Stefania Cesa
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View article: Comparative Profiling of Volatile Compounds and Fatty Acids in Pomegranate Seed Oil: Soxhlet vs. CO2/IPA Extraction for Quality and Circular Bioeconomy Goals
Comparative Profiling of Volatile Compounds and Fatty Acids in Pomegranate Seed Oil: Soxhlet vs. CO2/IPA Extraction for Quality and Circular Bioeconomy Goals Open
This study compares the chemical profiles of pomegranate seed oil (PSO) from two cultivars, Granato (G) and Roce (R), extracted by Soxhlet and supercritical CO2/isopropanol. GC-MS and NMR analyses confirmed punicic acid as the dominant fat…
View article: Ripening-Related Changes in Color and Bioactive Compounds of Diospyros kaki: Preliminary Insights on Its Antifungal Activity
Ripening-Related Changes in Color and Bioactive Compounds of Diospyros kaki: Preliminary Insights on Its Antifungal Activity Open
Diospyros kaki L. is acknowledged for its extraordinary phytotherapeutic properties due to the presence of polyphenols, carotenoids, and flavonoids such as β-cryptoxanthin and rutin. These compounds are largely distributed in the skin and …
View article: The anthocyanin‐enriched extract of <i>Vaccinium corymbosum</i> exerted in vitro and ex vivo antiproliferative and anti‐inflammatory activities
The anthocyanin‐enriched extract of <i>Vaccinium corymbosum</i> exerted in vitro and ex vivo antiproliferative and anti‐inflammatory activities Open
Background Vaccinium corymbosum berries represent a source of anthocyanins and polyphenols studied and tested for their healthy potential. The present study was aimed at isolating, characterizing, and quantifying the anthocyanin‐enriched f…
View article: Pomegranate Juices: Analytical and Bio-Toxicological Comparison of Pasteurization and High-Pressure Processing in the Development of Healthy Products
Pomegranate Juices: Analytical and Bio-Toxicological Comparison of Pasteurization and High-Pressure Processing in the Development of Healthy Products Open
Two different produced and packaged commercial typologies of pomegranate juice were analyzed for their physicochemical, nutritional, and biological properties. The effects of classical pasteurization (PJ) and high-pressure processing (HP),…
View article: Valorisation of Side Stream Products through Green Approaches: The Rapeseed Meal Case
Valorisation of Side Stream Products through Green Approaches: The Rapeseed Meal Case Open
Rapeseed meal (RSM) is a by-product of rapeseed oil extraction and is a rich source of bioactive compounds, including proteins and antioxidants. This study compared two methods for extracting antioxidants from RSM: conventional ethanol Sox…
View article: Dual delivery of ginger oil and hexylresorcinol with lipid nanoparticles for the effective treatment of cutaneous hyperpigmentation
Dual delivery of ginger oil and hexylresorcinol with lipid nanoparticles for the effective treatment of cutaneous hyperpigmentation Open
Cutaneous hyperpigmentation is a widespread pathology affecting a large slice of the world population. In this work, we propose a treatment approach based on the co-delivery of 4-hexylresorcinol (HR) and ginger oil (GO), using lipid nanopa…
View article: Pomegranate Fruit Cracking during Maturation: From Waste to Valuable Fruits
Pomegranate Fruit Cracking during Maturation: From Waste to Valuable Fruits Open
The pomegranate is an emerging functional food which is nowadays becoming more and more commercially attractive. Each part of this fruit (peels, arils and seeds) has a specific phytocomplex, rich in anti-oxidant and anti-radical compounds.…
View article: In-Depth Chemical Characterization of Punica granatum L. Seed Oil
In-Depth Chemical Characterization of Punica granatum L. Seed Oil Open
