Stefanie Muhs
YOU?
Author Swipe
View article: Mechanism of Centrosomal Protein 55 (CEP55) Loading Into Exosomes
Mechanism of Centrosomal Protein 55 (CEP55) Loading Into Exosomes Open
Up‐regulation of Centrosomal Protein 55 (CEP55) in cancer cells increases malignancy, and the protein can be transferred via exosomes. However, the mechanism of how CEP55 is delivered to exosomes is unknown. In this study, we addressed thi…
View article: Centrosomal Protein 55 Regulates Chromosomal Instability in Cancer Cells by Controlling Microtubule Dynamics
Centrosomal Protein 55 Regulates Chromosomal Instability in Cancer Cells by Controlling Microtubule Dynamics Open
Centrosomal Protein 55 (CEP55) exhibits various oncogenic activities; it regulates the PI3K-Akt-pathway, midbody abscission, and chromosomal instability (CIN) in cancer cells. Here, we analyzed the mechanism of how CEP55 controls CIN in ov…
View article: Ex Vivo Model of Neuroblastoma Plasticity
Ex Vivo Model of Neuroblastoma Plasticity Open
Tumor plasticity is essential for adaptation to changing environmental conditions, in particular during the process of metastasis. In this study, we compared morphological and biochemical differences between LAN-1 neuroblastoma (NB) cells …
View article: Centrosomal Protein 55 increases chromosomal instability in ovarian cancer cells by controlling microtubule dynamics
Centrosomal Protein 55 increases chromosomal instability in ovarian cancer cells by controlling microtubule dynamics Open
Centrosomal Protein 55 (CEP55) exhibits different oncogenic activities; it regulates the PI3K-Akt-pathway, cellular abscission and chromosomal instability (CIN) in cancer cells. While the mechanism of CEP55-controlled PI3K-Akt signaling an…
View article: Centrosomal Protein 55 increases chromosomal instability in ovarian cancer cells by controlling microtubule dynamics
Centrosomal Protein 55 increases chromosomal instability in ovarian cancer cells by controlling microtubule dynamics Open
Background: Centrosomal Protein 55 (CEP55) exhibits different oncogenic activities; it regulates the PI3K-Akt-pathway, cellular abscission and chromosomal instability (CIN) in different types of cancer cells. While the mechanism of CEP55-c…
View article: Strong fascin expression promotes metastasis independent of its F-actin bundling activity
Strong fascin expression promotes metastasis independent of its F-actin bundling activity Open
High expression of the actin bundling protein Fascin increases the malignancy of tumor cells. Here we show that fascin expression is up-regulated in more malignant sub-cell lines of MDA-MB-231 cells as compared to parental cells. Since als…