Stefan Antonowicz
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View article: Deep Learning Based Segmentation of Blood Vessels from H&E Stained Oesophageal Adenocarcinoma Whole-Slide Images
Deep Learning Based Segmentation of Blood Vessels from H&E Stained Oesophageal Adenocarcinoma Whole-Slide Images Open
Blood vessels (BVs) play a critical role in the Tumor Micro-Environment (TME), potentially influencing cancer progression and treatment response. However, manually quantifying BVs in Hematoxylin and Eosin (H&E) stained images is challengin…
View article: Medical management of painful achalasia: a patient-driven systematic review
Medical management of painful achalasia: a patient-driven systematic review Open
Summary Achalasia is a rare esophageal disorder characterized by abnormal esophageal motility and swallowing difficulties. Pain and/or spasms often persist or recur despite effective relief of the obstruction. A survey by UK charity ‘Achal…
View article: Supplementary Figure from Progress with Metabolomic Blood Tests for Gastrointestinal Cancer Diagnosis—An Assessment of Biomarker Translation
Supplementary Figure from Progress with Metabolomic Blood Tests for Gastrointestinal Cancer Diagnosis—An Assessment of Biomarker Translation Open
Supplementary Figure from Progress with Metabolomic Blood Tests for Gastrointestinal Cancer Diagnosis—An Assessment of Biomarker Translation
View article: Data from Progress with Metabolomic Blood Tests for Gastrointestinal Cancer Diagnosis—An Assessment of Biomarker Translation
Data from Progress with Metabolomic Blood Tests for Gastrointestinal Cancer Diagnosis—An Assessment of Biomarker Translation Open
There is an urgent need for cost-effective, non-invasive tools to detect early stages of gastrointestinal cancer (colorectal, gastric, and esophageal cancers). Despite many publications suggesting circulating metabolites acting as accurate…
View article: Supplementary Figure from Progress with Metabolomic Blood Tests for Gastrointestinal Cancer Diagnosis—An Assessment of Biomarker Translation
Supplementary Figure from Progress with Metabolomic Blood Tests for Gastrointestinal Cancer Diagnosis—An Assessment of Biomarker Translation Open
Supplementary Figure from Progress with Metabolomic Blood Tests for Gastrointestinal Cancer Diagnosis—An Assessment of Biomarker Translation
View article: Data from Progress with Metabolomic Blood Tests for Gastrointestinal Cancer Diagnosis—An Assessment of Biomarker Translation
Data from Progress with Metabolomic Blood Tests for Gastrointestinal Cancer Diagnosis—An Assessment of Biomarker Translation Open
There is an urgent need for cost-effective, non-invasive tools to detect early stages of gastrointestinal cancer (colorectal, gastric, and esophageal cancers). Despite many publications suggesting circulating metabolites acting as accurate…
View article: Supplementary Figures 1 and 2 from Tyrosine, Phenylalanine, and Tryptophan in Gastroesophageal Malignancy: A Systematic Review
Supplementary Figures 1 and 2 from Tyrosine, Phenylalanine, and Tryptophan in Gastroesophageal Malignancy: A Systematic Review Open
Supplementary Figures 1 and 2: QUADAS-2 Assessments of study quality. Supplementary figure 1 - Assessment of risk of bias Supplementary figure 2 - Assessment of applicability concerns
View article: Supplementary Figure Legends from Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry
Supplementary Figure Legends from Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry Open
Supplementary Figure Legends
View article: Data from <i>De Novo</i> Lipogenesis Alters the Phospholipidome of Esophageal Adenocarcinoma
Data from <i>De Novo</i> Lipogenesis Alters the Phospholipidome of Esophageal Adenocarcinoma Open
The incidence of esophageal adenocarcinoma is rising, survival remains poor, and new tools to improve early diagnosis and precise treatment are needed. Cancer phospholipidomes quantified with mass spectrometry imaging (MSI) can support obj…
View article: Data from <i>De Novo</i> Lipogenesis Alters the Phospholipidome of Esophageal Adenocarcinoma
Data from <i>De Novo</i> Lipogenesis Alters the Phospholipidome of Esophageal Adenocarcinoma Open
The incidence of esophageal adenocarcinoma is rising, survival remains poor, and new tools to improve early diagnosis and precise treatment are needed. Cancer phospholipidomes quantified with mass spectrometry imaging (MSI) can support obj…
