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View article: The evolution of public health statistical modeling approaches and how to advance their incorporation into modern arboviral surveillance
The evolution of public health statistical modeling approaches and how to advance their incorporation into modern arboviral surveillance Open
Statistical modeling of infectious disease transmission patterns has been in existence since the mid-1700s, evolving in their utility as the scientific and technological revolutions progressed. Despite the expansion of emerging mathematica…
View article: Assessing Simultaneous Infection with Multiple Pathogens via Group Testing with Imperfect Multiplex Assays
Assessing Simultaneous Infection with Multiple Pathogens via Group Testing with Imperfect Multiplex Assays Open
Pooled testing procedures involve physically combining biomaterial from multiple individuals and testing the combined specimen for the presence of infection. Provided the prevalence of infection is relatively low, pooled testing allows one…
View article: The conservation easement clustering patterns in U.S. urbanizing counties
The conservation easement clustering patterns in U.S. urbanizing counties Open
Conservation easement (CE) use in the U.S. and globally has expanded over the past 40 years in fringe areas adjacent to urbanization, and this article examines their spatial manifestation in twelve physically and socially heterogeneous, hi…
View article: Impact of Food Insecurity Resource Navigation for Primary Care Patients with Diabetes and Hypertension: A Matched Cohort Study
Impact of Food Insecurity Resource Navigation for Primary Care Patients with Diabetes and Hypertension: A Matched Cohort Study Open
Background Food insecurity contributes to poor health and increased healthcare costs among patients with chronic diseases. Resource navigators can facilitate community-based resource connections, addressing food insecurity, but the impact …
View article: Granular Insights:A Wastewater-Based Machine Learning Approach for Localized COVID-19 Hospitalization Forecasting
Granular Insights:A Wastewater-Based Machine Learning Approach for Localized COVID-19 Hospitalization Forecasting Open
Wastewater based epidemiology (WBE) is a valuable tool for monitoring emerging disease trends in a community. Specifically, early predictions of hospitalization in a community can help reduce the strain on healthcare services and facilitat…
View article: Variable Selection in Functional Linear Cox Model
Variable Selection in Functional Linear Cox Model Open
Modern biomedical studies frequently collect complex, high-dimensional physiological signals using wearables and sensors along with time-to-event outcomes, making efficient variable selection methods crucial for interpretation and improvin…
View article: Validating a Bayesian Spatio-Temporal Model to Predict La Crosse Virus Human Incidence in the Appalachian Mountain Region, USA
Validating a Bayesian Spatio-Temporal Model to Predict La Crosse Virus Human Incidence in the Appalachian Mountain Region, USA Open
La Crosse virus (LACV) is a rare cause of pediatric encephalitis, yet identifying and mitigating transmission foci is critical to detecting additional cases. Neurologic disease disproportionately occurs among children, and survivors often …
View article: P-1952. SARS-CoV-2 Self-Testing Modalities Demonstrate Concerning Inaccuracies Among Rural, Minority Populations: The ALL-IN SC Study
P-1952. SARS-CoV-2 Self-Testing Modalities Demonstrate Concerning Inaccuracies Among Rural, Minority Populations: The ALL-IN SC Study Open
Background At-home, diagnostic self-test assays provide a unique opportunity to reduce healthcare disparities by providing low-cost, immediate access to disease testing. Despite their utility, their real-world accuracy is unknown. Therefor…
View article: Geographic Variations in Urban‐Rural Particulate Matter (PM<sub>2.5</sub>) Concentrations in the United States, 2010–2019
Geographic Variations in Urban‐Rural Particulate Matter (PM<sub>2.5</sub>) Concentrations in the United States, 2010–2019 Open
Fine particulate matter 2.5 (PM 2.5 ) is a widely studied pollutant with substantial health impacts, yet little is known about the urban‐rural differences across the United States. Trends of PM 2.5 in urban and rural census tracts between …
View article: Employing digital PCR for enhanced detection of perinatal Toxoplasma gondii infection: A cross-sectional surveillance and maternal-infant outcomes study in El Salvador
Employing digital PCR for enhanced detection of perinatal Toxoplasma gondii infection: A cross-sectional surveillance and maternal-infant outcomes study in El Salvador Open
Toxoplasma gondii is a parasitic infection that can be transmitted in utero, resulting in fetal chorioretinitis and other long-term neurological outcomes. If diagnosed early, pregnancy-safe chemotherapeutics can prevent vertical transmissi…
View article: Unpacking conservation easements' assessed land use designations and their implications for realizing biodiversity protection
Unpacking conservation easements' assessed land use designations and their implications for realizing biodiversity protection Open
Native ecosystem and biodiversity loss from land use conversion into human‐modified landscapes are evident in the United States and globally. In addition to public land conservation, there is an increase in private land conservation throug…
View article: Antibody Seroprevalence to Spotted Fever Group Rickettsiae in Miraflores, Colombia: A Cross-Sectional Study in Humans and Dogs
Antibody Seroprevalence to Spotted Fever Group Rickettsiae in Miraflores, Colombia: A Cross-Sectional Study in Humans and Dogs Open
Tick-borne disease burdens are increasing globally, impacting mostly rural and vulnerable communities. Among the most important emerging tick-borne pathogens are the Rickettsia species within the spotted fever group (SFGR) because of their…
View article: Perinatal dengue and Zika virus cross-sectional seroprevalence and maternal-fetal outcomes among El Salvadoran women presenting for labor-and-delivery
Perinatal dengue and Zika virus cross-sectional seroprevalence and maternal-fetal outcomes among El Salvadoran women presenting for labor-and-delivery Open
