Stephanie Trezise
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View article: Antibodies elicited in humans upon chimeric hemagglutinin-based influenza virus vaccination confer FcγR-dependent protection in vivo
Antibodies elicited in humans upon chimeric hemagglutinin-based influenza virus vaccination confer FcγR-dependent protection in vivo Open
Antibody responses against highly conserved epitopes on the stalk domain of influenza virus hemagglutinin (HA) confer broad protection; however, such responses are limited. To effectively induce stalk-specific immunity against conserved HA…
View article: An arrayed CRISPR screen of primary B cells reveals the essential elements of the antibody secretion pathway
An arrayed CRISPR screen of primary B cells reveals the essential elements of the antibody secretion pathway Open
Background Humoral immunity depends on the differentiation of B cells into antibody secreting cells (ASCs). Excess or inappropriate ASC differentiation can lead to antibody-mediated autoimmune diseases, while impaired differentiation resul…
View article: Author Correction: Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance
Author Correction: Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance Open
View article: Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance
Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance Open
View article: Epigenetic modulators of B cell fate identified through coupled phenotype-transcriptome analysis
Epigenetic modulators of B cell fate identified through coupled phenotype-transcriptome analysis Open
View article: Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins
Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins Open
Antibody Secreting Cells (ASCs) are a fundamental component of humoral immunity, however, deregulated or excessive antibody production contributes to the pathology of autoimmune diseases, while transformation of ASCs results in the maligna…
View article: Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB
Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB Open