Stephanie Chen
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View article: 503 Multi-omics analysis of the ZUMA-7 study reveals 7 types of tumor microenvironments in large B-cell lymphoma featuring mechanisms of resistance to CAR T cell therapy & strategies for improving outcome
503 Multi-omics analysis of the ZUMA-7 study reveals 7 types of tumor microenvironments in large B-cell lymphoma featuring mechanisms of resistance to CAR T cell therapy & strategies for improving outcome Open
View article: Healthcare Resource Utilisation and Costs in Patients with Eosinophilic Granulomatosis with Polyangiitis: A Retrospective Analysis of German Insurance Claims Data
Healthcare Resource Utilisation and Costs in Patients with Eosinophilic Granulomatosis with Polyangiitis: A Retrospective Analysis of German Insurance Claims Data Open
These real-world data highlight the substantial economic burden associated with EGPA, characterised by increased HCRU, costs and productivity losses, underscoring the need for effective management strategies.
View article: Systematic Literature Review of Real-World Outcomes of Benralizumab in Eosinophilic Granulomatosis With Polyangiitis
Systematic Literature Review of Real-World Outcomes of Benralizumab in Eosinophilic Granulomatosis With Polyangiitis Open
In real-world reports, benralizumab was associated with significant oral corticosteroid-sparing effects and clinical remission in a significant proportion of patients with eosinophilic granulomatosis with polyangiitis.
View article: Microsurgical Treatment of Intracranial Dural Arteriovenous Fistulas: A Collaborative Investigation From the Multicenter Consortium for Dural Arteriovenous Fistula Outcomes Research
Microsurgical Treatment of Intracranial Dural Arteriovenous Fistulas: A Collaborative Investigation From the Multicenter Consortium for Dural Arteriovenous Fistula Outcomes Research Open
BACKGROUND AND OBJECTIVES: First-line therapy for most intracranial dural arteriovenous fistulas (dAVFs) is endovascular embolization, but some require microsurgical ligation due to limited endovascular accessibility, anticipated lower cur…
View article: Feasibility of Using a Wearable Camera, the Automatic Ingestion Monitor-2 (AIM-2), for Dietary Intake Assessment in Patients with Chronic Kidney Disease
Feasibility of Using a Wearable Camera, the Automatic Ingestion Monitor-2 (AIM-2), for Dietary Intake Assessment in Patients with Chronic Kidney Disease Open
View article: Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions
Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions Open
View article: Childhood opportunity and appropriate use of child safety restraints in motor vehicle collisions
Childhood opportunity and appropriate use of child safety restraints in motor vehicle collisions Open
Objectives Safety restraints reduce injuries from motor vehicle collisions (MVCs) but are often improperly applied or not used. The Childhood Opportunity Index (COI) reflects social determinants of health and its study in pediatric trauma …
View article: Management of undifferentiated embryonal sarcoma of the liver: A Pediatric Surgical Oncology Research Collaborative study
Management of undifferentiated embryonal sarcoma of the liver: A Pediatric Surgical Oncology Research Collaborative study Open
Background Undifferentiated embryonal sarcoma of the liver (UESL) is a rare tumor for which there are few evidence‐based guidelines. The aim of this study was to define current management strategies and outcomes for these patients using a …
View article: The therapeutically actionable long non-coding RNA ‘T-RECS’ is essential to cancer cells’ survival in NRAS/MAPK-driven melanoma
The therapeutically actionable long non-coding RNA ‘T-RECS’ is essential to cancer cells’ survival in NRAS/MAPK-driven melanoma Open
Finding effective therapeutic targets to treat NRAS-mutated melanoma remains a challenge. Long non-coding RNAs (lncRNAs) recently emerged as essential regulators of tumorigenesis. Using a discovery approach combining experimental models an…