Background Despite maternal flavivirus infections’ linkage to severe maternal and fetal outcomes, surveillance during pregnancy remains limited globally. Further complicating maternal screening for these potentially teratogenic pathogens i…
View article: Spotted Fever Group Rickettsia spp. Molecular and Serological Evidence among Colombian Vectors and Animal Hosts: A Historical Review
Spotted Fever Group Rickettsia spp. Molecular and Serological Evidence among Colombian Vectors and Animal Hosts: A Historical Review Open
Spotted fever group Rickettsia spp. (SFGR) are a large group of tick-borne bacteria causing important emerging and re-emerging diseases that affect animals and humans. While SFGR are found worldwide, a lack of surveillance and misdiagnosis…
View article: Eco-epidemiology of Rickettsia amblyommatis and Rickettsia parkeri in naturally infected ticks (Acari: Ixodida) from South Carolina
Eco-epidemiology of Rickettsia amblyommatis and Rickettsia parkeri in naturally infected ticks (Acari: Ixodida) from South Carolina Open
Background Spotted fever group Rickettsia (SFGR) is the largest group of Rickettsia species of clinical and veterinary importance emerging worldwide. Historically, SFGR cases were linked to Rickettsia rickettsii , the causal agent of Rocky…
View article: A nowcast model to predict outdoor flea activity in real time for the contiguous United States
A nowcast model to predict outdoor flea activity in real time for the contiguous United States Open
Background The cat flea ( Ctenocephalides felis), a parasite commonly found on both dogs and cats, is a competent vector for several zoonotic pathogens, including Dipylidium caninum (tapeworms), Bartonella henselae (responsible for cat scr…
View article: Human spotted fever group Rickettsia seroprevalence and associated epidemiologic factors among diverse, marginalized populations in South Carolina
Human spotted fever group Rickettsia seroprevalence and associated epidemiologic factors among diverse, marginalized populations in South Carolina Open
Illness caused by spotted fever group Rickettsia (SFGR) is increasing nationally, with affluent, white residents most likely to be diagnosed. The common under-representativeness of marginalized populations in research studies and these vul…
View article: Patient and Care Team Perspectives on Social Determinants of Health Screening in Primary Care
Patient and Care Team Perspectives on Social Determinants of Health Screening in Primary Care Open
Importance Health systems in the US are increasingly screening for social determinants of health (SDOH). However, guidance incorporating stakeholder feedback is limited. Objective To examine patient and care team experiences in early imple…
View article: Comparing Efficacies of Biopsy and Rapid Urease Testing for H. Pylori at a Single Institution
Comparing Efficacies of Biopsy and Rapid Urease Testing for H. Pylori at a Single Institution Open
Helicobacter pylori (H. pylori) infects > 50 % of the world’s population, leading to gastric cancer if left untreated. An estimated 26,000 gastric cancer cases will occur in the US in 2023, with 40% of cases becoming the primary cause of…
View article: The utility of a Bayesian predictive model to forecast neuroinvasive West Nile virus disease in the United States of America, 2022
The utility of a Bayesian predictive model to forecast neuroinvasive West Nile virus disease in the United States of America, 2022 Open
Arboviruses (arthropod-borne-viruses) are an emerging global health threat that are rapidly spreading as climate change, international business transport, and landscape fragmentation impact local ecologies. Since its initial detection in 1…
View article: Influence of polysubstance use on the health-related quality of life among people who inject drugs undergoing opioid agonist treatment following treatment for hepatitis C virus
Influence of polysubstance use on the health-related quality of life among people who inject drugs undergoing opioid agonist treatment following treatment for hepatitis C virus Open
For individuals with PWID, our study showed no difference in HRQOL between those who did and did not engage in PSU following HCV treatment.
View article: Emergency department use and geospatial variation in social determinants of health: a pilot study from South Carolina
Emergency department use and geospatial variation in social determinants of health: a pilot study from South Carolina Open
Background Health systems are increasingly addressing patients’ social determinants of health (SDoH)-related needs and investigating their effects on health resource use. SDoH needs vary geographically; however, little is known about how t…
View article: Chagas Disease Maternal Seroprevalence and Maternal–Fetal Health Outcomes in a Parturition Cohort in Western El Salvador
Chagas Disease Maternal Seroprevalence and Maternal–Fetal Health Outcomes in a Parturition Cohort in Western El Salvador Open
Congenital Chagas disease is a growing concern, prioritized by the World Health Organization for public health action. El Salvador is home to some of the highest Chagas disease (Trypanosoma cruzi infection) burdens in the Americas, yet pre…
View article: First report of multiple Rickettsia sp., Anaplasma sp., and Ehrlichia sp. in the San Miguel Department of El Salvador from zoonotic tick vectors
First report of multiple Rickettsia sp., Anaplasma sp., and Ehrlichia sp. in the San Miguel Department of El Salvador from zoonotic tick vectors Open
Neglected bacterial zoonoses are a group of Neglected Tropical Diseases (NTDs) that are commonly underdiagnosed and underreported due to their undifferentiated febrile illness symptomology. Spotted fever group rickettsioses (SFGR), a subse…
View article: TORCH Congenital Syndrome Infections in Central America’s Northern Triangle
TORCH Congenital Syndrome Infections in Central America’s Northern Triangle Open
TORCH pathogens are a group of globally prevalent infectious agents that may cross the placental barrier, causing severe negative sequalae in neonates, including fetal death and lifelong morbidity. TORCH infections are classically defined …