Stefania Greco
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View article: 3D-Printed Alginate-Based Hydrogels with Appropriate Rheological Properties and Efficient Development of Cell Spheroids
3D-Printed Alginate-Based Hydrogels with Appropriate Rheological Properties and Efficient Development of Cell Spheroids Open
In the last years, considerable innovation has been made regarding bioprinting, particularly in the development of cell-loaded hydrogels. The specific properties of the bioinks are crucial for printing an adequate cell-laden hydrogel struc…
View article: Endothelial cell alterations in capillaries of adipose tissue from patients affected by lipedema
Endothelial cell alterations in capillaries of adipose tissue from patients affected by lipedema Open
Objective This study aimed to evaluate adipose tissue of lipedema patients. Methods Gluteo‐femoral (affected area) and interscapular (nonaffected area) adipose tissue from 10 lean patients affected by lipedema stage 1 to 2 was studied and …
View article: Raf kinase inhibitor protein expression in smooth muscle tumours of the uterus: a diagnostic marker for leiomyosarcoma?
Raf kinase inhibitor protein expression in smooth muscle tumours of the uterus: a diagnostic marker for leiomyosarcoma? Open
RKIP distinct expression pattern among leiomyoma histotype and leiomyosarcoma, and its effect on leiomyosarcoma cells on colony formation, encourages further studies of RKIP in uterine smooth muscle disorders.
View article: Impact of Nutrition on Female Reproductive Disorders
Impact of Nutrition on Female Reproductive Disorders Open
The female reproductive system is a delicate and complex system in the body that can be affected by many disorders [...]
View article: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells
The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells Open
Leiomyosarcoma is an aggressive soft tissue sarcoma derived from the smooth muscle cells of the uterus. We tested the effect of Romina strawberry extract treatment on three-dimensional cultured uterine leiomyosarcoma cells. We established …
View article: High levels of hypusinated eIF5A in leiomyoma and leiomyosarcoma pathologies: a possible novel therapeutic target
High levels of hypusinated eIF5A in leiomyoma and leiomyosarcoma pathologies: a possible novel therapeutic target Open
These data support the hypothesis that eIF5A may be involved in the pathogenesis of myometrial benign and malignant pathologies.
View article: From Survey Results to a Decision-Making Matrix for Strategic Planning in Healthcare: The Case of Clinical Pathways
From Survey Results to a Decision-Making Matrix for Strategic Planning in Healthcare: The Case of Clinical Pathways Open
Background: It is a well-known fact that the information obtained from a survey can be used in a healthcare organizational analysis; however, it is very difficult to compare the different results found in the literature to each other, even…
View article: Impact of the COVID-19 Pandemic on Clinical Pathways for Non-SARS-CoV-2 Related Diseases in the Lazio Region, Italy
Impact of the COVID-19 Pandemic on Clinical Pathways for Non-SARS-CoV-2 Related Diseases in the Lazio Region, Italy Open
Clinical pathways (CPs) are multidisciplinary clinical governance tools necessary for the care management of the patients, whose aim is to outline the best practicable path within a health organization related to an illness or to a complex…
View article: Phytoprogestins: Unexplored Food Compounds with Potential Preventive and Therapeutic Effects in Female Diseases
Phytoprogestins: Unexplored Food Compounds with Potential Preventive and Therapeutic Effects in Female Diseases Open
In recent years, there has been an increasing interest in natural therapies to prevent or treat female diseases. In particular, many studies have focused on searching natural compounds with less side effects than standard hormonal therapie…
View article: Hop and artichoke extracts inhibit expression of extracellular matrix components in uterine leiomyoma cells
Hop and artichoke extracts inhibit expression of extracellular matrix components in uterine leiomyoma cells Open
These results suggest that the hop and artichoke extracts possess antifibrotic properties and support additional evaluation using in vivo models.
View article: Macrophages and Immune Responses in Uterine Fibroids
Macrophages and Immune Responses in Uterine Fibroids Open
Uterine fibroids represent the most common benign tumors of the uterus. They are considered a typical fibrotic disorder. In fact, the extracellular matrix (ECM) proteins—above all, collagen 1A1, fibronectin and versican—are upregulated in …
View article: Management of locally advanced non-small cell lung cancer in the modern era: A national Italian survey on diagnosis, treatment and multidisciplinary approach
Management of locally advanced non-small cell lung cancer in the modern era: A national Italian survey on diagnosis, treatment and multidisciplinary approach Open
Concurrent chemotherapy and radiotherapy (cCRT) is considered the standard treatment of locally advanced non-small cell lung cancer (LA-NSCLC). Unfortunately, management is still heterogeneous across different specialists. A multidisciplin…
View article: Advanced 3D Imaging of Uterine Leiomyoma’s Morphology by Propagation-based Phase-Contrast Microtomography
Advanced 3D Imaging of Uterine Leiomyoma’s Morphology by Propagation-based Phase-Contrast Microtomography Open
Uterine leiomyoma is the most common benign smooth muscle tumor in women pelvis, originating from the myometrium. It is caused by a disorder of fibrosis, with a large production and disruption of extracellular matrix (ECM). Medical treatme…
View article: Prophylactic Dermatologic Treatment of Afatinib-Induced Skin Toxicities in Patients with Metastatic Lung Cancer: A Pilot Study
Prophylactic Dermatologic Treatment of Afatinib-Induced Skin Toxicities in Patients with Metastatic Lung Cancer: A Pilot Study Open
Background . Severe skin rash is listed among important side effects of EGFR tyrosine kinase inhibitors. Polydatin (PD), a glycosylated polyphenol, is endowed with anti-inflammatory activity in human epidermal keratinocytes. Objective . Th…
View article: Romina: A powerful strawberry with in vitro efficacy against uterine leiomyoma cells
Romina: A powerful strawberry with in vitro efficacy against uterine leiomyoma cells Open
Uterine leiom yomas are benign tumors highly prevalent in reproductive women. In thecurrent study, initially, we aimed to screen five different strawberry cultivars (Alba, Clery, Portola, Tecla, and Romina) to identify efficient cultivars …
View article: Raf Kinase Inhibitor Protein (RKIP) expression and function in human myometrium and leiomyoma
Raf Kinase Inhibitor Protein (RKIP) expression and function in human myometrium and leiomyoma Open
Many growth factors been identified in human myometrium and leiomyoma and activate multiple signaling pathways in order to regulate major cellular processes, including proliferation and fibrosis which are linked to uterine leiomyoma develo…
View article: An anthocyanin rich strawberry extract induces apoptosis and ROS while decreases glycolysis and fibrosis in human uterine leiomyoma cells
An anthocyanin rich strawberry extract induces apoptosis and ROS while decreases glycolysis and fibrosis in human uterine leiomyoma cells Open
Uterine leiomyomas are highly prevalent benign tumors in reproductive aged women. Unfortunately, medical treatments are still limited and no preventive therapies have been developed. In the present study, we investigated the therapeutic ef…