Stephen E. Jones
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Efficient Whole-Brain Quantitative Magnetization Transfer Imaging at 3T Using Segmented EPI Readout with Variable Power Magnetization Transfer Pulses (EP-vpMT) Open
Quantitative magnetization transfer (qMT) imaging is sensitive to myelin-related macromolecular content and brain microstructure but is limited by long scan times. We present a fast, SAR-efficient qMT technique using a segmented echo-plana…
Brain MRI for the diagnosis of dementia in low- and middle-income countries: a systematic review and meta-analysis protocol of diagnostic utility and imaging findings Open
Introduction The utility of brain MRI in dementia diagnosis offers critical insights into structural brain changes, such as hippocampal and thalamic atrophy, which are hallmark features of Alzheimer’s disease and Alzheimer’s disease-relate…
Impact of a pharmacy care management service on cardiometabolic medication adherence and resource use for Medicare Advantage beneficiaries Open
Compared with well-matched controls, PCM patients with cardiometabolic disease had significantly higher rates of medication adherence and significantly lower hospitalization rates during the 12-month follow-up period. This effect was great…
Long-Term Safety of Vedolizumab in Patients With Ulcerative Colitis/Crohn’s Disease: A Prospective Observational Study Open
There was no new safety signal identified in relation to vedolizumab. Results regarding safety and effectiveness were consistent with the known profile of vedolizumab.
View article: Volumetric <scp>MRI</scp> Comparing Longitudinal Change in <scp>MOGAD</scp> to <scp>NMOSD</scp> , <scp>MS</scp> and Healthy Controls, and Disability Associations
Volumetric <span>MRI</span> Comparing Longitudinal Change in <span>MOGAD</span> to <span>NMOSD</span> , <span>MS</span> and Healthy Controls, and Disability Associations Open
Objectives To examine volumetric magnetic resonance imaging (vMRI) in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD), compared to multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and healthy…
View article: Impact of reference equations on lung function and outcomes in fibrotic interstitial lung disease
Impact of reference equations on lung function and outcomes in fibrotic interstitial lung disease Open
Background The impact of applying different lung function reference equations and interpretation methods in fibrotic interstitial lung disease (ILD) is poorly understood. We aimed to evaluate disease severity classification, trajectories a…
Positive Integrands from Feynman Integrals in the Minkowski Regime Open
We present a method for rewriting dimensionally regulated Feynman parameter integrals in the Minkowski regime as a sum of real, positive integrands multiplied by complex prefactors. This representation eliminates the need for contour defor…
View article: Protocol of a randomized, single-blind, controlled trial of an 18-month, home-based, high-intensity, exercise intervention in older, cognitively unimpaired APOE ε4 carriers
Protocol of a randomized, single-blind, controlled trial of an 18-month, home-based, high-intensity, exercise intervention in older, cognitively unimpaired APOE ε4 carriers Open
Background The World Health Organization highlighted the potential protective role of exercise against cognitive decline, all-cause dementia, Alzheimer’s disease (AD), and vascular dementia in healthy individuals. We have previously shown …
Impact of a Pharmacy Care Management Service on Cardiometabolic Medication Adherence and Resource Use for Medicare Advantage Beneficiaries Open
BACKGROUND Prescribing rates and adherence to evidence-based cardiometabolic medications remain suboptimal. Many strategies to improve prescribing and adherence have been developed; pharmacy care management (PCM) programs are among the mos…
View article: The effectiveness and risks of Treating people with Idiopathic Pulmonary fibrosis with the Addition of Lansoprazole (TIPAL): study protocol for a randomised placebo-controlled multicentre clinical trial
The effectiveness and risks of Treating people with Idiopathic Pulmonary fibrosis with the Addition of Lansoprazole (TIPAL): study protocol for a randomised placebo-controlled multicentre clinical trial Open
Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrotic lung disease frequently complicated by gastro-oesophageal reflux disease. Although several observational studies and a pilot study have investigated the rol…
Perceptions and practices of imaging personnel and physicians regarding the use of brain MRI for dementia diagnosis in Uganda Open
Introduction Diagnosing dementia remains challenging in low-income settings due to limited diagnostic options and the absence of definitive biomarkers. The use of brain MRI in the diagnosis of dementia is infrequent in Uganda, and even whe…
View article: Multiparametric Characterization of Focal Cortical Dysplasia Using <scp>3D MR</scp> Fingerprinting
Multiparametric Characterization of Focal Cortical Dysplasia Using <span>3D MR</span> Fingerprinting Open
Objective To develop a multiparametric machine‐learning (ML) framework using high‐resolution 3 dimensional (3D) magnetic resonance (MR) fingerprinting (MRF) data for quantitative characterization of focal cortical dysplasia (FCD). Material…
View article: Cerebral Amyloid Angiopathy in Patients with Cognitive Impairment: Cerebrospinal Fluid Biomarkers
Cerebral Amyloid Angiopathy in Patients with Cognitive Impairment: Cerebrospinal Fluid Biomarkers Open
Introduction: Cerebral amyloid angiopathy (CAA) is characterized by amyloid β (Aβ) deposition in brain vessels, leading to hemorrhagic phenomena and cognitive impairment. Magnetic resonance imaging (MRI)-based criteria allow a diagnosis of…
