Stephanie E. Doyle
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View article: A detailed guide to melt electro-writing for tissue engineering applications
A detailed guide to melt electro-writing for tissue engineering applications Open
Melt electro-writing (MEW) is an advanced 3D printing technique with significant potential in tissue engineering due to its ability to create highly precise microscale structures using biocompatible materials. This review provides a compre…
View article: Tracking <i>in vitro</i> biodegradation dynamics in cartilage tissue engineering using dual-labeled hydrogel/scaffold composites
Tracking <i>in vitro</i> biodegradation dynamics in cartilage tissue engineering using dual-labeled hydrogel/scaffold composites Open
This study addresses the challenges of tracking cell-mediated biodegradation in cartilage tissue engineering, where hydrogels and scaffolds play a crucial role in providing structural support and promoting tissue regeneration. This researc…
View article: Optimization of 3D Extrusion-Printed Particle-Containing Hydrogels for Osteogenic Differentiation
Optimization of 3D Extrusion-Printed Particle-Containing Hydrogels for Osteogenic Differentiation Open
There is a continued increase in demand for novel bone grafting substitutes to reduce reliance on and address challenges associated with allograft and autograft bone grafts. Current synthetic bone grafting substitutes exhibit low mechanica…
View article: NEST3D printed bone-mimicking scaffolds: assessment of the effect of geometrical design on stiffness and angiogenic potential
NEST3D printed bone-mimicking scaffolds: assessment of the effect of geometrical design on stiffness and angiogenic potential Open
Tissue-engineered implants for bone regeneration require consideration regarding their mineralization and vascularization capacity. Different geometries, such as biomimetic designs and lattices, can influence the mechanical properties and …
View article: Cover Image, Volume 141, Issue 1
Cover Image, Volume 141, Issue 1 Open
The cover depicts polymeric scaffolds made of polycaprolactone and poly(lactic-co-glycolic acid) functionalized with a fluorescent molecule that monitors the scaffold's degradation for potential tissue engineering applications. The graphic…
View article: Noninvasive biosensing <scp>3D</scp> scaffold to monitor degradation: The potential of fluorescent <scp>PCL</scp> and <scp>PLGA</scp> for tissue engineering
Noninvasive biosensing <span>3D</span> scaffold to monitor degradation: The potential of fluorescent <span>PCL</span> and <span>PLGA</span> for tissue engineering Open
The nondestructive localization and traceability of polymers by fluorescent tagging has become a valuable tool for biomedical applications. Integration of fluorescent molecule to the pristine polymers could modify polymers' degradation rat…
View article: Within or Without You? A Perspective Comparing In Situ and Ex Situ Tissue Engineering Strategies for Articular Cartilage Repair
Within or Without You? A Perspective Comparing In Situ and Ex Situ Tissue Engineering Strategies for Articular Cartilage Repair Open
Human articular cartilage has a poor ability to self‐repair, meaning small injuries often lead to osteoarthritis, a painful and debilitating condition which is a major contributor to the global burden of disease. Existing clinical strategi…
View article: 3D Printed Multiphasic Scaffolds for Osteochondral Repair: Challenges and Opportunities
3D Printed Multiphasic Scaffolds for Osteochondral Repair: Challenges and Opportunities Open
Osteochondral (OC) defects are debilitating joint injuries characterized by the loss of full thickness articular cartilage along with the underlying calcified cartilage through to the subchondral bone. While current surgical treatments can…
View article: Characterization of Polycaprolactone Nanohydroxyapatite Composites with Tunable Degradability Suitable for Indirect Printing
Characterization of Polycaprolactone Nanohydroxyapatite Composites with Tunable Degradability Suitable for Indirect Printing Open
Degradable bone implants are designed to foster the complete regeneration of natural tissue after large-scale loss trauma. Polycaprolactone (PCL) and hydroxyapatite (HA) composites are promising scaffold materials with superior mechanical …
View article: Protocols for Culturing and Imaging a Human Ex Vivo Osteochondral Model for Cartilage Biomanufacturing Applications
Protocols for Culturing and Imaging a Human Ex Vivo Osteochondral Model for Cartilage Biomanufacturing Applications Open
Cartilage defects and diseases remain major clinical issues in orthopaedics. Biomanufacturing is now a tangible option for the delivery of bioscaffolds capable of regenerating the deficient cartilage tissue. However, several limitations of…