Stephen G. Chun
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View article: PROTON VERSUS PHOTON RADIATION TO IMMUNE CELLS AND ORGANS-AT-RISK IN LA-NSCLC: DOSIMETRIC ANALYSIS OF RTOG 1308, A PHASE III RCT
PROTON VERSUS PHOTON RADIATION TO IMMUNE CELLS AND ORGANS-AT-RISK IN LA-NSCLC: DOSIMETRIC ANALYSIS OF RTOG 1308, A PHASE III RCT Open
View article: Bayesian Learning to Reduce Cardiac Risk for Locally Advanced NSCLC Patients Based on Personalized Radiotherapy Prescription
Bayesian Learning to Reduce Cardiac Risk for Locally Advanced NSCLC Patients Based on Personalized Radiotherapy Prescription Open
Purpose Radiation-induced heart damage is a significant concern in the treatment of non-small cell lung cancer (NSCLC) that can have debilitating or life-threatening consequences. Current strategies focus on minimizing heart exposure, but …
View article: 1489 REStoring lymphoCytes using NKTR-255 after chemoradiothErapy in solid tumors (RESCUE): preplanned interim safety and efficacy analysis
1489 REStoring lymphoCytes using NKTR-255 after chemoradiothErapy in solid tumors (RESCUE): preplanned interim safety and efficacy analysis Open
View article: Salvage Reirradiation with Proton Beam Therapy for Locoregionally Recurrent Non-Small Cell Lung Cancer
Salvage Reirradiation with Proton Beam Therapy for Locoregionally Recurrent Non-Small Cell Lung Cancer Open
Background/Objectives: This retrospective study evaluates outcomes of 66 patients who underwent reirradiation (re-RT) with proton beam therapy (PBT) for recurrent non-small cell lung cancer. Methods: Toxicity was scored via the CTCAE v5.0,…
View article: Accelerated Hypofractionated Radiotherapy for Locally Advanced NSCLC: A Systematic Review From the International Association for the Study of Lung Cancer Advanced Radiation Technology Subcommittee
Accelerated Hypofractionated Radiotherapy for Locally Advanced NSCLC: A Systematic Review From the International Association for the Study of Lung Cancer Advanced Radiation Technology Subcommittee Open
View article: American Radium Society Appropriate Use Criteria on Cardiac Toxicity Prevention and Management After Thoracic Radiotherapy
American Radium Society Appropriate Use Criteria on Cardiac Toxicity Prevention and Management After Thoracic Radiotherapy Open
View article: Appropriate Use Criteria (AUC) for the Management of Non-Small Cell Lung Cancer in a Central/Ultra-Central Location: Guidelines from the American Radium Society
Appropriate Use Criteria (AUC) for the Management of Non-Small Cell Lung Cancer in a Central/Ultra-Central Location: Guidelines from the American Radium Society Open
View article: Long-Term Prospective Outcomes of Intensity Modulated Radiotherapy for Locally Advanced Lung Cancer
Long-Term Prospective Outcomes of Intensity Modulated Radiotherapy for Locally Advanced Lung Cancer Open
Importance The optimal radiotherapy technique for unresectable locally advanced non–small cell lung cancer (NSCLC) is controversial, so evaluating long-term prospective outcomes of intensity-modulated radiotherapy (IMRT) is important. Obje…
View article: American Radium Society Appropriate Use Criteria for Unresectable Locally Advanced Non–Small Cell Lung Cancer
American Radium Society Appropriate Use Criteria for Unresectable Locally Advanced Non–Small Cell Lung Cancer Open
Importance The treatment of locally advanced non–small cell lung cancer (LA-NSCLC) has been informed by more than 5 decades of clinical trials and other relevant literature. However, controversies remain regarding the application of variou…
View article: Metformin in Conjunction With Stereotactic Radiotherapy for Early-stage Non-small Cell Lung Cancer: Long-term Results of a Prospective Phase II Clinical Trial
Metformin in Conjunction With Stereotactic Radiotherapy for Early-stage Non-small Cell Lung Cancer: Long-term Results of a Prospective Phase II Clinical Trial Open
Outcomes of SBRT and metformin for early-stage NSCLC were similar to historic controls. These findings along with the results of the NRG-LU001 and OCOG randomized trials do not support the therapeutic use of metformin for NSCLC.
