Stefanie Balk
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View article: Blood–Brain Barrier Dysfunction, Edema Formation and Functional Recovery in Ischemic and Hemorrhagic Stroke: A Retrospective Study
Blood–Brain Barrier Dysfunction, Edema Formation and Functional Recovery in Ischemic and Hemorrhagic Stroke: A Retrospective Study Open
Objectives: We aimed to determine temporal patterns of blood–brain barrier (BBB) dysfunction, edema formation and functional recovery in acute stroke. Materials and Methods: Patients of two observational studies on ischemic and hemorrhagic…
View article: Long‐Term Survival, Burden of Disease, and Patient‐Centered Outcomes in Maximally Treated Intracerebral Hemorrhage
Long‐Term Survival, Burden of Disease, and Patient‐Centered Outcomes in Maximally Treated Intracerebral Hemorrhage Open
Objective Increasing evidence shows that patients with intracerebral hemorrhage (ICH) can achieve better‐than‐expected outcomes with aggressive therapy. However, real‐world long‐term data, patient‐centered outcomes, and societal measures a…
View article: Intracerebral Hemorrhage-Associated Iron Release Leads to Pericyte-Dependent Cerebral Capillary Function Disruption
Intracerebral Hemorrhage-Associated Iron Release Leads to Pericyte-Dependent Cerebral Capillary Function Disruption Open
Intracerebral hemorrhage leads to immediate brain injury due to local mechanical damage, on which current treatment approaches are focused, but it also induces secondary brain injury. The purpose of this study is to characterize blood comp…
View article: Voices of patients’ relatives to support weaning from mechanical ventilation: a randomized trial
Voices of patients’ relatives to support weaning from mechanical ventilation: a randomized trial Open
Weaning from mechanical ventilation is complicated in patients with severe brain injury, but recurrent stimulation by familiar voices and commands to breathe in and out during critical weaning periods may improve patient outcomes. This stu…
View article: Association of non-contrast CT markers with long-term functional outcome in deep intracerebral hemorrhage
Association of non-contrast CT markers with long-term functional outcome in deep intracerebral hemorrhage Open
Objective Hematoma expansion (HE) is the most important therapeutic target during acute care of patients with intracerebral hemorrhage (ICH). Imaging biomarkers such as non-contrast CT (NCCT) markers have been associated with increasing ri…
View article: Time‐dependent risk factors for epileptic seizures in glioblastoma patients: A retrospective analysis of 520 cases
Time‐dependent risk factors for epileptic seizures in glioblastoma patients: A retrospective analysis of 520 cases Open
Objective Epilepsy is a common comorbidity of glioblastoma. Seizures may occur in various phases of the disease. We aimed to assess potential risk factors for seizures in accordance with the point in time at which they occurred. Methods We…
View article: Amantadine treatment is associated with improved consciousness in patients with non-traumatic brain injury
Amantadine treatment is associated with improved consciousness in patients with non-traumatic brain injury Open
Objective This study determined the effect of amantadine treatment on consciousness in patients with non-traumatic brain injury. Methods We pooled individual patient data of five single-centre observational studies to determine the effect …
View article: Disability-Adjusted Life-Years Associated With Intracerebral Hemorrhage and Secondary Injury
Disability-Adjusted Life-Years Associated With Intracerebral Hemorrhage and Secondary Injury Open
These findings suggest that there is a high burden of disability associated with ICH and secondary injuries, and the findings may guide public health strategies. The study findings further suggest that IVH and PHE may be relevant for the o…
View article: Impact of Statins on Hematoma, Edema, Seizures, Vascular Events, and Functional Recovery After Intracerebral Hemorrhage
Impact of Statins on Hematoma, Edema, Seizures, Vascular Events, and Functional Recovery After Intracerebral Hemorrhage Open
Background and Purpose: The impact of statins on hematoma characteristics, perihemorrhagic edema (PHE), cardiovascular events, seizures, and functional recovery in patients with intracerebral hemorrhage (ICH) is insufficiently studied. Met…