adults: study protocol for the Black Economic Equity Movement randomized controlled crossover trial
A guaranteed income intervention to improve the health and financial well-being of low-income black emerging adults: study protocol for the Black Economic Equity Movement randomized controlled crossover trial Open
Background Economic inequity systematically affects Black emerging adults (BEA), aged 18–24, and their healthy trajectory into adulthood. Guaranteed income (GI)–temporary, unconditional cash payments–is gaining traction as a policy solutio…
View article: Dynamic choice HIV prevention intervention at outpatient departments in rural Kenya and Uganda
Dynamic choice HIV prevention intervention at outpatient departments in rural Kenya and Uganda Open
Objective: HIV prevention service delivery models that offer product choices, and the option to change preferences over time, may increase prevention coverage. Outpatient departments in sub-Saharan Africa diagnose a high proportion of new …
View article: Implementation of Kenya Electronic Medical Records (KenyaEMR): Costs and Efficiencies
Implementation of Kenya Electronic Medical Records (KenyaEMR): Costs and Efficiencies Open
Background: Electronic medical record (EMR) rollout is a key element of health systems strengthening activities.To facilitate national rollout and country ownership of KenyaEMR, we assessed costs associated with development and pointof-car…
View article: A multilevel health system intervention for virological suppression in adolescents and young adults living with HIV in rural Kenya and Uganda (SEARCH-Youth): a cluster randomised trial
A multilevel health system intervention for virological suppression in adolescents and young adults living with HIV in rural Kenya and Uganda (SEARCH-Youth): a cluster randomised trial Open
Eunice Kennedy Shriver National Institute of Child Health and Human Development, US National Institutes of Health.
View article: Examining the Impact of State-Level Factors on HIV Testing for Medicaid Enrollees With Schizophrenia
Examining the Impact of State-Level Factors on HIV Testing for Medicaid Enrollees With Schizophrenia Open
Background: People with schizophrenia experience unique barriers to routine HIV testing, despite increased risk of HIV compared with the general US population. Little is known about how health care delivery system factors affect testing ra…
View article: Rapid start antiretroviral therapies for improved engagement in HIV care: implementation science evaluation protocol
Rapid start antiretroviral therapies for improved engagement in HIV care: implementation science evaluation protocol Open
Background In 2020, the Health Resources and Services Administration’s HIV/AIDS Bureau funded an initiative to promote implementation of rapid antiretroviral therapy initiation in 14 HIV treatment settings across the U.S. The goal of this …
View article: Long-Acting Injectable Cabotegravir for HIV Preexposure Prophylaxis Among Sexual and Gender Minorities: Protocol for an Implementation Study
Long-Acting Injectable Cabotegravir for HIV Preexposure Prophylaxis Among Sexual and Gender Minorities: Protocol for an Implementation Study Open
Background Long-acting injectable cabotegravir (CAB-LA) for preexposure prophylaxis (PrEP) has proven efficacious in randomized controlled trials. Further research is critical to evaluate its effectiveness in real-world settings and identi…
View article: Cost comparison of a rapid results initiative against standard clinic-based model to scale-up voluntary medical male circumcision in Kenya
Cost comparison of a rapid results initiative against standard clinic-based model to scale-up voluntary medical male circumcision in Kenya Open
Voluntary male medical circumcision (VMMC) reduces HIV acquisition by up to 60%. Kenya has successfully scaled up VMMC to an estimated 91% of eligible men and boys in certain regions in combination due to VMMC and cultural circumcisions. V…
View article: Adaptive Strategies for Retention in Care among Persons Living with HIV
Adaptive Strategies for Retention in Care among Persons Living with HIV Open
Active interventions to prevent retention lapses followed by navigation for those who lapse and maintenance of initial intervention for those without lapse resulted in best overall retention and viral suppression among the strategies studi…
View article: Costs of a Brief Alcohol Consumption Reduction Intervention for Persons Living with HIV in Southwestern Uganda: Comparisons of Live Versus Automated Cell Phone-Based Booster Components
Costs of a Brief Alcohol Consumption Reduction Intervention for Persons Living with HIV in Southwestern Uganda: Comparisons of Live Versus Automated Cell Phone-Based Booster Components Open
Low-cost interventions are needed to reduce alcohol use among persons with HIV (PWH) in low-income settings. Brief alcohol interventions hold promise, and technology may efficiently deliver brief intervention components with high frequency…