View article: Supplementary Figures 1 and 2 from Tyrosine, Phenylalanine, and Tryptophan in Gastroesophageal Malignancy: A Systematic Review
Supplementary Figures 1 and 2 from Tyrosine, Phenylalanine, and Tryptophan in Gastroesophageal Malignancy: A Systematic Review Open
Supplementary Figures 1 and 2: QUADAS-2 Assessments of study quality. Supplementary figure 1 - Assessment of risk of bias Supplementary figure 2 - Assessment of applicability concerns
View article: Supplementary Figures and Tables from Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry
Supplementary Figures and Tables from Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry Open
Table S1: Glycerophospholipid relative abundances compared between lymph node metastases (LNM) and primary tumor by means of ANOVA. Table S2: Glycerophospholipid relative abundances compared between malignant tissue (lymph node metastases …
View article: Supplementary Tables S1-S4 from Diagnostic Metabolomic Blood Tests for Endoluminal Gastrointestinal Cancer—A Systematic Review and Assessment of Quality
Supplementary Tables S1-S4 from Diagnostic Metabolomic Blood Tests for Endoluminal Gastrointestinal Cancer—A Systematic Review and Assessment of Quality Open
Supplementary Table S1: QUADAS-2 assessment. Supplementary Table S2: Index test methodological quality Supplementary Table S3: STARD checklist assessment Supplementary Table S4: All significant metabolites
View article: Supplementary Figure S1 from Diagnostic Metabolomic Blood Tests for Endoluminal Gastrointestinal Cancer—A Systematic Review and Assessment of Quality
Supplementary Figure S1 from Diagnostic Metabolomic Blood Tests for Endoluminal Gastrointestinal Cancer—A Systematic Review and Assessment of Quality Open
Supplementary Figure S1: Summary of QUADAS-2 methodological quality assessment
View article: Data from Diagnostic Metabolomic Blood Tests for Endoluminal Gastrointestinal Cancer—A Systematic Review and Assessment of Quality
Data from Diagnostic Metabolomic Blood Tests for Endoluminal Gastrointestinal Cancer—A Systematic Review and Assessment of Quality Open
Advances in analytics have resulted in metabolomic blood tests being developed for the detection of cancer. This systematic review aims to assess the diagnostic accuracy of blood-based metabolomic biomarkers for endoluminal gastrointestina…
View article: Supplementary Material and Methods from Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry
Supplementary Material and Methods from Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry Open
Full methodological details of data analysis with respect to: tissue specific mass spectra extraction; data pre-processing (mass range selection, peak alignment, normalization, de-noising, data averaging); multivariate statistical models; …
View article: Data from Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry
Data from Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry Open
Histopathological assessment of lymph node metastases (LNM) depends on subjective analysis of cellular morphology with inter-/intraobserver variability. In this study, LNM from esophageal adenocarcinoma was objectively detected using desor…
View article: Supplementary Figures and Tables from Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry
Supplementary Figures and Tables from Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry Open
Table S1: Glycerophospholipid relative abundances compared between lymph node metastases (LNM) and primary tumor by means of ANOVA. Table S2: Glycerophospholipid relative abundances compared between malignant tissue (lymph node metastases …
View article: Supplementary Data from <i>De Novo</i> Lipogenesis Alters the Phospholipidome of Esophageal Adenocarcinoma
Supplementary Data from <i>De Novo</i> Lipogenesis Alters the Phospholipidome of Esophageal Adenocarcinoma Open
The Supplementary information file contains: (i) Supplementary Methods, concerning PCR primers, antibodies and explanation of the chemometric approach. (ii) Supplementary Figures 1-4, which provide extended data for the multivariable model…
View article: Supplementary Tables S1-S4 from Diagnostic Metabolomic Blood Tests for Endoluminal Gastrointestinal Cancer—A Systematic Review and Assessment of Quality
Supplementary Tables S1-S4 from Diagnostic Metabolomic Blood Tests for Endoluminal Gastrointestinal Cancer—A Systematic Review and Assessment of Quality Open
