Stéphan Ehrmann
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View article: Factors associated with ICU mortality and long-term outcomes in immunocompromised patients admitted to the intensive care unit for acute respiratory failure
Factors associated with ICU mortality and long-term outcomes in immunocompromised patients admitted to the intensive care unit for acute respiratory failure Open
Background Mortality of immunocompromised patients is particularly high in intensive care units (ICUs) and mainly depends on severity at admission. Moreover, mortality is also high during the months following ICU discharge. The reasons for…
View article: PEEP-AKI-COVID ICU: Effect of positive end-expiratory pressure on acute kidney injury development in patients with COVID-19-associated acute respiratory distress syndrome: an ancillary analysis of the COVID-ICU study
PEEP-AKI-COVID ICU: Effect of positive end-expiratory pressure on acute kidney injury development in patients with COVID-19-associated acute respiratory distress syndrome: an ancillary analysis of the COVID-ICU study Open
View article: Sodium Bicarbonate for Severe Metabolic Acidemia and Acute Kidney Injury
Sodium Bicarbonate for Severe Metabolic Acidemia and Acute Kidney Injury Open
Importance The effect of sodium bicarbonate infusion on outcome in patients with severe metabolic acidemia and moderate to severe acute kidney injury is unknown. Objective To determine whether sodium bicarbonate infusion is associated with…
View article: Clinical features and prognosis of severe legionnaires’ disease requiring intensive care unit admission: a multicentric retrospective cohort study
Clinical features and prognosis of severe legionnaires’ disease requiring intensive care unit admission: a multicentric retrospective cohort study Open
In this French multicentric cohort, the LP prognosis in ICUs was apparently more favorable than in the literature, possibly because of the timely and improved LP management in ICUs.
View article: Consensus Statements on Airway Clearance Interventions in Intubated Critically Ill Patients—Protocol for a Delphi Study
Consensus Statements on Airway Clearance Interventions in Intubated Critically Ill Patients—Protocol for a Delphi Study Open
Intubated critically ill patients are susceptible to secretion accumulation because of compromised airway clearance. Various airway clearance interventions are employed to prevent complications arising from mucus retention. This Delphi stu…
View article: Characteristics and outcomes of ICU patients with sepsis transmitted by cats and dogs: the PETSEPSIS multicentre retrospective observational cohort study
Characteristics and outcomes of ICU patients with sepsis transmitted by cats and dogs: the PETSEPSIS multicentre retrospective observational cohort study Open
View article: Hurdles for the Delivery of Multinational Randomized Clinical Trials
Hurdles for the Delivery of Multinational Randomized Clinical Trials Open
Importance Ethical, administrative, regulatory, and logistical (EARL) procedures can hamper clinical trial delivery. Quantification of these hurdles is rare, prohibiting identification of areas for improvement. Objective To identify and qu…
View article: Nebulized aminoglycosides for ventilator-associated pneumonia: Methodological considerations and lessons from experimental studies
Nebulized aminoglycosides for ventilator-associated pneumonia: Methodological considerations and lessons from experimental studies Open
View article: Effect of high-flow nasal cannula oxygen versus standard oxygen on mortality in patients with acute hypoxaemic respiratory failure: protocol for a multicentre, randomised controlled trial (SOHO)
Effect of high-flow nasal cannula oxygen versus standard oxygen on mortality in patients with acute hypoxaemic respiratory failure: protocol for a multicentre, randomised controlled trial (SOHO) Open
Introduction First-line oxygenation strategy in patients with acute hypoxaemic respiratory failure consists in standard oxygen or high-flow nasal oxygen therapy. Clinical practice guidelines suggest the use of high-flow nasal oxygen rather…
View article: Pressure control plus spontaneous ventilation versus volume assist-control ventilation in acute respiratory distress syndrome. A randomised clinical trial
Pressure control plus spontaneous ventilation versus volume assist-control ventilation in acute respiratory distress syndrome. A randomised clinical trial Open
View article: Transcranial doppler ultrasound for the diagnosis of large vessel occlusion in patients with acute ischemic stroke: A systematic review
Transcranial doppler ultrasound for the diagnosis of large vessel occlusion in patients with acute ischemic stroke: A systematic review Open
TCD is as a promising non-invasive and cost-effective tool for LVO diagnosis, presenting opportunities to enhance stroke management.
