Samuel Kaiser
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View article: Multivariate Trajectories of Weight and Mental Health and Their Prognostic Significance 6 Years After Obesity Surgery
Multivariate Trajectories of Weight and Mental Health and Their Prognostic Significance 6 Years After Obesity Surgery Open
Objective Obesity surgery (OS) results in substantial, albeit heterogeneous, long‐term improvements in weight and mental health, with unclear trajectories and their associations. This study examined multivariate trajectories of weight, psy…
View article: Poloxamer-enhanced solubility of griseofulvin and its related antifungal activity against Trichophyton spp.
Poloxamer-enhanced solubility of griseofulvin and its related antifungal activity against Trichophyton spp. Open
Poorly water-soluble drugs, such as the antifungal drug griseofulvin (GF), exhibit limited bioavailability, despite their high membrane permeability. Several technological approaches have been proposed to enhance the water solubility and b…
View article: Poloxamer-enhanced solubility of griseofulvin and its related antifungal activity against Trichophyton spp.
Poloxamer-enhanced solubility of griseofulvin and its related antifungal activity against Trichophyton spp. Open
Poorly water-soluble drugs, such as the antifungal drug griseofulvin (GF), exhibit limited bioavailability, despite their high membrane permeability. Several technological approaches have been proposed to enhance the water solubility and b…
View article: In Vitro additive effect on griseofulvin and terbinafine combinations against multidrug-resistant dermatophytes
In Vitro additive effect on griseofulvin and terbinafine combinations against multidrug-resistant dermatophytes Open
Griseofulvin (GF) and terbinafine (TF) are commonly used drugs to treat dermatophytosis, a fungal infection of the skin. Today there is an increase in drug resistance to these antifungals which highlight the need for alternative synergisti…
View article: Chemosensory aerosol assessment of key attributes for tobacco products
Chemosensory aerosol assessment of key attributes for tobacco products Open
Human sensory evaluation plays an important role in assessing quality and supports commercial product development in many industries. However, sensory evaluation of tobacco products often requires highly trained specialists, is thus expens…
View article: Stability-Indicating HPLC Method for isoflavones aglycones analysis from Trifolium pratense L. extract
Stability-Indicating HPLC Method for isoflavones aglycones analysis from Trifolium pratense L. extract Open
The purpose of this study was to develop and validate a fast HPLC stability-indicating method for simultaneously quantifying the four main isoflavones in Trifolium pratense. Validation procedures followed the ICH requirements for complex m…
View article: In Vitro additive effect on griseofulvin and terbinafine combinations against multidrug-resistant dermatophytes
In Vitro additive effect on griseofulvin and terbinafine combinations against multidrug-resistant dermatophytes Open
Griseofulvin (GF) and terbinafine (TF) are commonly used drugs to treat dermatophytosis, a fungal infection of the skin. Today there is an increase in drug resistance to these antifungals which highlight the need for alternative synergisti…
View article: <i>In vitro</i> synergism of a water insoluble fraction of <i>Uncaria tomentosa</i> combined with fluconazole and terbinafine against resistant non- <i>Candida albicans</i> isolates
<i>In vitro</i> synergism of a water insoluble fraction of <i>Uncaria tomentosa</i> combined with fluconazole and terbinafine against resistant non- <i>Candida albicans</i> isolates Open
DSC and infrared analysis demonstrated intermolecular interactions between WIF and either TRB or FLZ. Hence, quite likely the synergistic effect is related to interaction events occurring outside the cell wall between antifungal and cat's …