Stefanie Trapmann
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View article: Approaches for the preparation and evaluation of hydrophilic polyethylene and polyethylene terephthalate microplastic particles suited for toxicological effect studies
Approaches for the preparation and evaluation of hydrophilic polyethylene and polyethylene terephthalate microplastic particles suited for toxicological effect studies Open
When performing effect studies to investigate the impact of microplastic (MP) on cell lines, algae, or daphnia, it is advantageous if such experiments can be performed without the use of surfactants. The need for surfactants arises from th…
Certified reference materials for GMO analysis—more than 25 years of GMO CRM production at EC JRC Open
Certified reference materials (CRMs) play a crucial role in ensuring the quality of analytical measurements. Particularly, the EU labelling legislation on genetically modified organisms (GMOs) in food and feed products explicitly requires …
Approaches for the production of reference materials with qualitative properties—The new International Standard ISO 33406 Open
The number of reference materials (RMs), including certified reference materials (CRMs) characterized for qualitative properties, has steadily increased in recent years. In response, the Technical Committee for Reference Materials of the I…
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Frontmatter Open
Plasma metanephrines and prospective prediction of tumor location, size and
Development of a certified reference material for anti-β2-glycoprotein I IgG – commutability studies Open
Objectives In this paper, we describe the steps followed for the development of a certified reference material for immunoglobulin G antibodies against β2-glycoprotein I (also known as apolipoprotein H). These steps include processing of th…
First amyloid β1‐42 certified reference material for re‐calibrating commercial immunoassays Open
Introduction Reference materials based on human cerebrospinal fluid were certified for the mass concentration of amyloid beta (Aβ)1‐42 (Aβ 42 ). They are intended to be used to calibrate diagnostic assays for Aβ 42 . Methods The three cert…
The new International Standard ISO 17034: general requirements for the competence of reference material producers Open
The International Organization for Standardization (ISO) has published ISO 17034:2016 on the minimum requirements for the competence of reference material producers. Previously these requirements were addressed in ISO Guide 34:2009, origin…
The certification of the mass concentration of immunoglobulin G proteinase 3 anti-neutrophil cytoplasmic autoantibodies (IgG PR3 ANCA) in human serum: ERM® - DA483/IFCC Open
This report describes the production and certification of ERM-DA483/IFCC, a serum protein reference material intended for the standardisation of measurements of immunoglobulin G proteinase 3 anti-neutrophil cytoplasmic autoantibodies (IgG …
Influence of primer & probe chemistry and amplification target on reverse transcription digital PCR quantification of viral RNA Open
Compared to other PCR technologies, digital PCR is a potentially highly accurate approach for the quantification of nucleic acid fragments. This study describes the impact of four experimental factors, namely primer and probe chemistry, PC…