Stephan Irsen
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Species–specific circuitry of double cone photoreceptors in two avian retinas Open
In most avian retinas, double cones (consisting of a principal and accessory member) outnumber other photoreceptor types and have been associated with various functions, such as encoding luminance, sensing polarized light, and magnetorecep…
Strong coupling between WS<sub>2</sub> monolayer excitons and a hybrid plasmon polariton at room temperature Open
Light–matter interactions between plasmonic and excitonic modes have attracted considerable interest in recent years. A major challenge in achieving strong coupling is the identification of suitable metallic nanostructures that combine tig…
Strong coupling between WS$_2$ monolayer excitons and a hybrid plasmon polariton at room temperature Open
Light-matter interactions in solid-state systems have attracted considerable interest in recent years. Here, we report on a room-temperature study on the interaction of tungsten disulfide (WS$_2$) monolayer excitons with a hybrid plasmon p…
Double Cones and the Diverse Connectivity of Photoreceptors and Bipolar Cells in an Avian Retina Open
Double cones are the most common photoreceptor cell type in most avian retinas, but their precise functions remain a mystery. Among their suggested functions are luminance detection, polarized light detection, and light-dependent, radical …
Electron energy loss spectroscopy on freestanding perforated gold films Open
We report on a combined far- and near-field study of surface plasmon\npolaritons on freestanding perforated gold films. The samples are fabricated by\nfocused ion beam milling of {a periodic hole array into} a carbon membrane\nfollowed by …
View article: FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments
FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments Open
Tau aggregation into amyloid fibers based on the cross-beta structure is a hallmark of several Tauopathies, including Alzheimer Disease (AD). Trans-cellular propagation of Tau with pathological conformation has been suggested as a key dise…
Interferometric near-field characterization of plasmonic slot waveguides in single- and poly-crystalline gold films Open
Single-crystalline gold films show superior plasmonic properties compared to their poly-crystalline counterparts. However, this advantage comes at the cost of a more complex preparation process. It is thus crucial to validate whether the i…
View article: FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments
FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments Open
Tau aggregation into amyloid fibers based on the cross-beta structure is a hallmark of several Tauopathies, including Alzheimer Disease (AD). Trans-cellular propagation of Tau with pathological conformation has been suggested as a key dise…
View article: FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau fibers
FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau fibers Open
Tau aggregation into amyloid fibers based on the cross-beta structure is a hallmark of several Tauopathies, including Alzheimer Disease (AD). Trans-cellular propagation of Tau with pathological conformation has been suggested as a key dise…
Extracellular Vesicle Isolation and Characterization from Periprosthetic Joint Synovial Fluid in Revision Total Joint Arthroplasty Open
Extracellular vesicles (EVs) comprise an as yet insufficiently investigated intercellular communication pathway in the field of revision total joint arthroplasty (RTJA). This study examined whether periprosthetic joint synovial fluid conta…
Retinal horizontal cells use different synaptic sites for global feedforward and local feedback signaling Open
In the outer plexiform layer (OPL) of the mouse retina, two types of cone photoreceptors (cones) provide input to more than a dozen types of cone bipolar cells (CBCs). This transmission is modulated by a single horizontal cell (HC) type, t…
Crossing borders of material science – a new approach of aerogel preparation for electron microscopy Open
A new method for the embedding and preparation of organic aerogels for electron mciroscopic Analysis like Crosssectioning, Lamella preparation, FIB-Tomography and Transmissio Electron Microscopy
Freestanding metasurfaces for optical frequencies Open
We present freestanding metasurfaces operating at optical frequencies with a total thickness of only 40 nm. The metasurfaces are fabricated by focused ion beam milling of nanovoids in a carbon film followed by thermal evaporation of gold a…
Near-field study on the transition from localized to propagating plasmons on 2D nano-triangles Open
In this manuscript we report on a near field study of two-dimensional plasmonic gold nano-triangles using electron energy loss spectroscopy in combination with scanning transmission electron microscopy, as well as discontinuous Galerkin ti…
Additional file 5: Figure S5. of The release and trans-synaptic transmission of Tau via exosomes Open
Uptake and transmission of TauCFP by neurons cultured in microfluidic chambers via exosomes derived from cultured neurons. (A) Nanoparticle tracking analysis of exosomes derived from primary neurons transfected with TauCFP. The size distri…