Fruit seeds belonging to the pomegranate cultivar “Granata” were subjected to extraction and oily component analysis, with the aim of obtaining information about their composition. The presence of conjugated isomers of linolenic acid (CLNA…
View article: Antibiofilm activity and NMR-based metabolomic characterization of cell-free supernatant of Limosilactobacillus reuteri DSM 17938
Antibiofilm activity and NMR-based metabolomic characterization of cell-free supernatant of Limosilactobacillus reuteri DSM 17938 Open
The microbial biofilm has been defined as a “key virulence factor” for a multitude of microorganisms associated with chronic infections. Its multifactorial nature and variability, as well as an increase in antimicrobial resistance, suggest…
View article: Effects of Processing on Chemical Composition of Extracts from Sour Cherry Fruits, a Neglected Functional Food
Effects of Processing on Chemical Composition of Extracts from Sour Cherry Fruits, a Neglected Functional Food Open
Sour cherries fruits (Prunus cerasus L., syn P. cerasus var. austera) are locally known as “visciola di Sezze”, due to the name of the city where they are traditionally cultivated in Lazio Region, Italy. Fruit samples from three harvesting…
View article: Anti-Inflammatory and Antioxidant Effects Induced by Allium sativum L. Extracts on an Ex Vivo Experimental Model of Ulcerative Colitis
Anti-Inflammatory and Antioxidant Effects Induced by Allium sativum L. Extracts on an Ex Vivo Experimental Model of Ulcerative Colitis Open
Inflammatory bowel diseases (IBDs) are chronic and multifactorial inflammatory conditions of the colonic mucosa (ulcerative colitis), characterized by increased and unbalanced immune response to external stimuli. Garlic and its bioactive c…
View article: Characterization and Valorization of ‘Sulmona Red Garlic’ Peels and Small Bulbs
Characterization and Valorization of ‘Sulmona Red Garlic’ Peels and Small Bulbs Open
‘Sulmona red garlic’ is an Italian variety characterized by a red tunica surrounding a white bulb. Red tunicae and non-commercial small bulbs are food wastes that must be studied for their added value. Hydroalcoholic extracts, obtained by …
View article: Protective Effects of PollenAid Plus Soft Gel Capsules’ Hydroalcoholic Extract in Isolated Prostates and Ovaries Exposed to Lipopolysaccharide
Protective Effects of PollenAid Plus Soft Gel Capsules’ Hydroalcoholic Extract in Isolated Prostates and Ovaries Exposed to Lipopolysaccharide Open
Pollen extract represents an innovative approach for the management of the clinical symptoms related to prostatitis and pelvic inflammatory disease (PID). In this context, the aims of the present work were to analyze the phenolic compositi…
View article: Solvent Casting and UV Photocuring for Easy and Safe Fabrication of Nanocomposite Film Dressings
Solvent Casting and UV Photocuring for Easy and Safe Fabrication of Nanocomposite Film Dressings Open
The aim of this work was to optimize and characterize nanocomposite films based on gellan gum methacrylate (GG-MA) and silver nanoparticles (AgNPs) for application in the field of wound dressing. The films were produced using the solvent c…
View article: Valorization of Kiwi Peels: Fractionation, Bioactives Analyses and Hypotheses on Complete Peels Recycle
Valorization of Kiwi Peels: Fractionation, Bioactives Analyses and Hypotheses on Complete Peels Recycle Open
Kiwi fruit samples (Actinidia deliciosa Planch, cv. Hayward) represent a suitable and good source for fibers obtainment as well as for polyphenolic and carotenoid extraction. With this aim, in this study they were submitted to a double pha…
View article: Development of an Optimized Drying Process for the Recovery of Bioactive Compounds from the Autumn Fruits of Berberis vulgaris L. and Crataegus monogyna Jacq.
