Explanipedia

Implementation of Lecanemab for Alzheimer's Disease Within the Veterans Health Administration: Facilitators and Barriers Open

Alison O’Donnell, A. Fortunato, Naveen M. Reddy, Shaye A Kerper, Steven M. Handler · 2025

Background Several amyloid targeting therapies have been approved for Alzheimer's disease (AD), including lecanemab (Leqembi). However, real‐world implementation of these drugs has uncovered significant challenges. Methods We conducted a n…

Kinetics of <span>SARS</span> ‐ <span>CoV</span> ‐2 Shedding in Nursing Home Residents and Staff Open

Morgan J. Katz, Majerle Reeves, Tiffany G. Harris, Jazmin Duque, Scott K. Fridkin , et al. · 2025

Background Nursing homes (NHs) were disproportionately affected by the COVID‐19 pandemic. However, little is known regarding the kinetics of SARS‐CoV‐2 shedding in NH residents and staff, which could inform treatment and infection preventi…

P-2355. Etiology and symptoms of respiratory tract infections among nursing home residents: Results from multiplex respiratory pathogen testing in the Nursing Home Public Health Response Network, February – April, 2024, United States Open

Alfonso C. Hernandez‐Romieu, Tiffany G. Harris, Sujan Reddy, Yasin Abul, David H. Canaday , et al. · 2025

Background Respiratory tract infections (RTI) cause high morbidity and mortality among nursing home (NH) residents, yet their etiology and frequency remain understudied. We implemented multiplex respiratory panel (MRP) testing to describe …

Digital Health Readiness: Making Digital Health Care More Inclusive Open

Timothy Bober, Bruce L. Rollman, Steven M. Handler, Andrew Watson, Lyndsay A. Nelson , et al. · 2024

This paper proposes an approach to assess digital health readiness in clinical settings to understand how prepared, experienced, and equipped individual people are to participate in digital health activities. Existing digital health litera…

Viral Kinetics of SARS-CoV-2 in Nursing Home Residents and Staff Open

Majerle Reeves, Scott K. Fridkin, Rachel B. Slayton, Yasin Abul, Christopher J. Crnich , et al. · 2024

Background: Nursing home (NH) residents are at high risk of COVID-19 from exposure to infected staff and other residents. Understanding SARS-CoV-2 viral RNA kinetics in residents and staff can guide testing, isolation, and return to work r…

Antimicrobial Use in Veterans Affairs Community Living Centers, 2015 - 2019 Open

C. David Dalton, Tina Willson, Brigid Wilson, Taissa Bej, Nadim El Chakhtoura , et al. · 2024

Background: Optimizing antimicrobial use (AU) among post-acute and long-term care (PALTC) residents is fundamental to reducing the morbidity and mortality associated with multidrug-resistant organism (MDROs), as well as unintended social c…

Factors Associated With the Ability of US Nursing Homes to Accept Residents With Severe Obesity Open

Cynthia McMahan, Bianca Shieu, Alison M. Trinkoff, Nicholas G. Castle, David G. Wolf , et al. · 2024

The decline in acceptance of residents with severe obesity during and after COVID-19 highlights potential challenges that this population faces in accessing care. Our results also raise concerns that an intersection of disparities may exis…

Excision of a vaginal cuff nodule in 9 steps Open

Victoria Buckley, Bethany Malone, S Simko, Steven M. Handler, Samar Nahas , et al. · 2024

Case report on evacuation of retropubic hematoma after previous transvaginal retropubic sling placement Open

Minh-Quyen Lê, Golnaz Namazi, H. Aubert, Steven M. Handler, Mallory Stuparich · 2024

Kinetics of SARS-CoV-2 Shedding in Nursing Home Residents and Staff Open

Morgan J. Katz, Majerle Reeves, Tiffany G. Harris, Jazmin Duque, Scott K. Fridkin , et al. · 2024

Telehealth with older adults: Getting it right Open

Kevin Biese, Steven M. Handler, Liane Wardlow, Zia Agha · 2022

This editorial comments on the article by Bhatia et al . in this issue.

Falls prediction using the nursing home minimum dataset Open

Richard D. Boyce, Olga Kravchenko, Subashan Perera, Jordan F. Karp, Sandra L. Kane‐Gill , et al. · 2022

Objective The purpose of the study was to develop and validate a model to predict the risk of experiencing a fall for nursing home residents utilizing data that are electronically available at the more than 15 000 facilities in the United …

The Challenge of Severe Obesity in Nursing Homes from the Perspective of Administrators Open

John A. Harris, Bianca Shieu, Alison M. Trinkoff, Steven M. Handler, Nicholas G. Castle , et al. · 2022

Development of High-Risk Geriatric Polypharmacy Electronic Clinical Quality Measures and a Pilot Test of EHR Nudges Based on These Measures Open

Stephen D. Persell, Tiffany Brown, Jason N. Doctor, Craig R. Fox, Noah J. Goldstein , et al. · 2022

Women with Obesity Are More Likely to Have Long-Term Indwelling Bladder Catheterization in U.S. Nursing Homes Open

John A. Harris, Mary F. Ackenbom, Alison M. Trinkoff, Steven M. Handler, John Engberg , et al. · 2021

