Stefan Hegemann
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View article: Treating Menière’s disease with rimegepant
Treating Menière’s disease with rimegepant Open
A recent hypothesis states that Menière’s disease is caused by inappropriate expression, i.e. enhanced release of the neurotransmitter calcitonin gene-related peptide. Here, we tested this hypothesis by administering rimegepant, a new calc…
View article: Focused Update on Clinical Testing of Otolith Organs
Focused Update on Clinical Testing of Otolith Organs Open
Sensing gravity through the otolith receptors is crucial for bipedal stability and gait. The overall contribution of the otolith organs to eye movements, postural control, and perceptual functions is the basis for clinical testing of otoli…
View article: Focused Update on Clinical Testing of Otolith Organs
Focused Update on Clinical Testing of Otolith Organs Open
The overall contribution of otolith receptors to eye movements, postural control and perceptual functions is the basis for clinical testing of otolith function. With such wide range of contributions, it is important to recognize that the f…
View article: Assessing long-term, vestibulotoxic side effects after gentamicin therapy in neonatal sepsis or infection using video head impulse test
Assessing long-term, vestibulotoxic side effects after gentamicin therapy in neonatal sepsis or infection using video head impulse test Open
Study background Newborn infection and sepsis remain serious problems. Guideline-compliant therapy includes, among other therapeutics, calculated intravenous antibiosis with gentamicin. One of the known side effects of gentamicin is severe…
View article: The effects of COVID-19 on the vestibular system
The effects of COVID-19 on the vestibular system Open
Introduction The symptoms and severity of SARS-CoV-2 infection vary greatly across the spectrum, from asymptomatic infection to severe pneumonia with acute respiratory distress syndrome and even death. Dizziness is a frequently reported sy…
View article: Acute Onset of Tinnitus in Patients with Sudden Deafness
Acute Onset of Tinnitus in Patients with Sudden Deafness Open
Objective: We made hypotheses that tinnitus will appear more likely in patients with sudden deafness with superior hearing in unaffected ear or with more severe acute hearing loss. Methods: A retrospective cohort study was performed. Five …
View article: About the pathophysiology of acute unilateral vestibular deficit – vestibular neuritis (VN) or peripheral vestibulopathy (PVP)?
About the pathophysiology of acute unilateral vestibular deficit – vestibular neuritis (VN) or peripheral vestibulopathy (PVP)? Open
OBJECTIVE: To determine whether patients with acute unilateral peripheral vestibulopathy (PVP), often called “vestibular neuritis/neuronitis or neuropathy” (VN) have a vestibular lesion pattern consistent with the distribution of the neuro…