View article: Post-intensive care syndrome screening: a French multicentre survey
Post-intensive care syndrome screening: a French multicentre survey Open
View article: Impact of intensive prone position therapy on outcomes in intubated patients with ARDS related to COVID-19
Impact of intensive prone position therapy on outcomes in intubated patients with ARDS related to COVID-19 Open
View article: Inadequate intensive care physician supply in France: a point-prevalence prospective study
Inadequate intensive care physician supply in France: a point-prevalence prospective study Open
Background The COVID-19 pandemic has highlighted the importance of intensive care units (ICUs) and their organization in healthcare systems. However, ICU capacity and availability are ongoing concerns beyond the pandemic, particularly due …
View article: Correction: Management of hematological patients requiring emergency chemotherapy in the intensive care unit
Correction: Management of hematological patients requiring emergency chemotherapy in the intensive care unit Open
View article: Management of hematological patients requiring emergency chemotherapy in the intensive care unit
Management of hematological patients requiring emergency chemotherapy in the intensive care unit Open
View article: Pressure versus volume assist-control ventilation in Acute Respiratory Distress Syndrome: a randomised clinical trial.
Pressure versus volume assist-control ventilation in Acute Respiratory Distress Syndrome: a randomised clinical trial. Open
Background: To compare the effect of a pressure-controlled strategy allowing non-synchronized unassisted spontaneous ventilation (PC-SV) to a conventional volume assist-control strategy (ACV) on the outcome of patients with Acute Respirato…
View article: Ventilator-associated pneumonia related to extended-spectrum beta-lactamase producing Enterobacterales during severe acute respiratory syndrome coronavirus 2 infection: risk factors and prognosis
Ventilator-associated pneumonia related to extended-spectrum beta-lactamase producing Enterobacterales during severe acute respiratory syndrome coronavirus 2 infection: risk factors and prognosis Open
View article: Care of the critically ill begins in the emergency medicine setting
Care of the critically ill begins in the emergency medicine setting Open
International audience
View article: Correction: Clinical spectrum and prognostic impact of cancer in critically ill patients with HIV: a multicentre cohort study
Correction: Clinical spectrum and prognostic impact of cancer in critically ill patients with HIV: a multicentre cohort study Open
View article: Impact of daily cyclic enteral nutrition versus standard continuous enteral nutrition in critically ill patients: a study protocol for a randomised controlled trial in three intensive care units in France (DC-SCENIC)
Impact of daily cyclic enteral nutrition versus standard continuous enteral nutrition in critically ill patients: a study protocol for a randomised controlled trial in three intensive care units in France (DC-SCENIC) Open
Introduction Current guidelines on clinical nutrition of ventilated patients in the intensive care unit (ICU) recommend initiating continuous enteral nutrition within 48 hours of ICU admission when feasible. However, discontinuous feeding …
View article: Prevention of ventilator-associated pneumonia with inhaled antibiotics
Prevention of ventilator-associated pneumonia with inhaled antibiotics Open
View article: Sex difference in the risk of extubation failure in ICUs
Sex difference in the risk of extubation failure in ICUs Open
View article: Inhaled drug delivery: a randomized study in intubated patients with healthy lungs
Inhaled drug delivery: a randomized study in intubated patients with healthy lungs Open
View article: Influence of mesh nebulizer characteristics on aerosol delivery in non-human primates
Influence of mesh nebulizer characteristics on aerosol delivery in non-human primates Open
Non-Human Primates (NHPs) are particularly relevant for preclinical studies during the development of inhaled biologics. However, aerosol inhalation in NHPs is difficult to evaluate due to a low lung deposition fraction and high variabilit…
View article: Prophylactic platelet transfusion response in critically ill patients: a prospective multicentre observational study
Prophylactic platelet transfusion response in critically ill patients: a prospective multicentre observational study Open
Background Response to prophylactic platelet transfusion is suspected to be inconsistent in critically ill patients questioning how to optimize transfusion practices. This study aimed to describe prophylactic platelet transfusion response,…
View article: Awake prone positioning in acute hypoxaemic respiratory failure: An international expert guidance
Awake prone positioning in acute hypoxaemic respiratory failure: An international expert guidance Open
View article: Clinical spectrum and prognostic impact of cancer in critically ill patients with HIV: a multicentre cohort study
Clinical spectrum and prognostic impact of cancer in critically ill patients with HIV: a multicentre cohort study Open
View article: Aerosol therapy in adult critically ill patients: a consensus statement regarding aerosol administration strategies during various modes of respiratory support
Aerosol therapy in adult critically ill patients: a consensus statement regarding aerosol administration strategies during various modes of respiratory support Open
View article: Respiratory challenges and ventilatory management in different types of acute brain-injured patients
Respiratory challenges and ventilatory management in different types of acute brain-injured patients Open