Stefania Petralito
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View article: Ripening-Related Changes in Color and Bioactive Compounds of Diospyros kaki: Preliminary Insights on Its Antifungal Activity
Ripening-Related Changes in Color and Bioactive Compounds of Diospyros kaki: Preliminary Insights on Its Antifungal Activity Open
Diospyros kaki L. is acknowledged for its extraordinary phytotherapeutic properties due to the presence of polyphenols, carotenoids, and flavonoids such as β-cryptoxanthin and rutin. These compounds are largely distributed in the skin and …
View article: Impact of Composition and Autoclave Sterilization on the Mechanical and Biological Properties of ECM-Mimicking Cryogels
Impact of Composition and Autoclave Sterilization on the Mechanical and Biological Properties of ECM-Mimicking Cryogels Open
Cryogels represent a valid strategy as scaffolds for tissue engineering. In order to adequately support adhesion and proliferation of anchorage-dependent cells, different polymers need to be combined within the same scaffold trying to mimi…
View article: Liposome Encapsulation of the Palmitoyl–KTTKS Peptide: Structural and Functional Characterization
Liposome Encapsulation of the Palmitoyl–KTTKS Peptide: Structural and Functional Characterization Open
In this study, the amphiphilic N-palmitoyl–KTTKS peptide was integrated in the bilayer of egg-derived phosphatidylcholine (PC) vesicles using two different preparation methods, namely thin-film evaporation (TLE) and reverse-phase evaporati…
View article: Long-Term Stability of Lavandula x intermedia Essential Oil Nanoemulsions: Can the Addition of the Ripening Inhibitor Impact the Biocidal Activity of the Nanoformulations?
Long-Term Stability of Lavandula x intermedia Essential Oil Nanoemulsions: Can the Addition of the Ripening Inhibitor Impact the Biocidal Activity of the Nanoformulations? Open
In this work, Lavandula x intermedia essential oil (LEO) was encapsulated in lipid-based nanoemulsions (NanoLEO) using the solvent-displacement technique. In order to preserve the colloidal stability of the formulation, LEO was appropriate…
View article: Cryogel Scaffolds for Tissue-Engineering: Advances and Challenges for Effective Bone and Cartilage Regeneration
Cryogel Scaffolds for Tissue-Engineering: Advances and Challenges for Effective Bone and Cartilage Regeneration Open
Critical-sized bone defects and articular cartilage injuries resulting from trauma, osteonecrosis, or age-related degeneration can be often non-healed by physiological repairing mechanisms, thus representing a relevant clinical issue due t…
View article: Advances and Challenges in Cryogel-Based Tissue Engineering for Effective Bone and Cartilage Reconstruction
Advances and Challenges in Cryogel-Based Tissue Engineering for Effective Bone and Cartilage Reconstruction Open
Critical sized bone defects and articular cartilage injuries resulting from trauma, osteonecrosis or age-related degeneration are often nonhealing by the physiological repairing mechanisms, thus representing a clinic issue due to the relev…
View article: Dual delivery of ginger oil and hexylresorcinol with lipid nanoparticles for the effective treatment of cutaneous hyperpigmentation
Dual delivery of ginger oil and hexylresorcinol with lipid nanoparticles for the effective treatment of cutaneous hyperpigmentation Open
Cutaneous hyperpigmentation is a widespread pathology affecting a large slice of the world population. In this work, we propose a treatment approach based on the co-delivery of 4-hexylresorcinol (HR) and ginger oil (GO), using lipid nanopa…
View article: Gelatin-based spongy and compressive resistant cryogels with shape recovery ability as ideal scaffolds to support cell adhesion for tissue regeneration
Gelatin-based spongy and compressive resistant cryogels with shape recovery ability as ideal scaffolds to support cell adhesion for tissue regeneration Open
Methacryloyl gelatin (GelMA) was blended with dextran methacrylate (DexMA) to produce polymer networks with interconnected macropores via cryostructuring and radical crosslinking of the polymers at subzero temperatures. The experimental se…
View article: Solvent Casting and UV Photocuring for Easy and Safe Fabrication of Nanocomposite Film Dressings
Solvent Casting and UV Photocuring for Easy and Safe Fabrication of Nanocomposite Film Dressings Open
The aim of this work was to optimize and characterize nanocomposite films based on gellan gum methacrylate (GG-MA) and silver nanoparticles (AgNPs) for application in the field of wound dressing. The films were produced using the solvent c…
View article: The Impact of Bilayer Rigidity on the Release from Magnetoliposomes Vesicles Controlled by PEMFs
The Impact of Bilayer Rigidity on the Release from Magnetoliposomes Vesicles Controlled by PEMFs Open
Stimuli-sensitive nanocarriers have recently been developed as a powerful tool in biomedical applications such as drug delivery, detection, and gene transfer techniques. Among the external triggers investigated, low intensity magnetic fiel…
View article: Injectable and In Situ Gelling Dextran Derivatives Containing Hydrolyzable Groups for the Delivery of Large Molecules
