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View article: Burden of sickle cell anemia in Africa: A systematic review and meta-analysis
Burden of sickle cell anemia in Africa: A systematic review and meta-analysis Open
Introduction Sickle Cell Anemia (SCA) is a significant genetic disorder in Africa; however, comprehensive data on its prevalence and geographic distribution remain limited. We aimed to estimate the pooled prevalence of SCA (HbSS) in Africa…
View article: Prevalence of iron deficiency and iron deficiency anemia in children aged 6 - 59 months and pregnant women receiving antenatal care at Sebbi hospital, Uganda: a retrospective study
Prevalence of iron deficiency and iron deficiency anemia in children aged 6 - 59 months and pregnant women receiving antenatal care at Sebbi hospital, Uganda: a retrospective study Open
View article: Do nasogastric or nasoenteric tubes improve outcomes from adhesional small bowel obstruction: a systematic review and meta-analysis
Do nasogastric or nasoenteric tubes improve outcomes from adhesional small bowel obstruction: a systematic review and meta-analysis Open
View article: Acceptability of the RecoverEsupport Digital Health Intervention Among Patients Undergoing Breast Cancer Surgery: Qualitative Study
Acceptability of the RecoverEsupport Digital Health Intervention Among Patients Undergoing Breast Cancer Surgery: Qualitative Study Open
Background Enhanced recovery after surgery guidelines aim to optimize perioperative care and improve recovery outcomes. The guidelines contain clinician- and patient-led recommendations for pre- and postoperative care, with patient-led rec…
View article: National survey on management practices for adhesional small bowel obstruction and nasogastric tube use among general surgeons in Australia
National survey on management practices for adhesional small bowel obstruction and nasogastric tube use among general surgeons in Australia Open
Background: The nasogastric tube (NGT) is recommended routinely by current guidelines in the non-operative management of adhesional small bowel obstruction (ASBO). However, several retrospective studies have reported poorer outcomes in ASB…
View article: Phenotypic pharmacology of novel Complex I inhibitors eliciting tissue repair concurrent to control of inflammation
Phenotypic pharmacology of novel Complex I inhibitors eliciting tissue repair concurrent to control of inflammation Open
View article: Wait times for breast cancer surgery in lean and traditional care pathways: a multi-group path analysis
Wait times for breast cancer surgery in lean and traditional care pathways: a multi-group path analysis Open
Conducting the biopsy immediately after an abnormal mammogram, improving wait times for MRIs, and improving access for rural patients may be important areas of change-related focus. Shorter wait times to breast cancer surgery in the lean p…
View article: Prevalence of sickle cell anemia in Africa: A protocol for a meta-analysis of existing studies
Prevalence of sickle cell anemia in Africa: A protocol for a meta-analysis of existing studies Open
Background Sickle cell anemia (SCA) rank 11th among all causes of mortality in Sub-Saharan Africa, with the region accounting for 75% of global cases. Inconsistent diagnostic methods and country-specific data gaps hinder current prevalence…
View article: Study protocol of a pilot randomised controlled trial assessing the feasibility and acceptability of RecoverEsupport: a digital health intervention to enhance recovery in women undergoing surgery for breast cancer
Study protocol of a pilot randomised controlled trial assessing the feasibility and acceptability of RecoverEsupport: a digital health intervention to enhance recovery in women undergoing surgery for breast cancer Open
Introduction Internationally, breast cancer is the second most diagnosed cancer with approximately 2.3 million people diagnosed each year. 40% will require a mastectomy which has an average length of hospital stay of 1–2 days. Enhanced Rec…
View article: Interventional factors influencing natural killer cell immunity in colorectal cancer: a systematic review
Interventional factors influencing natural killer cell immunity in colorectal cancer: a systematic review Open
View article: The Nasogastric Tube for Adhesional Small Bowel Obstruction: An Analysis of Treatment Effect and Outcomes in a Tertiary Acute General Surgical Unit
The Nasogastric Tube for Adhesional Small Bowel Obstruction: An Analysis of Treatment Effect and Outcomes in a Tertiary Acute General Surgical Unit Open
View article: Effect on Response Rates of Adding a QR Code to Patient Consent Forms for Qualitative Research in Patients With Cancer: Pilot Randomized Controlled Trial
Effect on Response Rates of Adding a QR Code to Patient Consent Forms for Qualitative Research in Patients With Cancer: Pilot Randomized Controlled Trial Open
Background The successful conduct of health and medical research is largely dependent on participant recruitment. Effective, yet inexpensive methods of increasing response rates for all types of research are required. QR codes are now comm…
View article: In Holistic Admissions, a Combination of Non-Academic Explanatory Variables Has Significant Predictive Value for Applicant Ranking
In Holistic Admissions, a Combination of Non-Academic Explanatory Variables Has Significant Predictive Value for Applicant Ranking Open
A medical school with a focus on community engagement has innovated its admissions process to include three different interview formats and one novel task format. Each component is designed to assess specific attributes of applicants, incl…
View article: PACIENTE COM ANEMIA APLÁSICA E CLONE DE HEMOGLOBINÚRIA PAROXÍSTICA NOTURNA EVOLUINDO PARA LEUCEMIA MIELOIDE AGUDA.
