Stefano Scialla
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View article: Effect of diversity distribution symmetry on global oscillations of networks of excitable units
Effect of diversity distribution symmetry on global oscillations of networks of excitable units Open
We investigate the role of the degree of symmetry of the diversity distribution in shaping the collective dynamics of networks of coupled excitable units modeled by FitzHugh-Nagumo equations. While previous studies have focused primarily o…
View article: Dynamical equivalence between resonant translocation of a polymer chain and diversity-induced resonance
Dynamical equivalence between resonant translocation of a polymer chain and diversity-induced resonance Open
Networks of heterogeneous oscillators are often seen to display collective synchronized oscillations, even when single elements of the network do not oscillate in isolation. It has been found that it is the diversity of the individual elem…
View article: Nanoscopic gel particle for intra-articular injection formulation
Nanoscopic gel particle for intra-articular injection formulation Open
Hyaluronic acid (HA) based nanogels showed effective intracellular delivery efficacy for anti-cancer and anti-inflammatory drugs, characterized by their ability targeting relevant cell receptors. In the present study, we demonstrate the ab…
View article: Learning thresholds lead to stable language coexistence
Learning thresholds lead to stable language coexistence Open
We introduce a language competition model that is based on the Abrams-Strogatz model and incorporates the effects of memory and learning in the language shift dynamics. On a coarse grained time scale, the effects of memory and learning can…
View article: A three-state language competition model including language learning and attrition
A three-state language competition model including language learning and attrition Open
We develop a three-state agent-based language competition model that takes into account the fact that language learning and attrition are not instantaneous but occur over a finite time interval; i.e., we introduce memory in the system. We …
View article: Nanogels Based on Hyaluronic Acid as Potential Active Carriers for Dermatological and Cosmetic Applications
Nanogels Based on Hyaluronic Acid as Potential Active Carriers for Dermatological and Cosmetic Applications Open
Nanogels are a prominent research topic in biomedical and drug delivery applications. The versatility of their chemistry allows them to be tailored both to carry and release a wide range of active molecules, and to target specific tissues …
View article: Diversity-induced decoherence
Diversity-induced decoherence Open
We analyze the effect of small-amplitude noise and heterogeneity in a network of coupled excitable oscillators with strong time scale separation. Using mean-field analysis, we uncover the mechanism of a new nontrivial effect -- diversity-i…
View article: Hyaluronic Acid–Polyethyleneimine Nanogels for Controlled Drug Delivery in Cancer Treatment
Hyaluronic Acid–Polyethyleneimine Nanogels for Controlled Drug Delivery in Cancer Treatment Open
The emulsion/evaporation method represents a pivotal approach to synthesize nanogels for controlled drug delivery. However, this strategy is constrained to the use of at least one polymer characterized by a phase-selective solubility in or…
View article: The interplay between diversity and noise in an excitable cell network model
The interplay between diversity and noise in an excitable cell network model Open
We study the effects of the interplay between diversity and noise in a 3D network of FitzHugh-Nagumo elements, with topology and dimensions chosen to model a pancreatic β -cell cluster, as an example of an excitable cell network. Our resul…
View article: Droplet-based microfluidic synthesis of nanogels for controlled drug delivery: tailoring nanomaterial properties <i>via</i> pneumatically actuated flow-focusing junction
Droplet-based microfluidic synthesis of nanogels for controlled drug delivery: tailoring nanomaterial properties <i>via</i> pneumatically actuated flow-focusing junction Open
A droplet-based microfluidic process relying on an actuated flow-focusing device was used for the in-flow synthesis of hyaluronic acid-polyethyleneimine nanogels with improved drug delivery properties.
View article: Hubs, diversity, and synchronization in FitzHugh-Nagumo oscillator networks: Resonance effects and biophysical implications
Hubs, diversity, and synchronization in FitzHugh-Nagumo oscillator networks: Resonance effects and biophysical implications Open
Using the FitzHugh-Nagumo equations to represent the oscillatory electrical behavior of β-cells, we develop a coupled oscillator network model with cubic lattice topology, showing that the emergence of pacemakers or hubs in the system can …