Stefania Paolillo
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View article: Adherence to guideline‐directed medical treatments in heart failure. A scientific statement of the Heart Failure Association ( <scp>HFA</scp> ) of the <scp>ESC</scp> and the <scp>ESC</scp> Working Group on Cardiovascular Pharmacotherapy
Adherence to guideline‐directed medical treatments in heart failure. A scientific statement of the Heart Failure Association ( <span>HFA</span> ) of the <span>ESC</span> and the <span>ESC</span> Working Group on Cardiovascular Pharmacotherapy Open
Heart failure (HF) affects over 60 million individuals globally. Contemporary guideline‐directed medical therapies (GDMT) reduce cardiovascular mortality and HF hospitalizations. However, medication non‐adherence represents a critical barr…
View article: Heart failure and chronic obstructive pulmonary disease. A combination not to be underestimated
Heart failure and chronic obstructive pulmonary disease. A combination not to be underestimated Open
View article: SIRM/SIC consensus document on the management of patients with acute chest pain
SIRM/SIC consensus document on the management of patients with acute chest pain Open
Acute chest pain is a common and challenging reason for emergency department visits and requires prompt and systematic evaluation to address potential life-threatening conditions, minimize risks and manage emergency department overcrowding…
View article: Lung ultrasound in cardiac rehabilitation: expert consensus on protocols, clinical use, and integration into patient management from the working group on cardiac rehabilitation and cardiovascular prevention of the Italian society of cardiology
Lung ultrasound in cardiac rehabilitation: expert consensus on protocols, clinical use, and integration into patient management from the working group on cardiac rehabilitation and cardiovascular prevention of the Italian society of cardiology Open
Lung ultrasonography (LUS) is a reliable and reproducible tool across various clinical settings. Its high diagnostic accuracy, portability, and real-time imaging capabilities make it especially suitable for use in Emergency Departments, In…
View article: Gender and Sex-related differences in Type 2 Myocardial Infarction: the undervalued side of a neglected disease
Gender and Sex-related differences in Type 2 Myocardial Infarction: the undervalued side of a neglected disease Open
Type 2 myocardial infarction (T2MI) occurs due to an imbalance between coronary blood supply and myocardial oxygen demand, leading to ischemia without the rupture of an atherosclerotic plaque, distinguishing it from Type 1 myocardial infar…
View article: Circulating miR-10b-5p, miR-193a-3p, and miR-1-3p Are Deregulated in Patients with Heart Failure and Correlate with Hormonal Deficiencies
Circulating miR-10b-5p, miR-193a-3p, and miR-1-3p Are Deregulated in Patients with Heart Failure and Correlate with Hormonal Deficiencies Open
Heart failure (HF) is among the most important causes of worldwide morbidity, hospitalisation, and mortality. A reduction in anabolic hormonal axes seems to potentially play an important role in chronic HF progression and prognosis. Severa…
View article: Growth hormone replacement therapy in heart failure with reduced ejection fraction: a randomized, double-blind, placebo-controlled trial
Growth hormone replacement therapy in heart failure with reduced ejection fraction: a randomized, double-blind, placebo-controlled trial Open
Background Preliminary results of GH deficiency (GHD) correction in Heart Failure (HF) showed an improvement in quality of life, cardiac architecture and function, and cardiovascular performance. Aim of the present double-blind, randomized…
View article: Therapeutic tailored approach in patients with diabetes, cardiovascular and renal comorbidities: A cardiologist's view
Therapeutic tailored approach in patients with diabetes, cardiovascular and renal comorbidities: A cardiologist's view Open
Lowering the likelihood of CV accidents becomes a crucial objective in addition to glucose management. A multimodal management is the priority to counteract micro- and macrovascular complications of T2DM and reduce associated morbidity and…
View article: Quality of life in heart failure. The heart of the matter. A scientific statement of the Heart Failure Association and the <scp>European Association of Preventive Cardiology</scp> of the <scp>European Society of Cardiology</scp>
