Stefan Elde
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View article: Simultaneous heart-kidney transplantation outcomes in Asian populations in the United States: A united network for organ sharing database study
Simultaneous heart-kidney transplantation outcomes in Asian populations in the United States: A united network for organ sharing database study Open
Asian recipients demonstrated comparable long-term survival to NHW recipients after HKTx.
View article: Preservation of bronchial artery circulation on ex-vivo lung perfusion
Preservation of bronchial artery circulation on ex-vivo lung perfusion Open
Lungs receive blood supply from the pulmonary and bronchial arteries. After transplantation, lungs uniquely suffer from ischemia and injury to the airways, in part due to the surgical sacrifice of the bronchial artery circulation during pr…
View article: Corrigendum to Ex vivo lung perfusion of pediatric lungs for adult recipients [JTCVS Techniques, Volume 29, 2025]
Corrigendum to Ex vivo lung perfusion of pediatric lungs for adult recipients [JTCVS Techniques, Volume 29, 2025] Open
[This corrects the article DOI: 10.1016/j.xjtc.2024.10.021.].
View article: Stromal cell-derived factor-encapsulated nanoparticles target ischemic myocardium and attenuate myocardial injury via proangiogenic effects
Stromal cell-derived factor-encapsulated nanoparticles target ischemic myocardium and attenuate myocardial injury via proangiogenic effects Open
Lipid bilayer nanoparticles (NPs) with and without stromal cell-derived factor (SDF) were created to target and treat ischemia/reperfusion (I/R)-injured myocardium. Male Wistar rats were subjected to myocardial I/R insult and, at reperfusi…
View article: Application of a degradable thin film to modulate perfusion to post-autotransplantation airways in rats
Application of a degradable thin film to modulate perfusion to post-autotransplantation airways in rats Open
Application of a nanofiber-based, PDO thin film induced a local tissue response that improved perfusion and histologic injury scoring of the transplanted airway in an autotransplant model of airway devascularization. Immune multiplexing su…
View article: Heart-liver transplantation using the en bloc technique: A single-center experience over two decades
Heart-liver transplantation using the en bloc technique: A single-center experience over two decades Open
CHLT is a definitive therapy reserved for patients with multiorgan dysfunction. At our institution, the en bloc technique is the preferred operative approach, as it minimizes cardiac insult, requires fewer anastomoses, minimizes cold ische…
View article: Structural, angiogenic, and immune responses influencing myocardial regeneration: a glimpse into the crucible
Structural, angiogenic, and immune responses influencing myocardial regeneration: a glimpse into the crucible Open
Complete cardiac regeneration remains an elusive therapeutic goal. Although much attention has been focused on cardiomyocyte proliferation, especially in neonatal mammals, recent investigations have unearthed mechanisms by which non-cardio…
View article: Revised Heart Allocation Policy Improved Waitlist Mortality and Waiting Time With Maintained Outcomes in En-Bloc Heart-Lung Transplant Candidates and Recipients
Revised Heart Allocation Policy Improved Waitlist Mortality and Waiting Time With Maintained Outcomes in En-Bloc Heart-Lung Transplant Candidates and Recipients Open
The revised United Network for Organ Sharing heart allocation policy was implemented in October 2018. Using a national transplant database, this study evaluated the transplant rate, waitlist mortality, waiting time, and other outcomes of e…
View article: Biomechanics and clinical outcomes of various conduit configurations in valve sparing aortic root replacement
Biomechanics and clinical outcomes of various conduit configurations in valve sparing aortic root replacement Open
SG demonstrated hemodynamics and biomechanics most closely recapitulating those from the native root with significantly shorter intraoperative times compared with repair using sinus-containing graft. Future in vivo validation studies as we…
View article: Surgical management of severe mitral annular calcification
Surgical management of severe mitral annular calcification Open
Background Surgical management of severe mitral annular calcification (MAC) presents a challenging problem for even the most experienced surgeons. Preoperative planning is the most effective strategy to mitigate risk in these scenarios. MA…
View article: Outcomes of Heart Transplantation Using a Temperature-controlled Hypothermic Storage System
Outcomes of Heart Transplantation Using a Temperature-controlled Hypothermic Storage System Open
Background. The SherpaPak Cardiac Transport System is a novel technology that provides stable, optimal hypothermic control during organ transport. The objectives of this study were to describe our experience using the SherpaPak system and …
View article: Electrophysiologic Conservation of Epicardial Conduction Dynamics After Myocardial Infarction and Natural Heart Regeneration in Newborn Piglets
Electrophysiologic Conservation of Epicardial Conduction Dynamics After Myocardial Infarction and Natural Heart Regeneration in Newborn Piglets Open
Newborn mammals, including piglets, exhibit natural heart regeneration after myocardial infarction (MI) on postnatal day 1 (P1), but this ability is lost by postnatal day 7 (P7). The electrophysiologic properties of this naturally regenera…
View article: Ex vivo aortic valve replacement before orthotopic heart transplantation
Ex vivo aortic valve replacement before orthotopic heart transplantation Open
Central MessageBackbench ex vivo aortic valve replacement is an effective and easily implemented strategy to increase the utilization of donor hearts that would otherwise be declined because of aortic valve pathology. Backbench ex vivo aor…
View article: The Expanding Armamentarium of Innovative Bioengineered Strategies to Augment Cardiovascular Repair and Regeneration
The Expanding Armamentarium of Innovative Bioengineered Strategies to Augment Cardiovascular Repair and Regeneration Open
Cardiovascular disease remains the leading cause of death worldwide. While clinical trials of cell therapy have demonstrated largely neutral results, recent investigations into the mechanisms of natural myocardial regeneration have demonst…
View article: Navigating the Crossroads of Cell Therapy and Natural Heart Regeneration
Navigating the Crossroads of Cell Therapy and Natural Heart Regeneration Open
Cardiovascular disease remains the leading cause of death worldwide despite significant advances in our understanding of the disease and its treatment. Consequently, the therapeutic potential of cell therapy and induction of natural myocar…
View article: A novel alternative to the Commando procedure: Constructing a neo-aortic root by anchoring to the sewing ring of the replaced mitral valve
A novel alternative to the Commando procedure: Constructing a neo-aortic root by anchoring to the sewing ring of the replaced mitral valve Open
Central MessageHere, we report a novel technique for replacement of the mitral and aortic valves via an aortotomy in a patient with recent Stanford type A aortic dissection and multivalve infective endocarditis.See Commentaries on pages 10…