PACIENTE COM ANEMIA APLÁSICA E CLONE DE HEMOGLOBINÚRIA PAROXÍSTICA NOTURNA EVOLUINDO PARA LEUCEMIA MIELOIDE AGUDA. Open
Objetivo: A hemoglobinúria paroxística noturna (HPN) é uma doença cuja fisiopatologia decorre de um defeito mutacional em um clone de célula tronco hematopoiética. Esta mutação ocorre no gene da fosfaditilinositollglicana, que resulta no b…
View article: AVALIAÇÃO DO PERFIL EPIDEMIOLÓGICO DAS LEUCEMIAS MIELOIDES AGUDAS NO HOSPITAL UNIVERSITÁRIO ANTÔNIO PEDRO
AVALIAÇÃO DO PERFIL EPIDEMIOLÓGICO DAS LEUCEMIAS MIELOIDES AGUDAS NO HOSPITAL UNIVERSITÁRIO ANTÔNIO PEDRO Open
Objetivo: A Leucemia mieloide aguda (LMA), é uma neoplasia que afeta a medula óssea a apresenta um curso agressivo. Com isso, é fundamental o diagnóstico precoce e respectivo tratamento. O prognóstico está intimamente relacionado às caract…
View article: The Microleaks study: 16S community profile and metagenomic shotgun sequencing signatures associated with anastomotic leak
The Microleaks study: 16S community profile and metagenomic shotgun sequencing signatures associated with anastomotic leak Open
Anastomotic leaks (AL) are the most severe complications of colorectal surgery. The cause of AL is unclear, but recent studies have implicated the intestinal microbiota in its development. We aimed to determine whether there is an identifi…
View article: Oral antibiotics and mechanical bowel preparation in elective colorectal resections: bridging the gap in colorectal surgery protocols
Oral antibiotics and mechanical bowel preparation in elective colorectal resections: bridging the gap in colorectal surgery protocols Open
Data S1 Document S1 (List of trial investigators). Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be dir…
View article: VTE prophylaxis for major abdominal surgery: A hospital audit and nurses' survey for quality improvement
VTE prophylaxis for major abdominal surgery: A hospital audit and nurses' survey for quality improvement Open
Objective: The objective of this study is to assess and improve VTE prophylaxis practices in major abdominal surgery through a hospital audit and nurses' survey. Primary aims: Evaluate adherence to VTE prophylaxis guidelines in abdominal s…
View article: The impact of a regionally based translational cancer research collaborative in Australia using the FAIT methodology
The impact of a regionally based translational cancer research collaborative in Australia using the FAIT methodology Open
Background Translating research, achieving impact, and assessing impact are important aspirations for all research collaboratives but can prove challenging. The Hunter Cancer Research Alliance (HCRA) was funded from 2014 to 2021 to enhance…
View article: The Microleaks study: 16S community profile and metagenomic shotgun sequencing signatures associated with anastomotic leak
The Microleaks study: 16S community profile and metagenomic shotgun sequencing signatures associated with anastomotic leak Open
Anastomotic leaks (AL) are the most severe complications of colorectal surgery. The cause of AL is unclear, but recent studies have implicated the intestinal microbiota in its development. We aimed to determine whether there is an identifi…
View article: Should intermittent pneumatic compression devices be standard therapy for the prevention of venous thromboembolic events in major surgery? Protocol for a randomised clinical trial (IMPOSTERS)
Should intermittent pneumatic compression devices be standard therapy for the prevention of venous thromboembolic events in major surgery? Protocol for a randomised clinical trial (IMPOSTERS) Open
Introduction Venous thromboembolism (VTE) is a recognised postsurgical risk. Current prevention methods involve low molecular weight heparin (LMWH), graduated compression stockings (GCS), and intermittent pneumatic compression devices (IPC…
View article: Optimal antiseptic skin preparation agents for minimizing surgical site infection following surgery: cost and cost-effectiveness analysis
Optimal antiseptic skin preparation agents for minimizing surgical site infection following surgery: cost and cost-effectiveness analysis Open
