Stefano Miceli Sopo
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View article: Food Protein-Induced Enterocolitis Syndrome Across Lifespan: Focus on Adolescence
Food Protein-Induced Enterocolitis Syndrome Across Lifespan: Focus on Adolescence Open
Background/Objectives: Food protein-induced enterocolitis syndrome (FPIES) is a food-related hypersensitivity disorder characterized by delayed repeated vomiting that typically presents within the first years of life. Although FPIES has tr…
View article: Diagnosing Paediatric Mild Acute Food Protein‐Induced Enterocolitis Syndrome: Proposal of New Criteria
Diagnosing Paediatric Mild Acute Food Protein‐Induced Enterocolitis Syndrome: Proposal of New Criteria Open
Additional data are available on public repository.
View article: Preventive therapy for childhood asthma and wheezing: Should we change our approach due to disrupted seasonality in viral circulation?
Preventive therapy for childhood asthma and wheezing: Should we change our approach due to disrupted seasonality in viral circulation? Open
To the Editor, Wheezing is common during the preschool years, with nearly 50% of children experiencing at least one episode of wheezing in the first 6 years of life.1 Recurrent wheezing in preschool children is in the vast majority of case…
View article: Is it worth already in the first step exceeding the 3‐g protein limit for the oral food challenge for food protein‐induced enterocolitis syndrome?
Is it worth already in the first step exceeding the 3‐g protein limit for the oral food challenge for food protein‐induced enterocolitis syndrome? Open
Food protein-induced enterocolitis syndrome (FPIES) is a non-immunoglobulin E-mediated food allergy that is characterized by repetitive vomiting within 1–4 h of eating the trigger food and may be associated with lethargy, pallor, and diarr…
View article: Adherence to dietary prescriptions in patients with acute food protein‐induced enterocolitis syndrome
Adherence to dietary prescriptions in patients with acute food protein‐induced enterocolitis syndrome Open
Food protein‐induced enterocolitis syndrome (FPIES) is a non‐Immunoglobulin (non‐IgE)‐mediated food allergy. The elimination diet is the only therapy, the culprit food will be reintroduced if tolerance is acquired. However, it is possible …
View article: Potential Application of Lung Ultrasound in Children with Severe Uncontrolled Asthma: Preliminary Hypothesis Based on a Case Series
Potential Application of Lung Ultrasound in Children with Severe Uncontrolled Asthma: Preliminary Hypothesis Based on a Case Series Open
In recent years, lung ultrasound (LUS) has been increasingly used for the diagnosis of respiratory diseases in both adult and pediatric patients. However, asthma is a field in which the use of LUS is not yet well defined, or is in developm…
View article: Potential Application of Lung Ultrasound in Children with Severe Uncontrolled Asthma: Preliminary Hypothesis Based on a Case Series
Potential Application of Lung Ultrasound in Children with Severe Uncontrolled Asthma: Preliminary Hypothesis Based on a Case Series Open
In recent years, lung ultrasound (LUS) has been increasingly used for the diagnosis of respiratory diseases in both adult and pediatric patients. However, asthma is a field in which the use of LUS is not yet well defined or is in developme…
View article: Non-allergic benign infantile proctocolitis: a neglected nosographic entity
Non-allergic benign infantile proctocolitis: a neglected nosographic entity Open
The presence of rectal bleeding in the first months of life is very often diagnosed as food protein-induced allergic proctocolitis (FPIAP). The symptoms typically start in infancy, and most cases resolve by age 12 months. Infants with FPIA…
View article: Functional constipation related to cow’s milk allergy in children. A management proposal
Functional constipation related to cow’s milk allergy in children. A management proposal Open
Functional constipation (FC) is one of the most common disorders in childhood and has a neg-ative impact on the quality of life of children. Scientific evidence regarding a causal relation-ship between FC and cow’s milk allergy is controve…
View article: Sensitivity of prick test with walnut commercial extracts and of prick by prick with raw walnut compared with open food challenge in walnut allergy.
Sensitivity of prick test with walnut commercial extracts and of prick by prick with raw walnut compared with open food challenge in walnut allergy. Open
In the specific case of walnut allergy in pediatric age, the execution of SPT alone with commercial extract may not be sufficient and clarifying in the diagnostic iter. We suggest to always associate the execution of PbP test.