Injectable and In Situ Gelling Dextran Derivatives Containing Hydrolyzable Groups for the Delivery of Large Molecules Open
Recently, we reported the synthesis and characterization of a new dextran derivative obtained by grafting polyethylene glycol methacrylate to a polysaccharide backbone through a carbonate bond. This moiety was introduced because it allows …
View article: Study on Extra Virgin Olive Oil: Quality Evaluation by Anti-Radical Activity, Color Analysis, and Polyphenolic HPLC-DAD Analysis
Study on Extra Virgin Olive Oil: Quality Evaluation by Anti-Radical Activity, Color Analysis, and Polyphenolic HPLC-DAD Analysis Open
This study aimed to evaluate the quality of oils available on the Italian market and purchased directly from the mill or in the supermarket and labelled as extra virgin olive oils (EVOOs). As one of the most relevant foods of the Mediterra…
View article: Non -thermal electromagnetic fields to trigger drug release from high-Tm magnetoliposome
Non -thermal electromagnetic fields to trigger drug release from high-Tm magnetoliposome Open
Now a days the researches and development within the field of technology has provided a supply of novelty in numerous ground. The yields of nanoscience and nano particles aren't any exception. Nanoparticles ar merely particles within the n…
View article: Chemical Investigation and Screening of Anti-Proliferative Activity on Human Cell Lines of Pure and Nano-Formulated Lavandin Essential Oil
Chemical Investigation and Screening of Anti-Proliferative Activity on Human Cell Lines of Pure and Nano-Formulated Lavandin Essential Oil Open
Lavandin essential oil (LEO), a natural sterile hybrid obtained by crossbreeding L. angustifolia × L. latifolia, is mainly composed by active components belonging to the family of terpenes endowed with relevant anti-proliferative activity,…
View article: Enhanced Loading Efficiency and Mucoadhesion Properties of Gellan Gum Thin Films by Complexation with Hydroxypropyl-β-Cyclodextrin
Enhanced Loading Efficiency and Mucoadhesion Properties of Gellan Gum Thin Films by Complexation with Hydroxypropyl-β-Cyclodextrin Open
Polymeric oral thin films (OTFs) were prepared by the casting method, combining gellan gum (GG), a water-soluble polysaccharide, and glycerol (Gly) as a plasticizing agent. GG-Gly films were investigated as potential systems for buccal dru…
View article: Proof-of-Concept of Electrical Activation of Liposome Nanocarriers: From Dry to Wet Experiments
Proof-of-Concept of Electrical Activation of Liposome Nanocarriers: From Dry to Wet Experiments Open
The increasing interest toward biocompatible nanotechnologies in medicine, combined with electric fields stimulation, is leading to the development of electro-sensitive smart systems for drug delivery applications. To this regard, recently…
View article: Gellan Gum/Laponite Beads for the Modified Release of Drugs: Experimental and Modeling Study of Gastrointestinal Release
Gellan Gum/Laponite Beads for the Modified Release of Drugs: Experimental and Modeling Study of Gastrointestinal Release Open
In this study, gellan gum (GG), a natural polysaccharide, was used to fabricate spherical porous beads suitable as sustained drug delivery systems for oral administration. GG was cross-linked with calcium ions to prepare polymeric beads. R…
View article: SPC Liposomes as Possible Delivery Systems for Improving Bioavailability of the Natural Sesquiterpene β-Caryophyllene: Lamellarity and Drug-Loading as Key Features for a Rational Drug Delivery Design
SPC Liposomes as Possible Delivery Systems for Improving Bioavailability of the Natural Sesquiterpene β-Caryophyllene: Lamellarity and Drug-Loading as Key Features for a Rational Drug Delivery Design Open
The natural sesquiterpene β-caryophyllene (CRY) has been highlighted to possess interesting pharmacological potentials, particularly due to its chemopreventive and analgesic properties. However, the poor solubility of this sesquiterpene in…
View article: Experimental and Modeling Study of Drug Release from HPMC-Based Erodible Oral Thin Films
Experimental and Modeling Study of Drug Release from HPMC-Based Erodible Oral Thin Films Open
In this work hydroxypropyl methylcellulose (HPMC) fast-dissolving thin films for oral administration are investigated. Furosemide (Class IV of the Biopharmaceutical Classification System) has been used as a model drug for in vitro release …
View article: Can Pulsed Electromagnetic Fields Trigger On-Demand Drug Release from High-Tm Magnetoliposomes?
Can Pulsed Electromagnetic Fields Trigger On-Demand Drug Release from High-Tm Magnetoliposomes? Open
Recently, magnetic nanoparticles (MNPs) have been used to trigger drug release from magnetoliposomes through a magneto-nanomechanical approach, where the mechanical actuation of the MNPs is used to enhance the membrane permeability. This r…
View article: Magnetoliposomes: Envisioning new strategies for water decontamination
Magnetoliposomes: Envisioning new strategies for water decontamination Open
In this work, the inclusion of magnetic nanoparticles (MNPs) within phospholipid vesicles has been investigated as novel strategy for improving stability and reactivity of these nanoparticles and extending their potential use in the enviro…