View article: Endoscopic Ultrasound-Guided Fiducial Placement for Stereotactic Body Radiation Therapy in Patients with Pancreatic Cancer
Endoscopic Ultrasound-Guided Fiducial Placement for Stereotactic Body Radiation Therapy in Patients with Pancreatic Cancer Open
Accurate delivery of stereotactic body radiotherapy (SBRT) to pancreatic tumors relies on successful EUS-guided placement of fiducial markers. The aim of this study is to report the technical feasibility and safety of EUS-guided fiducial p…
View article: P2.01-07 Restoring Lymphocytes Using NKTR-255 after Chemoradiotherapy in Solid Tumors (RESCUE)
P2.01-07 Restoring Lymphocytes Using NKTR-255 after Chemoradiotherapy in Solid Tumors (RESCUE) Open
View article: A phase II clinical trial of frameless, fractionated stereotactic radiation therapy for brain metastases
A phase II clinical trial of frameless, fractionated stereotactic radiation therapy for brain metastases Open
Stereotactic radiation therapy yields high rates of local control for brain metastases, but patients in rural or suburban areas face geographic and socioeconomic barriers to its access. We conducted a phase II clinical trial of frameless, …
View article: Peripheral T-Cell Priming and Micrometastatic Disease Control with Metastasis-Directed Therapy: Multidimensional Immunogenomic Profiling of Oligometastatic Prostate Cancer in the EXTEND Trial
Peripheral T-Cell Priming and Micrometastatic Disease Control with Metastasis-Directed Therapy: Multidimensional Immunogenomic Profiling of Oligometastatic Prostate Cancer in the EXTEND Trial Open
View article: Stereotactic ablative radiotherapy with or without immunotherapy for early-stage or isolated lung parenchymal recurrent node-negative non-small-cell lung cancer: an open-label, randomised, phase 2 trial
Stereotactic ablative radiotherapy with or without immunotherapy for early-stage or isolated lung parenchymal recurrent node-negative non-small-cell lung cancer: an open-label, randomised, phase 2 trial Open
View article: American Radium Society Appropriate Use Criteria for Radiation Therapy in the Multidisciplinary Management of Thymic Carcinoma
American Radium Society Appropriate Use Criteria for Radiation Therapy in the Multidisciplinary Management of Thymic Carcinoma Open
Importance Thymic carcinoma is rare, and its oncologic management is controversial due to a paucity of prospective data. For this reason, multidisciplinary consensus guidelines are crucial to guide oncologic management. Objective To develo…
View article: Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic Prostate Cancer
Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic Prostate Cancer Open
Importance Despite evidence demonstrating an overall survival benefit with up-front hormone therapy in addition to established synergy between hormone therapy and radiation, the addition of metastasis-directed therapy (MDT) to hormone ther…
View article: Supplemental Figures 1-6 and Supplemental Tables 1-3 from NQO1-Mediated Tumor-Selective Lethality and Radiosensitization for Head and Neck Cancer
Supplemental Figures 1-6 and Supplemental Tables 1-3 from NQO1-Mediated Tumor-Selective Lethality and Radiosensitization for Head and Neck Cancer Open
Supplemental Figure 1. Elevated NQO1 expression in patients with HNC correlates with poor overall survival to standard therapy; Supplemental Figure 2. Functional shRNA-NQO1 knockdown rescues β-lapinduced cell death; Supplemental Figure 3. …
View article: Supplemental Figures 1-6 and Supplemental Tables 1-3 from NQO1-Mediated Tumor-Selective Lethality and Radiosensitization for Head and Neck Cancer
Supplemental Figures 1-6 and Supplemental Tables 1-3 from NQO1-Mediated Tumor-Selective Lethality and Radiosensitization for Head and Neck Cancer Open