Development of an Optimized Drying Process for the Recovery of Bioactive Compounds from the Autumn Fruits of Berberis vulgaris L. and Crataegus monogyna Jacq. Open
Hot air drying has proven to be an efficient method to preserve specific edible plant materials with medicinal properties. This is a process involving chemical, physical, and biological changes in plant matrices. Understanding these proces…
View article: Injectable and In Situ Gelling Dextran Derivatives Containing Hydrolyzable Groups for the Delivery of Large Molecules
Injectable and In Situ Gelling Dextran Derivatives Containing Hydrolyzable Groups for the Delivery of Large Molecules Open
Recently, we reported the synthesis and characterization of a new dextran derivative obtained by grafting polyethylene glycol methacrylate to a polysaccharide backbone through a carbonate bond. This moiety was introduced because it allows …
View article: Study on Extra Virgin Olive Oil: Quality Evaluation by Anti-Radical Activity, Color Analysis, and Polyphenolic HPLC-DAD Analysis
Study on Extra Virgin Olive Oil: Quality Evaluation by Anti-Radical Activity, Color Analysis, and Polyphenolic HPLC-DAD Analysis Open
This study aimed to evaluate the quality of oils available on the Italian market and purchased directly from the mill or in the supermarket and labelled as extra virgin olive oils (EVOOs). As one of the most relevant foods of the Mediterra…
View article: Protective Effects Induced by a Hydroalcoholic Allium sativum Extract in Isolated Mouse Heart
Protective Effects Induced by a Hydroalcoholic Allium sativum Extract in Isolated Mouse Heart Open
The aim of the present study was to investigate the possible protective effects of a garlic hydroalcoholic extract on the burden of oxidative stress and inflammation occurring on mouse heart specimens exposed to E. coli lipopolysaccharide …
View article: Health Potential of Clery Strawberries: Enzymatic Inhibition and Anti-Candida Activity Evaluation
Health Potential of Clery Strawberries: Enzymatic Inhibition and Anti-Candida Activity Evaluation Open
Strawberries, belonging to cultivar Clery (Fragaria × ananassa Duchesne ex Weston) and to a graft obtained by crossing Clery and Fragaria vesca L., were chosen for a study on their health potential, with regard to the prevention of chronic…
View article: Chemical and Bioinformatics Analyses of the Anti-Leishmanial and Anti-Oxidant Activities of Hemp Essential Oil
Chemical and Bioinformatics Analyses of the Anti-Leishmanial and Anti-Oxidant Activities of Hemp Essential Oil Open
Industrial hemp is a multiuse crop that has been widely cultivated to produce fibers and nutrients. The capability of the essential oil (EO) from inflorescences as antimicrobial agent has been reported. However, literature data are still l…
View article: Optimization of the drying process of autumn fruits rich in antioxidants: a study focusing on rosehip (<i>Rosa canina</i> L.) and sea buckthorn (<i>Elaeagnus rhamnoides</i> (L.) A. Nelson) and their bioactive properties
Optimization of the drying process of autumn fruits rich in antioxidants: a study focusing on rosehip (<i>Rosa canina</i> L.) and sea buckthorn (<i>Elaeagnus rhamnoides</i> (L.) A. Nelson) and their bioactive properties Open
The main goal of our work was to establish the optimal parameters for the drying process of rosehip and sea buckthorn fruits, in order to enhance the recovery of bioactive compounds from these vegetal matrices.
View article: Commercial Hemp Seed Oils: A Multimethodological Characterization
Commercial Hemp Seed Oils: A Multimethodological Characterization Open
Nine commercial hemp seed oils from different countries were studied using a multimethodological approach to obtain information about their quality and chemical composition. Due to the lack of a specific regulation for hemp seed oils, qual…
View article: Effects of Processing on Polyphenolic and Volatile Composition and Fruit Quality of Clery Strawberries
Effects of Processing on Polyphenolic and Volatile Composition and Fruit Quality of Clery Strawberries Open
Strawberries belonging to cultivar Clery (Fragaria x ananassa (Duchesne ex Weston)), cultivated in central Italy were subjected to a multi-methodological experimental study. Fresh and defrosted strawberries were exposed to different proces…
View article: Water Extract from Inflorescences of Industrial Hemp Futura 75 Variety as a Source of Anti-Inflammatory, Anti-Proliferative and Antimycotic Agents: Results from In Silico, In Vitro and Ex Vivo Studies
Water Extract from Inflorescences of Industrial Hemp Futura 75 Variety as a Source of Anti-Inflammatory, Anti-Proliferative and Antimycotic Agents: Results from In Silico, In Vitro and Ex Vivo Studies Open
Industrial hemp (Cannabis sativa) is traditionally cultivated as a valuable source of fibers and nutrients. Multiple studies also demonstrated antimicrobial, anti-proliferative, phytotoxic and insecticide effects of the essential oil from …