Andréas Stein
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View article: Legionella in the brain: First culture-confirmed post-surgical abscess case and its successful management
Legionella in the brain: First culture-confirmed post-surgical abscess case and its successful management Open
This case highlights the importance of molecular diagnostics and tailored therapy in managing rare brain abscesses.
View article: Crystal structure of the <i>Legionella pneumophila</i> effector SidL (Lpg0437) in complex with its metaeffector LegA11 (Lpg0436)
Crystal structure of the <i>Legionella pneumophila</i> effector SidL (Lpg0437) in complex with its metaeffector LegA11 (Lpg0436) Open
Legionella pneumophila is an opportunistic human pathogen that causes atypical pneumonia called Legionnaires’ Disease. To replicate within host cells, L. pneumophila injects up to 330 effector proteins into the host cytosol via a Dot/Icm t…
View article: First Detection of Methanogens in Orthopedic Prosthesis Infection: A Four-Case Founding Series
First Detection of Methanogens in Orthopedic Prosthesis Infection: A Four-Case Founding Series Open
Orthopedic prosthesis infection must be medically managed after appropriate microbiological documentation. While bacteria and fungi are acknowledged to be causative opportunistic pathogens in this situation, the potential role of methanoge…
View article: Evaluation of pain susceptibility by taking blood pressure in patients with infections
Evaluation of pain susceptibility by taking blood pressure in patients with infections Open
Pain sensitization leading to polyalgia can be observed during infectious diseases. The blood pressure cuff-evoked pain threshold (BPCEPT) has been used in previous studies as a screening tool for fibromyalgia. We aimed to use the BPCEPT a…
View article: Expression of ACE2, Soluble ACE2, Angiotensin I, Angiotensin II and Angiotensin-(1-7) Is Modulated in COVID-19 Patients
Expression of ACE2, Soluble ACE2, Angiotensin I, Angiotensin II and Angiotensin-(1-7) Is Modulated in COVID-19 Patients Open
The etiological agent of COVID-19 SARS-CoV-2, is primarily a pulmonary-tropic coronavirus. Infection of alveolar pneumocytes by SARS-CoV-2 requires virus binding to the angiotensin I converting enzyme 2 (ACE2) monocarboxypeptidase. ACE2, p…
View article: Expression of ACE2 receptor, soluble ACE2, Angiotensin I, Angiotensin II and Angiotensin (1-7), is modulated in COVID-19 patients
Expression of ACE2 receptor, soluble ACE2, Angiotensin I, Angiotensin II and Angiotensin (1-7), is modulated in COVID-19 patients Open
Although SARS-CoV-2 is primarily a pulmonary-tropic virus, it is nonetheless responsible for multi-organ failure in patients with severe forms of COVID-19, particularly those with hypertension or cardiovascular disease. Infection requires …
View article: Evaluating the serological status of COVID-19 patients using an indirect immunofluorescent assay, France
Evaluating the serological status of COVID-19 patients using an indirect immunofluorescent assay, France Open
An indirect immunofluorescent assay was developed in order to assess the serological status of 888 RT-PCR-confirmed COVID-19 patients (1,302 serum samples) and controls in Marseille, France. Incorporating an inactivated clinical SARS CoV-2…
View article: Metabarcoding analysis of eukaryotic microbiota in the gut of HIV-infected patients
Metabarcoding analysis of eukaryotic microbiota in the gut of HIV-infected patients Open
Research on the relationship between changes in the gut microbiota and human disease, including AIDS, is a growing field. However, studies on the eukaryotic component of the intestinal microbiota have just begun and have not yet been condu…
View article: Arthrocladium fulminans Arthritis and Osteomyelitis
Arthrocladium fulminans Arthritis and Osteomyelitis Open
Arthrocladium fulminans is the only species in the Arthrocladium genus that has been involved in a previous human infection. To date, only one case of A. fulminans infection in a patient with GATA-2 immunodeficiency has been reported. We h…