Stéphan Grimaldi
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View article: Functional movement and gait disorders: A matter of age?
Functional movement and gait disorders: A matter of age? Open
FND age of onset was significantly associated with phenotype, with older patients being more affected by FGD. This association may be partially influenced by societal perceptions of aging and mobility.
View article: Prodromal Parkinson's disease
Prodromal Parkinson's disease Open
The neurodegenerative process responsible for Parkinson's disease (PD) begins years before the level of dopamine denervation of the basal ganglia leads to the characteristic clinical phenotype of the disease. During the past 20years, numer…
View article: Validation of the French Translation of the Movement Disorder Society Non‐Motor Symptoms Scale (<scp>MDS</scp>‐<scp>NMS</scp>) in Parkinson's Disease
Validation of the French Translation of the Movement Disorder Society Non‐Motor Symptoms Scale (<span>MDS</span>‐<span>NMS</span>) in Parkinson's Disease Open
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View article: 18F-FDG brain PET: a metabolic predictive factor for gait improvement after cerebrospinal fluid shunting in normal pressure hydrocephalus?
18F-FDG brain PET: a metabolic predictive factor for gait improvement after cerebrospinal fluid shunting in normal pressure hydrocephalus? Open
This preliminary study using brain 18F-FDG PET suggests that reduced brain metabolism in the thalamus and striatum along with cortical hypometabolism may be associated with poorer gait response to CSF shunting in normal pressure hydrocepha…
View article: Face of the Giant Panda Sign in Older Adults: Consider Lymphoma
Face of the Giant Panda Sign in Older Adults: Consider Lymphoma Open
A 72-year-old man with rapidly progressive gait disturbances and behavioral changes was referred to our Movement Disorders unit. His brain magnetic resonance images (Fig. 1) showed the face of the giant panda sign, which is considered char…
View article: Molecular Imaging in <scp>CANVAS</scp>: A Contribution for Differential Diagnosis?
Molecular Imaging in <span>CANVAS</span>: A Contribution for Differential Diagnosis? Open
Background Phenotypes of CANVAS are increasingly diversified, including bradykinesia and dysautonomia, so that its primary differential diagnoses are multiple system atrophy‐cerebellar type (MSA‐c), and spinocerebellar ataxia type 3 (SCA3)…
View article: Brain MRI Biomarkers in Isolated Rapid Eye Movement Sleep Behavior Disorder: Where Are We? A Systematic Review
Brain MRI Biomarkers in Isolated Rapid Eye Movement Sleep Behavior Disorder: Where Are We? A Systematic Review Open
The increasing number of MRI studies focused on prodromal Parkinson’s Disease (PD) demonstrates a strong interest in identifying early biomarkers capable of monitoring neurodegeneration. In this systematic review, we present the latest inf…
View article: Increased Sodium Concentration in Substantia Nigra in Early Parkinson's Disease: A Preliminary Study With Ultra-High Field (7T) MRI
Increased Sodium Concentration in Substantia Nigra in Early Parkinson's Disease: A Preliminary Study With Ultra-High Field (7T) MRI Open
Pathophysiology of idiopathic Parkinson's disease (iPD) is complex and still misunderstood. At a time when treatments with disease-modifying potential are being developed, identification of early markers of neurodegeneration is essential. …
View article: Single Photon Emission Computed Tomography/Positron Emission Tomography Molecular Imaging for Parkinsonism: A Fast‐Developing Field
Single Photon Emission Computed Tomography/Positron Emission Tomography Molecular Imaging for Parkinsonism: A Fast‐Developing Field Open
The early differential diagnosis of Parkinson disease and atypical parkinsonism is a major challenge. The use of single photon emission computed tomography (SPECT)/positron emission tomography (PET) molecular imaging to investigate parkins…
View article: Decrease in the Cortex/striatum Metabolic Ratio on 18F-FDG PET: a Biomarker of Dysimmune Encephalitis
Decrease in the Cortex/striatum Metabolic Ratio on 18F-FDG PET: a Biomarker of Dysimmune Encephalitis Open
Purpose: The aim was to determine the diagnostic value of the cortex/striatum metabolic ratio in 18F-FDG PET in a large cohort of patients suffering from dysimmune encephalitis (DE) and to search for clinical correlations with the course o…
View article: Autoimmune Encephalitis Concomitant with SARS-CoV-2 Infection: Insight from <sup>18</sup>F-FDG PET Imaging and Neuronal Autoantibodies
Autoimmune Encephalitis Concomitant with SARS-CoV-2 Infection: Insight from <sup>18</sup>F-FDG PET Imaging and Neuronal Autoantibodies Open
We report the case of a 72-y-old man with concomitant autoimmune encephalitis and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The patient presented with subacute cerebellar syndrome and myoclonus several days af…
View article: Association of Posterior Reversible Encephalopathy Syndrome and Transient Apical Ballooning Syndrome (Takotsubo): First Case Report of a Man and Review of the Literature
Association of Posterior Reversible Encephalopathy Syndrome and Transient Apical Ballooning Syndrome (Takotsubo): First Case Report of a Man and Review of the Literature Open
Introduction: An association of posterior reversible encephalopathy syndrome (PRES) and takotsubo is rare. We present the first case of a male patient. Case Report: A 69-year-old man presented to the hospital in a persistent comatose state…