Stephan Korn
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View article: Rising metastatic prostate cancer rates but narrowing racial gap
Rising metastatic prostate cancer rates but narrowing racial gap Open
The racial gap in metastatic PCa narrowed over the study period, while overall incidence increased. Higher screening rates among Black men in the early 2010s may explain the narrowing gap. The subsequent more rapid decline among Black men …
View article: Association of Travel Burden with Definitive Prostate Cancer Treatment: A United States Registry Cohort Study
Association of Travel Burden with Definitive Prostate Cancer Treatment: A United States Registry Cohort Study Open
Purpose Prostate cancer (PCa) mortality disparities are partly driven by unequal access to care. Transportation barriers may limit access to definitive treatment. We studied how driving travel time affects receipt of definitive PCa treatme…
View article: Disparities in tissue-based biomarker testing among US Medicare beneficiaries with prostate cancer
Disparities in tissue-based biomarker testing among US Medicare beneficiaries with prostate cancer Open
Background Personalized therapeutic approaches for localized prostate cancer have evolved significantly, with tissue-based biomarker tests supplementing traditional risk stratification tools. However, national testing patterns and geograph…
View article: Impact of immigration background on feasibility of electronic patient-reported outcomes in advanced urothelial cancer patients
Impact of immigration background on feasibility of electronic patient-reported outcomes in advanced urothelial cancer patients Open
In this study, ePROs were a feasible method to assess symptoms and QoL during the systemic cancer therapy of UC patients at our center. The compliance of patients with immigration backgrounds was the most significant barrier to using ePROs…
View article: The silent struggle: anxiety in men with prostate cancer
The silent struggle: anxiety in men with prostate cancer Open
View article: Rescue From Permanent Kidney Injury in Acute Thrombosis of Both Renal Veins, the Inferior Vena Cava, and Both Iliofemoral Veins by Catheter-Based Thrombectomy
Rescue From Permanent Kidney Injury in Acute Thrombosis of Both Renal Veins, the Inferior Vena Cava, and Both Iliofemoral Veins by Catheter-Based Thrombectomy Open
Case: A 33-year-old man with previously diagnosed lupus membranous nephropathy presented with painful swelling in both legs. Laboratory tests revealed acute kidney injury, and imaging studies by duplex ultrasound and computed tomography sc…
View article: Clinical parameters for the prediction of occult lymph node metastasis in patients with negative PSMA-PET
Clinical parameters for the prediction of occult lymph node metastasis in patients with negative PSMA-PET Open
The currently used nomogram is suboptimal in detecting patients with occult LNM. While the cut-off value to perform ePLND can be increased slightly following a negative PSMA-PET scan, more accurate methods of identifying these patients are…
View article: Evidence and emerging trends in local therapy for metastatic hormone-sensitive prostate cancer: a narrative review
Evidence and emerging trends in local therapy for metastatic hormone-sensitive prostate cancer: a narrative review Open
View article: Treatment Patterns and Real-World Outcomes for Locally Advanced or Metastatic Urothelial Cancer in the Era of Immunotherapy
Treatment Patterns and Real-World Outcomes for Locally Advanced or Metastatic Urothelial Cancer in the Era of Immunotherapy Open
We looked at the lines of therapy and outcomes for patients with advanced or metastatic cancer of the urinary tract, starting from when immunotherapy drugs called immune checkpoint inhibitors (ICIs) became available. We found that 60% of p…
View article: Focal therapy in intermediate- and high-risk prostate cancer
Focal therapy in intermediate- and high-risk prostate cancer Open
Summary Focal therapy is a treatment option for clinically localized prostate cancer, finding increased use in recent years. It is generally associated with very good functional outcome regarding pad-free continence and preservation of ere…
View article: Imaging and therapy targeting PSMA receptors for enhanced vision and precise treatment
Imaging and therapy targeting PSMA receptors for enhanced vision and precise treatment Open
Summary In Europe, it is estimated that more than 65,000 men die each year from the consequences of advanced and metastatic prostate cancer (PCa). Currently, approximately 3.2 million European men are living with PCa. While the majority of…
