Stéphane Doly
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View article: 5‐ <scp>HT</scp> <sub>6</sub> Receptor Inverse Agonists Modulate Diabetic Neuropathic Pain in Female Rats: Evidence for 5‐ <scp>HT</scp> <sub>6</sub> Receptor Constitutive Activity
5‐ <span>HT</span> <sub>6</sub> Receptor Inverse Agonists Modulate Diabetic Neuropathic Pain in Female Rats: Evidence for 5‐ <span>HT</span> <sub>6</sub> Receptor Constitutive Activity Open
Painful neuropathy is one of the most common complications of diabetes. First‐line therapeutic agents such as tricyclic antidepressants, dual serotonin/noradrenaline reuptake inhibitors, and alpha2‐delta ligands of calcium channels (i.e., …
View article: Diabetic Neuropathic Pain and Serotonin: What Is New in the Last 15 Years?
Diabetic Neuropathic Pain and Serotonin: What Is New in the Last 15 Years? Open
The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) is involved in numerous physiological functions and plays a key role in pain modulation including neuropathic pain. Diabetic neuropathy is a common complication of diabetes mellitu…
View article: The Constitutive Activity of Spinal 5-HT6 Receptors Contributes to Diabetic Neuropathic Pain in Rats
The Constitutive Activity of Spinal 5-HT6 Receptors Contributes to Diabetic Neuropathic Pain in Rats Open
Diabetic neuropathy is often associated with chronic pain. Serotonin type 6 (5-HT6) receptor ligands, particularly inverse agonists, have strong analgesic potential and may be new candidates for treating diabetic neuropathic pain and assoc…
View article: Pharmacological chaperone-rescued cystic fibrosis CFTR-F508del mutant overcomes PRAF2-gated access to endoplasmic reticulum exit sites
Pharmacological chaperone-rescued cystic fibrosis CFTR-F508del mutant overcomes PRAF2-gated access to endoplasmic reticulum exit sites Open
View article: Récepteur 5-HT<sub>6</sub>et mTOR
Récepteur 5-HT<sub>6</sub>et mTOR Open
View article: Récepteur 5-HT6 et mTOR
Récepteur 5-HT6 et mTOR Open
View article: mTOR activation by constitutively active serotonin6 receptors as new paradigm in neuropathic pain and its treatment
mTOR activation by constitutively active serotonin6 receptors as new paradigm in neuropathic pain and its treatment Open
View article: Mechanical GPCR Activation by Traction Forces Exerted on Receptor <i>N</i>-Glycans
Mechanical GPCR Activation by Traction Forces Exerted on Receptor <i>N</i>-Glycans Open
Cells are sensitive to chemical stimulation which is converted into intracellular biochemical signals by the activation of specific receptors. Mechanical stimulations can also induce biochemical responses via the activation of various mech…
View article: Sialic acid mediated mechanical activation of β2 adrenergic receptors by bacterial pili
Sialic acid mediated mechanical activation of β2 adrenergic receptors by bacterial pili Open
Meningococcus utilizes β-arrestin selective activation of endothelial cell β 2 adrenergic receptor (β 2 AR) to cause meningitis in humans. Molecular mechanisms of receptor activation by the pathogen and of its species selectivity remained …
View article: Positive regulation of raphe serotonin neurons by serotonin 2B receptors
Positive regulation of raphe serotonin neurons by serotonin 2B receptors Open
View article: Adaptive Control of Dorsal Raphe by 5-HT4 in the Prefrontal Cortex Prevents Persistent Hypophagia following Stress
Adaptive Control of Dorsal Raphe by 5-HT4 in the Prefrontal Cortex Prevents Persistent Hypophagia following Stress Open
View article: Serotonin 2B receptors in mesoaccumbens dopamine pathway regulate cocaine responses
Serotonin 2B receptors in mesoaccumbens dopamine pathway regulate cocaine responses Open
Addiction is a maladaptive pattern of behavior following repeated use of reinforcing drugs in predisposed individuals, leading to lifelong changes. Common among these changes are alterations of neurons releasing dopamine in the ventral and…
View article: Serotonin 2B Receptors in Mesoaccumbens Dopamine Pathway Regulate Cocaine Responses
Serotonin 2B Receptors in Mesoaccumbens Dopamine Pathway Regulate Cocaine Responses Open
Addiction is a maladaptive pattern of behavior following repeated use of reinforcing drugs in predisposed individuals, leading to lifelong changes. Common among these changes are alterations of neurons releasing dopamine in the ventral and…
View article: Heterodimers of serotonin receptor subtypes 2 are driven by 5-HT2C protomers
Heterodimers of serotonin receptor subtypes 2 are driven by 5-HT2C protomers Open
View article: Mice lacking the serotonin 5-HT 2B receptor as an animal model of resistance to selective serotonin reuptake inhibitors antidepressants
Mice lacking the serotonin 5-HT 2B receptor as an animal model of resistance to selective serotonin reuptake inhibitors antidepressants Open
View article: Anatomical and ultrastructural study of PRAF2 expression in the mouse central nervous system
Anatomical and ultrastructural study of PRAF2 expression in the mouse central nervous system Open
View article: Gatekeepers Controlling GPCR Export and Function
Gatekeepers Controlling GPCR Export and Function Open
View article: Trafic cellulaire des récepteurs GABA<sub>B</sub>vers la membrane : PRAF2, un nouveau point de contrôle
Trafic cellulaire des récepteurs GABA<sub>B</sub>vers la membrane : PRAF2, un nouveau point de contrôle Open
View article: Commentary: Chronic SSRI stimulation of astrocytic 5-HT2B receptors change multiple gene expressions/editings and metabolism of glutamate, glucose and glycogen: a potential paradigm shift
Commentary: Chronic SSRI stimulation of astrocytic 5-HT2B receptors change multiple gene expressions/editings and metabolism of glutamate, glucose and glycogen: a potential paradigm shift Open
GENERAL COMMENTARY article Front. Behav. Neurosci., 05 August 2015Sec. Pathological Conditions Volume 9 - 2015 | https://doi.org/10.3389/fnbeh.2015.00207
View article: GABAB receptor cell-surface export is controlled by an endoplasmic reticulum gatekeeper
GABAB receptor cell-surface export is controlled by an endoplasmic reticulum gatekeeper Open
View article: Commentary: Chronic SSRI stimulation of astrocytic 5-HT2B receptors change multiple gene expressions/editings and metabolism of glutamate, glucose and glycogen: a potential paradigm shift
Commentary: Chronic SSRI stimulation of astrocytic 5-HT2B receptors change multiple gene expressions/editings and metabolism of glutamate, glucose and glycogen: a potential paradigm shift Open
Working on the serotonin (5-hydroxytryptamine, 5-HT) 5-HT2B receptor since several years, we have read with high interest the review by Hertz et al. (2015). Previous studies from our group demonstrated that a direct injection in mouse raph…