Background The application of antiseptic skin agents prior to incision minimizes the rate of surgical site infection. Despite their ubiquity, the optimal skin preparation agent remains uncertain. A retrospective economic analysis was condu…
View article: Venous thromboembolic prophylaxis: current practice of surgeons in Australia and New Zealand for major abdominal surgery
Venous thromboembolic prophylaxis: current practice of surgeons in Australia and New Zealand for major abdominal surgery Open
View article: Protocol paper for SMART OPS: Shared decision-making Multidisciplinary Approach – a Randomised controlled Trial in the Older adult Population considering Surgery
Protocol paper for SMART OPS: Shared decision-making Multidisciplinary Approach – a Randomised controlled Trial in the Older adult Population considering Surgery Open
Introduction The Australian population presenting with surgical pathology is becoming older, frailer and more comorbid. Shared decision-making is rapidly becoming the gold standard of care for patients considering high-risk surgery to ensu…
View article: A pilot study: intraoperative <scp>16S rRNA</scp> sequencing versus culture in predicting colorectal incisional surgical site infection
A pilot study: intraoperative <span>16S rRNA</span> sequencing versus culture in predicting colorectal incisional surgical site infection Open
Background Surgical Site Infection (SSI) of the abdominal incision is a dreaded complication following colorectal surgery. Identifying the intraoperative surgical site microbes may provide clarity in the pathogenesis of SSIs. Genomic seque…
View article: Effectiveness and cost-effectiveness of a digital health intervention to support patients with colorectal cancer prepare for and recover from surgery: study protocol of the RecoverEsupport randomised controlled trial
Effectiveness and cost-effectiveness of a digital health intervention to support patients with colorectal cancer prepare for and recover from surgery: study protocol of the RecoverEsupport randomised controlled trial Open
Introduction Surgery is the most common treatment for colorectal cancer (CRC) and can cause relative long average length of stay (LOS) and high risks of unplanned readmissions and complications. Enhanced Recovery After Surgery (ERAS) pathw…
View article: Perceived Provision of Perioperative Information and Care by Patients Who Have Undergone Surgery for Colorectal Cancer: A Cross-Sectional Study
Perceived Provision of Perioperative Information and Care by Patients Who Have Undergone Surgery for Colorectal Cancer: A Cross-Sectional Study Open
Background: Active patient participation in preparation and recovery from colorectal cancer surgery can be facilitated by timely information and care and may improve patient wellbeing and reduce hospitalizations; Methods: We aimed to ident…
View article: Efficacy of intermittent compression devices for thromboembolic prophylaxis in major abdominal surgery: a systematic review and meta‐analysis
Efficacy of intermittent compression devices for thromboembolic prophylaxis in major abdominal surgery: a systematic review and meta‐analysis Open
Background The benefits of mechanical prophylaxis for the prevention of venous thromboembolism (VTE) in abdominal and pelvic surgery are uncertain, with different guidelines stating that graduated compression stockings (GCS) and intermitte…
View article: Machine Learning Prediction of Adenovirus D8 Conjunctivitis Complications from Viral Whole-Genome Sequence
Machine Learning Prediction of Adenovirus D8 Conjunctivitis Complications from Viral Whole-Genome Sequence Open
View article: Attitudes towards Enhanced Recovery after Surgery (ERAS) interventions in colorectal surgery: nationwide survey of Australia and New Zealand colorectal surgeons
Attitudes towards Enhanced Recovery after Surgery (ERAS) interventions in colorectal surgery: nationwide survey of Australia and New Zealand colorectal surgeons Open
Background Whilst Enhanced Recovery after Surgery (ERAS) has been widely accepted in the international colorectal surgery community, there remains significant variations in ERAS programme implementations, compliance rates and best practice…