Stefanie Hermann
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Extracellular Vesicle Associated miRNAs Regulate Signaling Pathways Involved in COVID-19 Pneumonia and the Progression to Severe Acute Respiratory Corona Virus-2 Syndrome Open
Background Extracellular vesicles (EVs) are mediators of cell-to-cell communication in inflammatory lung diseases. They function as carriers for miRNAs which regulate mRNA transcripts and signaling pathways after uptake into recipient cell…
Diagnostic potential of circulating cell‐free microRNAs for community‐acquired pneumonia and pneumonia‐related sepsis Open
Cell‐free microRNAs (miRNAs) are transferred in disease state including inflammatory lung diseases and are often packed into extracellular vesicles (EVs). To assess their suitability as biomarkers for community‐acquired pneumonia (CAP) and…
Transcriptomic profiling of cell‐free and vesicular microRNAs from matched arterial and venous sera Open
Extracellular vesicles (EVs) play central physiological and pathophysiological roles in intercellular communication. Biomarker studies addressing disorders such as cardiovascular diseases often focus on circulating microRNAs (miRNAs) and m…
Human airway epithelial extracellular vesicle miRNA signature is altered upon asthma development Open
Background miRNAs are master regulators of signaling pathways critically involved in asthma and are transferred between cells in extracellular vesicles (EV). We aimed to investigate whether the miRNA content of EV secreted by primary norma…
Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by Next‐Generation Sequencing Open
[This corrects the article DOI: 10.1080/20013078.2018.1481321.].
Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next‐generation sequencing Open
Extracellular vesicles (EVs) are intercellular communicators with key functions in physiological and pathological processes and have recently garnered interest because of their diagnostic and therapeutic potential. The past decade has brou…