Supplemental Figure 1. Elevated NQO1 expression in patients with HNC correlates with poor overall survival to standard therapy; Supplemental Figure 2. Functional shRNA-NQO1 knockdown rescues β-lapinduced cell death; Supplemental Figure 3. …
View article: Supplemental Figure Legends from NQO1-Mediated Tumor-Selective Lethality and Radiosensitization for Head and Neck Cancer
Supplemental Figure Legends from NQO1-Mediated Tumor-Selective Lethality and Radiosensitization for Head and Neck Cancer Open
Supplemental Figure Legends; Supplemental Table Legends
View article: Data from NQO1-Mediated Tumor-Selective Lethality and Radiosensitization for Head and Neck Cancer
Data from NQO1-Mediated Tumor-Selective Lethality and Radiosensitization for Head and Neck Cancer Open
Ionizing radiation (IR) is a key therapeutic regimen for many head and neck cancers (HNC). However, the 5-year overall survival rate for locally advanced HNCs is approximately 50% and better therapeutic efficacy is needed. NAD(P)H:quinone …
View article: Data from NQO1-Mediated Tumor-Selective Lethality and Radiosensitization for Head and Neck Cancer
Data from NQO1-Mediated Tumor-Selective Lethality and Radiosensitization for Head and Neck Cancer Open
Ionizing radiation (IR) is a key therapeutic regimen for many head and neck cancers (HNC). However, the 5-year overall survival rate for locally advanced HNCs is approximately 50% and better therapeutic efficacy is needed. NAD(P)H:quinone …
View article: Supplemental Figure Legends from NQO1-Mediated Tumor-Selective Lethality and Radiosensitization for Head and Neck Cancer
Supplemental Figure Legends from NQO1-Mediated Tumor-Selective Lethality and Radiosensitization for Head and Neck Cancer Open
Supplemental Figure Legends; Supplemental Table Legends
View article: Optimizing Preventive Adjuvant Linac-Based (OPAL) Radiation: A Phase 2 Trial of Daily Partial Breast Irradiation
Optimizing Preventive Adjuvant Linac-Based (OPAL) Radiation: A Phase 2 Trial of Daily Partial Breast Irradiation Open
View article: Definitive Local Consolidative Therapy for Oligometastatic Solid Tumors: Results From the Lead-in Phase of the Randomized Basket Trial EXTEND
Definitive Local Consolidative Therapy for Oligometastatic Solid Tumors: Results From the Lead-in Phase of the Randomized Basket Trial EXTEND Open
View article: Alliance A082002 -a randomized phase II/III trial of modern immunotherapy-based systemic therapy with or without SBRT for PD-L1-negative, advanced non-small cell lung cancer
Alliance A082002 -a randomized phase II/III trial of modern immunotherapy-based systemic therapy with or without SBRT for PD-L1-negative, advanced non-small cell lung cancer Open
View article: Adoption of Ultrahypofractionated Radiation Therapy in Patients With Breast Cancer
Adoption of Ultrahypofractionated Radiation Therapy in Patients With Breast Cancer Open
View article: Optimizing Preventive Adjuvant LINAC (OPAL) Radiation: A Phase II Trial of Daily Partial Breast Irradiation
Optimizing Preventive Adjuvant LINAC (OPAL) Radiation: A Phase II Trial of Daily Partial Breast Irradiation Open
View article: American Radium Society Appropriate Use Criteria for Radiation Therapy in Oligometastatic or Oligoprogressive Non-Small Cell Lung Cancer
American Radium Society Appropriate Use Criteria for Radiation Therapy in Oligometastatic or Oligoprogressive Non-Small Cell Lung Cancer Open
View article: High-dose irradiation in combination with non-ablative low-dose radiation to treat metastatic disease after progression on immunotherapy: Results of a phase II trial
High-dose irradiation in combination with non-ablative low-dose radiation to treat metastatic disease after progression on immunotherapy: Results of a phase II trial Open