View article: Positive family history as a predictor for disease outcomes after radical prostatectomy for nonmetastatic prostate cancer
Positive family history as a predictor for disease outcomes after radical prostatectomy for nonmetastatic prostate cancer Open
We found that patients with clinically nonmetastatic PCa who have positive FHx of PCa undergo RP at a younger age and have more favorable pathologic outcomes. Nevertheless, FHx of PCa did not confer better BCR rates, suggesting that FHx le…
View article: Evaluation of APOBEC3 expression as prognostic marker in squamous cell carcinoma of the penis
Evaluation of APOBEC3 expression as prognostic marker in squamous cell carcinoma of the penis Open
View article: Impact of PI-QUAL on PI-RADS and cancer yield in an MRI-TRUS fusion biopsy population
Impact of PI-QUAL on PI-RADS and cancer yield in an MRI-TRUS fusion biopsy population Open
PI-QUAL has only a limited impact on PI-RADS diagnostic performance in patients scheduled for MRI-TRUS fusion biopsy. However, the lower cancer prevalence in the lower PI-QUAL categories points out a risk of false-positive referrals and un…
View article: Rectal preparation significantly improves prostate imaging quality: Assessment of the PI-QUAL score with visual grading characteristics
Rectal preparation significantly improves prostate imaging quality: Assessment of the PI-QUAL score with visual grading characteristics Open
Rectal preparation significantly improved prostate imaging quality (PI-QUAL) and lesion visibility. Hence, a rectal preparation regimen consisting of a rectal cleansing enema and an endorectal gel filling could be considered.
View article: Evaluation of the Predictive Role of Blood-Based Biomarkers in the Context of Suspicious Prostate MRI in Patients Undergoing Prostate Biopsy
Evaluation of the Predictive Role of Blood-Based Biomarkers in the Context of Suspicious Prostate MRI in Patients Undergoing Prostate Biopsy Open
The aim of this study was to assess the predictive value of pre-biopsy blood-based markers in patients undergoing a fusion biopsy for suspicious prostate magnetic resonance imaging (MRI). We identified 365 consecutive patients who underwen…
View article: Expression Analysis and Mutational Status of Histone Methyltransferase KMT2D at Different Upper Tract Urothelial Carcinoma Locations
Expression Analysis and Mutational Status of Histone Methyltransferase KMT2D at Different Upper Tract Urothelial Carcinoma Locations Open
The gene coding for histone methyltransferase KMT2D is found among the top mutated genes in upper tract urothelial carcinoma (UTUC); however, there is a lack of data regarding its association with clinicopathologic features as well as surv…
View article: Visibility of significant prostate cancer on multiparametric magnetic resonance imaging (MRI)—do we still need contrast media?
Visibility of significant prostate cancer on multiparametric magnetic resonance imaging (MRI)—do we still need contrast media? Open
View article: Diagnostic accuracy, clinical utility and influence on decision‐making of a methylation urine biomarker test in the surveillance of non‐muscle‐invasive bladder cancer
Diagnostic accuracy, clinical utility and influence on decision‐making of a methylation urine biomarker test in the surveillance of non‐muscle‐invasive bladder cancer Open
Objectives To investigate prospectively the clinical utility and influence on decision‐making of Bladder EpiCheck™, a non‐invasive urine test, in the surveillance of non‐muscle‐invasive bladder cancer ( NMIBC ). Materials and Methods Urine…
View article: 68Ga-PSMA 11 ligand PET imaging in patients with biochemical recurrence after radical prostatectomy – diagnostic performance and impact on therapeutic decision-making
68Ga-PSMA 11 ligand PET imaging in patients with biochemical recurrence after radical prostatectomy – diagnostic performance and impact on therapeutic decision-making Open
View article: Impact of the Level of Urothelial Carcinoma Involvement of the Prostate on Survival after Radical Cystectomy
Impact of the Level of Urothelial Carcinoma Involvement of the Prostate on Survival after Radical Cystectomy Open
Objective: Urothelial prostatic involvement (UPI) at the time of radical cystoprostatectomy (RCP) was found associated with worse survival outcomes by several previous reports. Our aim is to evaluate the impact of different levels of UPI o…
View article: How to optimally manage elderly bladder cancer patients?
How to optimally manage elderly bladder cancer patients? Open
Bladder cancer (BCa) is a disease of the elderly and as the population is aging, BCa will become an even bigger public health challenge in the future. Nowadays the correct management of BCa in the elderly remains controversial. The purpose…