High-resolution diffusion tensor imaging of the fornix predicts memory function in multiple sclerosis Open
Background Cognitive dysfunction is a known symptom of multiple sclerosis (MS), with memory recognized as a frequently impacted domain. Here, we used high-resolution MRI at 7 tesla to build on cross-sectional work by evaluating the longitu…
Combining <span>magnetic resonance</span> fingerprinting with voxel‐based morphometric analysis to reduce false positives for focal cortical dysplasia detection Open
Objective We aim to improve focal cortical dysplasia (FCD) detection by combining high‐resolution, three‐dimensional (3D) magnetic resonance fingerprinting (MRF) with voxel‐based morphometric magnetic resonance imaging (MRI) analysis. Meth…
The on-shell expansion: from Landau equations to the Newton polytope Open
A bstract We study the application of the method of regions to Feynman integrals with massless propagators contributing to off-shell Green’s functions in Minkowski spacetime (with non-exceptional momenta) around vanishing external masses, …
Impact of a Pharmacy Care Management Service on Health Spending, Resource Use, and Medication Adherence for Medically Complex Medicare Advantage Members Open
BACKGROUND The Medicare Advantage (MA) program has grown rapidly over the past two decades, particularly among medically complex beneficiaries, which has implications for healthcare utilization, costs, and quality in the MA program. Ensuri…
View article: Supplementary Figure 3 from Patients with Slowly Proliferative Early Breast Cancer Have Low Five-Year Recurrence Rates in a Phase III Adjuvant Trial of Capecitabine
Supplementary Figure 3 from Patients with Slowly Proliferative Early Breast Cancer Have Low Five-Year Recurrence Rates in a Phase III Adjuvant Trial of Capecitabine Open
Figure S3: Forest plots for DFS comparing patients with central Ki-67 high versus low based on quartile cutoffs (exploratory analysis) in (A) ER-positive/HER2-negative breast cancer (n=824) and (B) TNBC (n=454)
View article: Supplementary Figure 2 from Patients with Slowly Proliferative Early Breast Cancer Have Low Five-Year Recurrence Rates in a Phase III Adjuvant Trial of Capecitabine
Supplementary Figure 2 from Patients with Slowly Proliferative Early Breast Cancer Have Low Five-Year Recurrence Rates in a Phase III Adjuvant Trial of Capecitabine Open
Figure S2: Distribution of central Ki-67 scores in (A) ER-positive/HER2-negative breast cancer (n=824) and (B) TNBC (n=454)
View article: Supplementary Tables S1-5 from Patients with Slowly Proliferative Early Breast Cancer Have Low Five-Year Recurrence Rates in a Phase III Adjuvant Trial of Capecitabine
Supplementary Tables S1-5 from Patients with Slowly Proliferative Early Breast Cancer Have Low Five-Year Recurrence Rates in a Phase III Adjuvant Trial of Capecitabine Open
Supplementary Tables S1-5. Table S1. Baseline demographic and disease characteristics of patients with central Ki-67 data available. Table S2. Concordance between central and local Ki-67 scores. Table S3. Percentage of patients with a DFS …
View article: Supplementary Figure 3 from Patients with Slowly Proliferative Early Breast Cancer Have Low Five-Year Recurrence Rates in a Phase III Adjuvant Trial of Capecitabine
Supplementary Figure 3 from Patients with Slowly Proliferative Early Breast Cancer Have Low Five-Year Recurrence Rates in a Phase III Adjuvant Trial of Capecitabine Open
Figure S3: Forest plots for DFS comparing patients with central Ki-67 high versus low based on quartile cutoffs (exploratory analysis) in (A) ER-positive/HER2-negative breast cancer (n=824) and (B) TNBC (n=454)
View article: Supplementary Figure 1 from Patients with Slowly Proliferative Early Breast Cancer Have Low Five-Year Recurrence Rates in a Phase III Adjuvant Trial of Capecitabine
Supplementary Figure 1 from Patients with Slowly Proliferative Early Breast Cancer Have Low Five-Year Recurrence Rates in a Phase III Adjuvant Trial of Capecitabine Open
Figure S1: Forest plot of hazard ratios by subgroup in the ITT population (planned analysis) for (A) DFS and (B) OS
View article: Supplementary Figure 1 from Patients with Slowly Proliferative Early Breast Cancer Have Low Five-Year Recurrence Rates in a Phase III Adjuvant Trial of Capecitabine
Supplementary Figure 1 from Patients with Slowly Proliferative Early Breast Cancer Have Low Five-Year Recurrence Rates in a Phase III Adjuvant Trial of Capecitabine Open
Figure S1: Forest plot of hazard ratios by subgroup in the ITT population (planned analysis) for (A) DFS and (B) OS
View article: Data from Patients with Slowly Proliferative Early Breast Cancer Have Low Five-Year Recurrence Rates in a Phase III Adjuvant Trial of Capecitabine
Data from Patients with Slowly Proliferative Early Breast Cancer Have Low Five-Year Recurrence Rates in a Phase III Adjuvant Trial of Capecitabine Open
Purpose: We conducted a randomized phase III study to determine whether patients with early breast cancer would benefit from the addition of capecitabine (X) to a standard regimen of doxorubicin (A) plus cyclophosphamide (C) followed by do…
View article: Supplementary Figure 2 from Patients with Slowly Proliferative Early Breast Cancer Have Low Five-Year Recurrence Rates in a Phase III Adjuvant Trial of Capecitabine
Supplementary Figure 2 from Patients with Slowly Proliferative Early Breast Cancer Have Low Five-Year Recurrence Rates in a Phase III Adjuvant Trial of Capecitabine Open
Figure S2: Distribution of central Ki-67 scores in (A) ER-positive/HER2-negative breast cancer (n=824) and (B) TNBC (n=454)