View article: Healthcare resource utilization and costs in patients with eosinophilic granulomatosis with polyangiitis versus severe uncontrolled asthma: a retrospective analysis of US health insurance claims data
Healthcare resource utilization and costs in patients with eosinophilic granulomatosis with polyangiitis versus severe uncontrolled asthma: a retrospective analysis of US health insurance claims data Open
View article: Comorbidities in patients with eosinophilic granulomatosis with polyangiitis and severe uncontrolled asthma: a retrospective analysis of US health insurance claims data
Comorbidities in patients with eosinophilic granulomatosis with polyangiitis and severe uncontrolled asthma: a retrospective analysis of US health insurance claims data Open
View article: The impact of COVID-19 on racial and ethnic disparities in presentation with perforated appendicitis in children: A retrospective cohort study
The impact of COVID-19 on racial and ethnic disparities in presentation with perforated appendicitis in children: A retrospective cohort study Open
View article: The therapeutically actionable long non-coding RNA ‘T-RECS’ is essential to cancer cells’ survival in NRAS/MAPK-driven melanoma
The therapeutically actionable long non-coding RNA ‘T-RECS’ is essential to cancer cells’ survival in NRAS/MAPK-driven melanoma Open
Finding effective therapeutic targets to treat NRAS-mutated melanoma remains a challenge. Long non-coding RNAs (lncRNAs) recently emerged as essential regulators of tumorigenesis. Using a discovery approach combining experimental models an…
View article: Anti-CCL2 antibody combined with etoposide prolongs survival in a minimal residual disease mouse model of neuroblastoma
Anti-CCL2 antibody combined with etoposide prolongs survival in a minimal residual disease mouse model of neuroblastoma Open
C–C motif chemokine ligand 2 (CCL2) is a monocyte chemoattractant that promotes metastatic disease and portends a poor prognosis in many cancers. To determine the potential of anti-CCL2 inhibition as a therapy for recurrent metastatic dise…
View article: The therapeutically actionable long non-coding RNA ‘T-RECS’ is essential to cell survival in NRAS/MAPK-driven melanoma
The therapeutically actionable long non-coding RNA ‘T-RECS’ is essential to cell survival in NRAS/MAPK-driven melanoma Open
Finding effective therapeutic targets to treat NRAS-mutated melanoma remains a challenge. Long non-coding RNAs (lncRNAs) recently emerged as essential regulators of tumorigenesis. Using a discovery approach combining experimental models an…
View article: Management and Outcomes of Wilms Tumor With Suprarenal Intravascular Extension
Management and Outcomes of Wilms Tumor With Suprarenal Intravascular Extension Open
Objective: The purpose of this study was to describe management and outcomes from a contemporary cohort of children with Wilms tumor complicated by inferior vena caval thrombus. Background: The largest series of these patients was publishe…
View article: AB0546 DESIGN OF ANIFROLUMAB STUDY OF TREATMENT EFFECTIVENESS IN THE REAL WORLD (ASTER): A MULTI-NATIONAL, OBSERVATIONAL, POST-LAUNCH STUDY TO DESCRIBE THE CLINICAL EFFECTIVENESS OF ANIFROLUMAB IN ROUTINE CLINICAL PRACTICE IN PATIENTS WITH SLE
AB0546 DESIGN OF ANIFROLUMAB STUDY OF TREATMENT EFFECTIVENESS IN THE REAL WORLD (ASTER): A MULTI-NATIONAL, OBSERVATIONAL, POST-LAUNCH STUDY TO DESCRIBE THE CLINICAL EFFECTIVENESS OF ANIFROLUMAB IN ROUTINE CLINICAL PRACTICE IN PATIENTS WITH SLE Open
View article: Issue Information
Issue Information Open
View article: Epidural Analgesia Is Associated With Reduced Inpatient Opioid Consumption and Length of Stay After Wilms Tumor Resection
Epidural Analgesia Is Associated With Reduced Inpatient Opioid Consumption and Length of Stay After Wilms Tumor Resection Open
View article: A Single Center Experience With Bilateral Wilms Tumor
A Single Center Experience With Bilateral Wilms Tumor Open
Background Wilms tumor (WT) is the most common pediatric renal malignancy and bilateral disease (BWT) occurs in 5% of cases and is associated with poor outcomes. Management of BWT includes chemotherapy and oncologic resection while preserv…
View article: Giant Adrenal Myelolipoma and Congenital Adrenal Hyperplasia: a Case Report and Review of the Literature