Reducing indwelling catheters and increasing clean intermittent catheterization is a key element of effective infection control and maintaining functional independence in nursing homes. Nursing care is often more difficult as obesity incre…

Introduction of the BNT162b2 vaccine during a COVID-19 nursing home outbreak Open

M. Catherine McEllistrem, Cornelius J. Clancy, Deanna J. Buehrle, Aaron Lucas, Jennifer Pruskowski , et al. · 2021

Qualitative Assessment of Resident Obesity in Nursing Homes by Medical Providers Open

John A. Harris, Steven M. Handler, Alison M. Trinkoff, David C. Wolf, Nicholas G. Castle · 2020

We present qualitative themes from an ongoing five-year AHRQ-funded project (R01HS026943) examining the various ways nursing homes provide care for residents with obesity to determine the most effective way to prevent adverse safety events…

Innovation Through Regulation: COVID-19 and the Evolving Utility of Telemedicine Open

Suzanne M. Gillespie, Steven M. Handler, Alex Bardakh · 2020

Adverse Events in Long-term Care Residents Transitioning From Hospital Back to Nursing Home Open

Alok Kapoor, Terry S. Field, Steven M. Handler, Kimberly A. Fisher, Cassandra Saphirak , et al. · 2019

Adverse events developed in nearly 4 of 10 of discharges from hospital back to LTC. Most were preventable or ameliorable. Standardized reporting of events and better coordination and information transfer across settings are potential ways …

How CMS Helped a Telemedicine Company Get Its Footing Open

Steven M. Handler · 2018

Nursing Home Provider Perceptions of Telemedicine for Providing Specialty Consults Open

Julia Driessen, Woody Chang, Palak Patel, Rollin Wright, Kambria Ernst , et al. · 2018

The responses of NH providers suggest support for the concept of telemedicine as a modality of care that can be used to offer specialty consults to NH residents.

Use of Telemedicine to Enhance Pharmacist Services in the Nursing Facility Open

Sandra L. Kane‐Gill, Joshua D. Niznik, John A. Kellum, Colleen M. Culley, Richard D. Boyce , et al. · 2017

There is a general paucity of practice-related research to demonstrate potential benefits of pharmacists' services incorporating telemedicine. Telemedicine may be a resource-efficient approach to enhance pharmacist services in the nursing …

The Discussion to Ensure the Patient-Centered, Health-Focused, Prognosis-Appropriate, and Rational Medication Regimen (DE-PHARM) Quality Improvement Project—Rational Deprescribing in Residents with Life-Limiting Illness (FR420A) Open

Jennifer Pruskowski, Steven M. Handler · 2017

Physician Perceptions of Consultant Pharmacist Services Associated with an Intervention for Adverse Drug Events in the Nursing Facility Open

SandraL. Kane-Gill, J. William Hanlon, MichaelJ. Fine, Subashan Perera, ColleenM. Culley , et al. · 2016

ADE = Adverse drug event, M = Statistically significant mean, RCT = Randomized controlled trial, SBAR = Situation, Background, Discussion, Recommendation, SD = Standard deviation.

Preparing Nursing Home Data from Multiple Sites for Clinical Research – A Case Study Using Observational Health Data Sciences and Informatics Open

Richard D. Boyce, Steven M. Handler, Jordan F. Karp, Subashan Perera, Charles F. Reynolds · 2016

Introduction: A potential barrier to nursing home research is the limited availability of research quality data in electronic form. We describe a case study of converting electronic health data from five skilled nursing facilities to a res…

Using mobile health technology to deliver decision support for self-monitoring after lung transplantation Open

Yun Jiang, Susan M. Sereika, Annette DeVito Dabbs, Steven M. Handler, Elizabeth A. Schlenk · 2016

Acceptance and Use of Mobile Technology for Health Self-Monitoring in Lung Transplant Recipients during the First Year Post-Transplantation Open

Susan M. Sereika, Annette DeVito Dabbs, Steven M. Handler, Elizabeth A. Schlenk, Yun Jiang · 2016

Summary To describe lung transplant recipients (LTRs’) acceptance and use of mobile technology for health self-monitoring during the first year post-transplantation, and explore correlates of the use of technology in the 0 to 2, >2 to ≤6, …

Nursing Home Provider Perceptions of Telemedicine for Reducing Potentially Avoidable Hospitalizations Open

Julia Driessen, Andro Bonhomme, Woody Chang, David A. Nace, Dio Kavalieratos , et al. · 2016

Clinical decision support for drug related events: Moving towards better prevention Open

Sandra L. Kane‐Gill, Archita Achanta, John A. Kellum, Steven M. Handler · 2016

Clinical decision support (CDS) systems with automated alerts integrated into electronic medical records demonstrate efficacy for detecting medication errors (ME) and adverse drug events (ADEs). Critically ill patients are at increased ris…

Using a Clinical Surveillance System to Detect Drug‐Associated Hypoglycemia in Nursing Home Residents Open

Colleen M. Culley, Subashan Perera, Zachary A. Marcum, Sandra L. Kane‐Gill, Steven M. Handler · 2015

Objectives To determine whether a clinical surveillance system could be used to detect drug‐associated hypoglycemia events and determine their incidence in nursing home ( NH ) residents. Design Retrospective cohort. Setting Four NH s in we…

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