View article: Criteria for the suspicion and diagnosis of acute food protein-induced enterocolitis syndrome
Criteria for the suspicion and diagnosis of acute food protein-induced enterocolitis syndrome Open
Over the past decades, several panels of criteria have been proposed for the diagnosis of acute food protein-induced enterocolitis syndrome (FPIES). However, none of them have been validated by a prospective study. Such a study is not easy…
View article: Oral allergy syndrome by fruit and vegetable PR-10 allergy: Accuracy of in vivo diagnosis
Oral allergy syndrome by fruit and vegetable PR-10 allergy: Accuracy of in vivo diagnosis Open
Routine diagnostic methods for allergies to plant-derived foods are based on skin prick test (SPT) with commercial extracts, prick-by-prick (PbP) with fresh food, serum-specific IgE measurement, and oral food challenge.We discuss the possi…
View article: About the recommendation of the GINA strategy report on asthma step 1
About the recommendation of the GINA strategy report on asthma step 1 Open
There is not yet sufficient evidence to transfer the use of as-needed low dose ICS–formoterol, as GINA has recommended since 2019, instead of as-needed SABA to patients affected by step 1 asthmahttps://bit.ly/2G1IieN
View article: Systemic allergic reactions induced by labile plant‐food allergens: Seeking potential cofactors. A multicenter study
Systemic allergic reactions induced by labile plant‐food allergens: Seeking potential cofactors. A multicenter study Open
Background Heat‐and‐pepsin‐sensitive plant food allergens (PR‐10 and profilin) sometimes cause systemic reaction. Objective To detect the risk factors for systemic reactions induced by labile food allergens. Methods A retrospective multice…
View article: Does delayed urticaria induced by drug allergy exist?
Does delayed urticaria induced by drug allergy exist? Open
With the help of a routine clinical case about delayed urticaria induced by drug, we have analyzed the scientific societies reports published during the last 5 years on this topic. We highlighted the differences between the EAACI consensus…
View article: Disagreement between guidelines regarding the third step of asthma drug therapy for school-age children
Disagreement between guidelines regarding the third step of asthma drug therapy for school-age children Open
With the help of a routine clinical case, we highlighted the difference between two of the best asthma guidelines available at the time regarding therapeutic suggestions for the so-called "third step" for school-age asthmatic children. We …
View article: International consensus guidelines for the diagnosis and management of food protein–induced enterocolitis syndrome: Executive summary—Workgroup Report of the Adverse Reactions to Foods Committee, American Academy of Allergy, Asthma & Immunology
International consensus guidelines for the diagnosis and management of food protein–induced enterocolitis syndrome: Executive summary—Workgroup Report of the Adverse Reactions to Foods Committee, American Academy of Allergy, Asthma & Immunology Open
Food protein-induced enterocolitis (FPIES) is a non-IgE cell- mediated food allergy that can be severe and lead to shock. Despite the potential seriousness of reactions, awareness of FPIES is low; high-quality studies providing insight int…
View article: Food Protein-Induced Enterocolitis Syndrome: Proposals for New Definitions
Food Protein-Induced Enterocolitis Syndrome: Proposals for New Definitions Open
Acute food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated allergy and is characterized by repetitive profuse vomiting episodes, often in association with pallor, lethargy, and diarrhea, presenting within 1–4 h from th…
View article: The unpredictability of seasonal variations in serum vitamin D levels in children with asthma and/or rhinitis
The unpredictability of seasonal variations in serum vitamin D levels in children with asthma and/or rhinitis Open
The wide and unpredictable variability of the individual trend of serum vitD levels should be taken into account before deciding whether or not a drug supplementation is appropriate.
View article: Yogurt is tolerated by the majority of children with IgE-mediated cow's milk allergy
Yogurt is tolerated by the majority of children with IgE-mediated cow's milk allergy Open
The results of our study are placed alongside others already present in the literature and concerning other methods of processing CM proteins and help to reduce the dietary restrictions of the majority of children with systemic IgE-CMA.
View article: Predictive value of the number of adverse reaction episodes for the IgE-mediated food allergy diagnosis
Predictive value of the number of adverse reaction episodes for the IgE-mediated food allergy diagnosis Open
The number of ARE is an important predictor of the diagnosis of food allergy, although less than we would have imagined. The number of ARE could be used to increase the predictability of the diagnostic tests currently in use, to define cli…
View article: Cooking influence in tolerance acquisition in egg-induced acute food protein enterocolitis syndrome
Cooking influence in tolerance acquisition in egg-induced acute food protein enterocolitis syndrome Open
It is possible to perform an OFC with baked egg, to verify the possible acquisition of tolerance, at about 30 months of life in children with acute egg FPIES.
View article: Is food protein induced enterocolitis syndrome only a non IgE-mediated food allergy?
Is food protein induced enterocolitis syndrome only a non IgE-mediated food allergy? Open
Food protein induced enterocolitis syndrome (FPIES) is classified as non-IgE-mediated or cell-mediated food allergy, although there is an atypical phenotype so defined for the presence of specific IgEs. All diagnostic criteria for FPIES in…
View article: Diagnostic criteria for acute food protein-induced enterocolitis syndrome. Is the work in progress?
Diagnostic criteria for acute food protein-induced enterocolitis syndrome. Is the work in progress? Open
Food protein-induced enterocolitis syndrome (FPIES) is a non IgE-mediated gastrointestinal food allergic disorder. Some diagnostic criteria have been published for acute FPIES. Of course, they are not all the same, so the clinician must ch…
View article: Loss of tolerance for fishes previously tolerated in children with fish food protein induced enterocolitis syndrome
Loss of tolerance for fishes previously tolerated in children with fish food protein induced enterocolitis syndrome Open
We describe two case reports presenting some novel information on fish FPIES. Fish FPIES to one fish does not always start at the same time to other fish. Additionally, development of tolerance to the index fish do not necessarily imply to…