Supplementary Table S1: QUADAS-2 assessment. Supplementary Table S2: Index test methodological quality Supplementary Table S3: STARD checklist assessment Supplementary Table S4: All significant metabolites
View article: Supplementary Data from <i>De Novo</i> Lipogenesis Alters the Phospholipidome of Esophageal Adenocarcinoma
Supplementary Data from <i>De Novo</i> Lipogenesis Alters the Phospholipidome of Esophageal Adenocarcinoma Open
The Supplementary information file contains: (i) Supplementary Methods, concerning PCR primers, antibodies and explanation of the chemometric approach. (ii) Supplementary Figures 1-4, which provide extended data for the multivariable model…
View article: Supplementary Material and Methods from Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry
Supplementary Material and Methods from Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry Open
Full methodological details of data analysis with respect to: tissue specific mass spectra extraction; data pre-processing (mass range selection, peak alignment, normalization, de-noising, data averaging); multivariate statistical models; …
View article: Data from Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry
Data from Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry Open
Histopathological assessment of lymph node metastases (LNM) depends on subjective analysis of cellular morphology with inter-/intraobserver variability. In this study, LNM from esophageal adenocarcinoma was objectively detected using desor…
View article: Supplementary Figure S1 from Diagnostic Metabolomic Blood Tests for Endoluminal Gastrointestinal Cancer—A Systematic Review and Assessment of Quality
Supplementary Figure S1 from Diagnostic Metabolomic Blood Tests for Endoluminal Gastrointestinal Cancer—A Systematic Review and Assessment of Quality Open
Supplementary Figure S1: Summary of QUADAS-2 methodological quality assessment
View article: Data from Tyrosine, Phenylalanine, and Tryptophan in Gastroesophageal Malignancy: A Systematic Review
Data from Tyrosine, Phenylalanine, and Tryptophan in Gastroesophageal Malignancy: A Systematic Review Open
Gastroesophageal cancer has a rapidly increasing incidence worldwide and reliable biomarkers are urgently required to facilitate earlier diagnosis and improve survival. The aromatic amino acids tyrosine, phenylalanine, and tryptophan repre…
View article: Supplementary Figure Legends from Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry
Supplementary Figure Legends from Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry Open
Supplementary Figure Legends
View article: Data from Diagnostic Metabolomic Blood Tests for Endoluminal Gastrointestinal Cancer—A Systematic Review and Assessment of Quality
Data from Diagnostic Metabolomic Blood Tests for Endoluminal Gastrointestinal Cancer—A Systematic Review and Assessment of Quality Open
Advances in analytics have resulted in metabolomic blood tests being developed for the detection of cancer. This systematic review aims to assess the diagnostic accuracy of blood-based metabolomic biomarkers for endoluminal gastrointestina…
View article: Data from Tyrosine, Phenylalanine, and Tryptophan in Gastroesophageal Malignancy: A Systematic Review
Data from Tyrosine, Phenylalanine, and Tryptophan in Gastroesophageal Malignancy: A Systematic Review Open
Gastroesophageal cancer has a rapidly increasing incidence worldwide and reliable biomarkers are urgently required to facilitate earlier diagnosis and improve survival. The aromatic amino acids tyrosine, phenylalanine, and tryptophan repre…
View article: OGC P26 The role of inadequate analgesia in care escalation after oesophagectomy
OGC P26 The role of inadequate analgesia in care escalation after oesophagectomy Open
Background There is a paucity of data describing the incidence and causes of escalation in level of care after oesophagectomy for cancer. This study aimed to address this, including the description of baseline predisposing variables, and c…
View article: Progress with Metabolomic Blood Tests for Gastrointestinal Cancer Diagnosis—An Assessment of Biomarker Translation
Progress with Metabolomic Blood Tests for Gastrointestinal Cancer Diagnosis—An Assessment of Biomarker Translation Open
There is an urgent need for cost-effective, non-invasive tools to detect early stages of gastrointestinal cancer (colorectal, gastric, and esophageal cancers). Despite many publications suggesting circulating metabolites acting as accurate…