Stefan Louw
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View article: Antimicrobial potential of the endophytic actinobacteria isolated from Harpagophytum procumbens: A southern African medicinal plant
Antimicrobial potential of the endophytic actinobacteria isolated from Harpagophytum procumbens: A southern African medicinal plant Open
Endophytic actinobacteria associated with ethnobotanical medicinal plants are key reservoirs for the discovery of novel biomolecules and enzyme activities. The knowledge of such endophytic actinobacteria in the Southern Africa arid regions…
View article: In vitro antimalarial properties and chemical composition of Diospyros chamaethamnus extracts
In vitro antimalarial properties and chemical composition of Diospyros chamaethamnus extracts Open
Diospyros chamaethamnus, a low woody perennial, which is endemic to Namibia, Botswana, Angola, and Zambia, is used in the management of malaria. The current study aimed to assess the effectiveness of this plant against malaria parasites an…
View article: Antioxidant and DNA damage protective activities of selected endophytic actinobacteria isolated from Harpagophytum procumbens: A Kalahari desert-adapted plant
Antioxidant and DNA damage protective activities of selected endophytic actinobacteria isolated from Harpagophytum procumbens: A Kalahari desert-adapted plant Open
Given that synthetic antioxidants are currently in use and have been demonstrated to have known negative side effects, it is important to look for natural antioxidant sources. Endophytic actinobacteria, especially those associated with med…
View article: In vitro acetylcholinesterase inhibitory activity and chemical composition of the dichloromethane extracts of the leaves and inflorescences of the tumbleweed, Trachyandra laxa (N.E.Br.) Oberm. var. rigida (Suesseng.) Roessl
In vitro acetylcholinesterase inhibitory activity and chemical composition of the dichloromethane extracts of the leaves and inflorescences of the tumbleweed, Trachyandra laxa (N.E.Br.) Oberm. var. rigida (Suesseng.) Roessl Open
Trachyandra laxa, which belongs to the family Asphodelaceae, is a poisonous geophyte, often consumed by
\nlivestock, particularly when pastures are poor. Ingestion of T. laxa by livestock causes paresis and paralysis of
\nthe animals. Howe…
View article: Recent trends in the chromatographic analysis of volatile flavor and fragrance compounds: Annual review 2020
Recent trends in the chromatographic analysis of volatile flavor and fragrance compounds: Annual review 2020 Open
The chromatographic analysis of volatile flavor and fragrance compounds is performed routinely in several industries and in many fields of scientific research. Typical applications include food‐, environmental‐, essential oil‐ and cosmetic…
View article: Synthesis and In Vitro Antiprotozoan Evaluation of 4-/8-Aminoquinoline-based Lactams and Tetrazoles
Synthesis and In Vitro Antiprotozoan Evaluation of 4-/8-Aminoquinoline-based Lactams and Tetrazoles Open
A second generation of 4-aminoquinoline- and 8-aminoquinoline-based tetrazoles and lactams were synthesized via the Staudinger and Ugi multicomponent reactions. These compounds were subsequently evaluated in vitro for their potential antip…
View article: Halogenated monoterpenes from Namibian Plocamium rigidum: Accurate quantification and chemotaxonomic relevance
Halogenated monoterpenes from Namibian Plocamium rigidum: Accurate quantification and chemotaxonomic relevance Open
Recently, a Namibian Plocamium specimen that shares the characteristics of both P. suhrii and P. rigidum was described in terms of the chemistry of its secondary metabolite constituents. Three variants or forms of this species with similar…
View article: Gas Chromatography-Mass Spectrometry (GC-MS) Combined with Retention Index Prediction for the Rapid Identification of Halogenated monoterpenes from a Namibian <i>Plocamium</i> species
Gas Chromatography-Mass Spectrometry (GC-MS) Combined with Retention Index Prediction for the Rapid Identification of Halogenated monoterpenes from a Namibian <i>Plocamium</i> species Open
Plocamium species collected from the Namibian coast display morphological features similar to those of both P. rigidum and P. suhrii which makes identification of these species a difficult task. It has been reported that the major secondar…
View article: The isolation, structural determination and bioactivity of 1E,3R,4S,5E,7Z-1-bromo 3,4,8-trichloro-7- (dichloromethyl)-3-methylocta-1,5,7-triene from a Namibian Plocamium species
The isolation, structural determination and bioactivity of 1E,3R,4S,5E,7Z-1-bromo 3,4,8-trichloro-7- (dichloromethyl)-3-methylocta-1,5,7-triene from a Namibian Plocamium species Open
A known compound namely 1E,3R,4S,5E,7Z-1-bromo-3,4,8-trichloro-7-
\n(dichloromethyl)-3-methylocta-1,5,7-triene was isolated from a Namibian Plocamium
\nspecies for the first time and characterized by means of one and two dimensional
\nNucl…
View article: Enabling grassroots innovation by youth in Cape Town's townships
Enabling grassroots innovation by youth in Cape Town's townships Open
Grassroots innovation has been recognized as a valuable means to empower local communities to address developmental issues. Enabling youth in townships to solve local problems is of particular interest in South Africa due to the poor socio…