Quality of life in heart failure. The heart of the matter. A scientific statement of the Heart Failure Association and the <span>European Association of Preventive Cardiology</span> of the <span>European Society of Cardiology</span> Open
For most patients with chronic, progressive illnesses, maintaining good quality of life (QoL), with preserved functional capacity, is just as crucial as prolonging survival. Patients with heart failure (HF) experience much worse QoL and ef…
View article: Growth Hormone Replacement Therapy in Heart Failure With Reduced Ejection Fraction
Growth Hormone Replacement Therapy in Heart Failure With Reduced Ejection Fraction Open
This randomized, double-blind, placebo-controlled trial demonstrates that GH replacement therapy in HFrEF patients with GHD improves exercise performance, and left ventricular and right ventricular structure and function, leading to an ame…
View article: ANOCA, INOCA, MINOCA: The New Frontier of Coronary Syndromes
ANOCA, INOCA, MINOCA: The New Frontier of Coronary Syndromes Open
The growing prevalence in the diagnosis of INOCA (Ischemia with Non-Obstructive Coronary Arteries), ANOCA (Angina with Non-Obstructive Coronary Arteries), and MINOCA (Myocardial Infarction with Non-Obstructive Coronary Arteries) highlights…
View article: Implementation of guideline‐directed medical therapy in patients with heart failure with reduced ejection fraction (OpTIMa‐HF Registry)
Implementation of guideline‐directed medical therapy in patients with heart failure with reduced ejection fraction (OpTIMa‐HF Registry) Open
Aims The last released European guidelines on the management of heart failure (HF) recommend in patients with chronic HF with reduced ejection fraction (HFrEF) a pharmacological approach based on four fundamental drugs to be rapidly implem…
View article: Advancing Cardiovascular Diagnostics: The Expanding Role of CMR in Heart Failure and Cardiomyopathies
Advancing Cardiovascular Diagnostics: The Expanding Role of CMR in Heart Failure and Cardiomyopathies Open
Cardiovascular magnetic resonance (CMR) imaging has become a cornerstone in the diagnosis, risk stratification, and management of cardiovascular disease (CVD), particularly heart failure (HF) and cardiomyopathies. Renowned as the gold stan…
View article: Biomarkers for Congestion in Heart Failure: State-of-the-art and Future Directions
Biomarkers for Congestion in Heart Failure: State-of-the-art and Future Directions Open
Congestion in patients with heart failure (HF) predicts adverse outcomes and is a leading cause of hospitalisation. Understanding congestion mechanisms helps in HF management and underscores the importance of tailored therapies to treat va…
View article: Editorial: Cardiac reverse remodeling after novel heart failure therapies—volume II
Editorial: Cardiac reverse remodeling after novel heart failure therapies—volume II Open
View article: Heart failure outpatient clinics resources in Italy: a viewpoint of Italian Society of Cardiology organization
Heart failure outpatient clinics resources in Italy: a viewpoint of Italian Society of Cardiology organization Open
View article: Current trends and challenges in the clinical use of cardiovascular magnetic resonance: a survey from the Italian Society of Cardiology
Current trends and challenges in the clinical use of cardiovascular magnetic resonance: a survey from the Italian Society of Cardiology Open
Aims Challenges related to the use of cardiovascular magnetic resonance (CMR) remain a key issue to secure its full clinical impact. This survey aimed to assess the awareness of CMR clinical utility and to collect data on its local usage l…
View article: A Personalized Approach to Vitamin D Supplementation in Cardiovascular Health Beyond the Bone: An Expert Consensus by the Italian National Institute for Cardiovascular Research
A Personalized Approach to Vitamin D Supplementation in Cardiovascular Health Beyond the Bone: An Expert Consensus by the Italian National Institute for Cardiovascular Research Open
Vitamin D is increasingly recognized for its role in cardiovascular health beyond its well-established effects on bone metabolism. This review synthesizes findings from observational studies, interventional trials, and meta-analyses to cla…
View article: Update on the diagnosis and treatment of pericardial diseases: a position paper of the Italian Society of Cardiology in collaboration with the study group on cardiomyopathies and pericardial diseases
Update on the diagnosis and treatment of pericardial diseases: a position paper of the Italian Society of Cardiology in collaboration with the study group on cardiomyopathies and pericardial diseases Open