Giant Adrenal Myelolipoma and Congenital Adrenal Hyperplasia: a Case Report and Review of the Literature Open
Introduction Adrenal myelolipomas (AMs) are rare, benign tumors without endocrine activity comprised of mature adipose and hematopoietic tissue. Surgical excision may be required for lesions which have associated symptoms, those that are g…
View article: Intercostal Nerve Cryoablation is Associated with Reduced Opioid Use in Pediatric Oncology Patients
Intercostal Nerve Cryoablation is Associated with Reduced Opioid Use in Pediatric Oncology Patients Open
View article: Effect of Combined Surgery in Patients with Complex Nanophthalmos
Effect of Combined Surgery in Patients with Complex Nanophthalmos Open
(1) Background: To evaluate the efficacy and safety of combined surgery (limited pars plana vitrectomy, anterior-chamber stabilized phacoemulsification, IOL implantation and posterior capsulotomy, LPPV + ACSP + IOL + PC) in complex nanopht…
View article: Mapping hippocampal glutamate in mesial temporal lobe epilepsy with glutamate weighted CEST (GluCEST) imaging
Mapping hippocampal glutamate in mesial temporal lobe epilepsy with glutamate weighted CEST (GluCEST) imaging Open
Temporal lobe epilepsy (TLE) is one of the most common subtypes of focal epilepsy, with mesial temporal sclerosis (MTS) being a common radiological and histopathological finding. Accurate identification of MTS during presurgical evaluation…
View article: Correction to: Outcomes Following Percutaneous Cholecystostomy Tube Placement for Acalculous Versus Calculous Cholecystitis
Correction to: Outcomes Following Percutaneous Cholecystostomy Tube Placement for Acalculous Versus Calculous Cholecystitis Open
The fourth sentence in the Results section of the abstract is correct as follows:2/24 (8.3%) AAC patients and 5/31 (16.1%)ACC patients developed recurrent cholecystitis at a median 208.0 days (IQR: 64.0-417.0)after PCT placement and 115.0 …
View article: Incidence and management of pleural effusions in patients with Wilms tumor: A Pediatric Surgical Oncology Research Collaborative study
Incidence and management of pleural effusions in patients with Wilms tumor: A Pediatric Surgical Oncology Research Collaborative study Open
Wilms tumor (WT) is the most common renal malignancy in children. Children with favorable histology WT achieve survival rates of over 90%. Twelve percent of patients present with metastatic disease, most commonly to the lungs. The presence…
View article: Factors Associated With Safe Prescription Opioid Disposal After Surgery in Adolescents
Factors Associated With Safe Prescription Opioid Disposal After Surgery in Adolescents Open
View article: The long non-coding RNA ‘TRASH’ is essential for cell survival in MAPK-driven melanoma
The long non-coding RNA ‘TRASH’ is essential for cell survival in MAPK-driven melanoma Open
MAPK-pathway up-regulation is responsible for over 40% of human cancer cases. Finding effective therapeutic targets for melanoma therapy continues to be a challenge due to drug resistance. Using a computational and experimental pipeline, w…
View article: Giant Adrenal Myelolipoma and Congenital Adrenal Hyperplasia: A Case Report and Review of the Literature
Giant Adrenal Myelolipoma and Congenital Adrenal Hyperplasia: A Case Report and Review of the Literature Open
Purpose: Adrenal myelolipomas (AMs) are rare, benign tumors without endocrine activity comprised of mature adipose and hematopoietic tissue. Surgical excision may be required for lesions which have associated symptoms, those that are growi…
View article: DNA Methylation and Transcriptomic Features are Preserved Throughout Disease Recurrence and Chemoresistance in High Grade Serous Ovarian Cancers
DNA Methylation and Transcriptomic Features are Preserved Throughout Disease Recurrence and Chemoresistance in High Grade Serous Ovarian Cancers Open
Background Little is known about the role of global DNA methylation in recurrence and chemoresistance of high grade serous ovarian cancer (HGSOC). We performed whole genome bisulfite sequencing and transcriptome sequencing in 62 primary an…