The knowledge of pericardial diseases has now improved, including prospective and retrospective cohort studies focusing on the pathogenesis, diagnosis, treatment, and outcomes. The complex interplay between genetic predisposition (especial…
View article: Cardiovascular disease and psychiatric disorders: An-up-to date review
Cardiovascular disease and psychiatric disorders: An-up-to date review Open
Cardiovascular diseases (CVD) and mental health disorders (MHD) are respectively the first and second most prevalent diseases in high-income countries and the two most relevant causes of disability worldwide. The close association between …
View article: The chronic heart failure evolutions: Different fates and routes
The chronic heart failure evolutions: Different fates and routes Open
Aims Individual prognostic assessment and disease evolution pathways are undefined in chronic heart failure (HF). The application of unsupervised learning methodologies could help to identify patient phenotypes and the progression in each …
View article: Artificial intelligence in cardiology: a peek at the future and the role of ChatGPT in cardiology practice
Artificial intelligence in cardiology: a peek at the future and the role of ChatGPT in cardiology practice Open
Artificial intelligence has increasingly become an integral part of our daily activities. ChatGPT, a natural language processing technology developed by OpenAI, is widely used in various industries, including healthcare. The application of…
View article: Crosslink between atrial fibrillation and cancer: a therapeutic conundrum
Crosslink between atrial fibrillation and cancer: a therapeutic conundrum Open
View article: Correction: Subclinical hypothyroidism predicts outcome in heart failure: insights from the T.O.S.CA. registry
Correction: Subclinical hypothyroidism predicts outcome in heart failure: insights from the T.O.S.CA. registry Open
View article: A matter of sex—persistent predictive value of MECKI score prognostic power in men and women with heart failure and reduced ejection fraction: a multicenter study
A matter of sex—persistent predictive value of MECKI score prognostic power in men and women with heart failure and reduced ejection fraction: a multicenter study Open
Background A sex-based evaluation of prognosis in heart failure (HF) is lacking. Methods and results We analyzed the Metabolic Exercise test data combined with Cardiac and Kidney Indexes (MECKI) score registry, which includes HF with reduc…
View article: Hypertriglyceridemia: Molecular and Genetic Landscapes
Hypertriglyceridemia: Molecular and Genetic Landscapes Open
Lipid disorders represent one of the most worrisome cardiovascular risk factors. The focus on the impact of lipids on cardiac and vascular health usually concerns low-density lipoprotein cholesterol, while the role of triglycerides (TGs) i…
View article: Subclinical hypothyroidism predicts outcome in heart failure: insights from the T.O.S.CA. registry
Subclinical hypothyroidism predicts outcome in heart failure: insights from the T.O.S.CA. registry Open
View article: Novel Strategies in Diagnosing Heart Failure with Preserved Ejection Fraction: A Comprehensive Literature Review
Novel Strategies in Diagnosing Heart Failure with Preserved Ejection Fraction: A Comprehensive Literature Review Open
Heart failure (HF) with preserved ejection fraction (HFpEF) is a prevalent global condition affecting approximately 50% of the HF population. With the aging of the worldwide population, its incidence and prevalence are expected to rise eve…
View article: Exploring the Prognostic Performance of MECKI Score in Heart Failure Patients with Non-Valvular Atrial Fibrillation Treated with Edoxaban
Exploring the Prognostic Performance of MECKI Score in Heart Failure Patients with Non-Valvular Atrial Fibrillation Treated with Edoxaban Open
Introduction: Risk stratification in heart failure (HF) is essential for clinical and therapeutic management. The Metabolic Exercise test data combined with Cardiac and Kidney Indexes (MECKI) score is a validated prognostic model for asses…
View article: Efficacy and safety of inclisiran in real world practice: insights from the Cholinet registry
Efficacy and safety of inclisiran in real world practice: insights from the Cholinet registry Open
Background Inclisiran has been recently introduced in clinical practice. Thus, efficacy and safety data from real world settings are scarce. In Italy, reimbursement of inclisiran has been recently introduced for very high cardiovascular (C…