Stephen G. DeVries
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View article: Insulin-stimulated endoproteolytic TUG cleavage links energy expenditure with glucose uptake
Insulin-stimulated endoproteolytic TUG cleavage links energy expenditure with glucose uptake Open
View article: An insulin-stimulated proteolytic mechanism links energy expenditure with glucose uptake
An insulin-stimulated proteolytic mechanism links energy expenditure with glucose uptake Open
Summary Mechanisms to coordinately regulate energy expenditure and glucose uptake into muscle and fat cells are not well described. Insulin stimulates glucose uptake in part by causing site-specific endoproteolytic cleavage of TUG, which m…
View article: The Proximal Humeral Ossification System Improves Assessment of Maturity in Patients with Scoliosis
The Proximal Humeral Ossification System Improves Assessment of Maturity in Patients with Scoliosis Open
Background: We recently developed a classification system to assess skeletal maturity by scoring proximal humeral ossification in a similar way to the canonical Risser sign. The purpose of the present study was to determine whether our sys…
View article: Humeral Head Ossification Predicts Peak Height Velocity Timing and Percentage of Growth Remaining in Children
Humeral Head Ossification Predicts Peak Height Velocity Timing and Percentage of Growth Remaining in Children Open
Background: Understanding skeletal maturity is important in the management of idiopathic scoliosis. Iliac apophysis, triradiate cartilage, hand, and calcaneal ossification patterns have previously been described to assess both peak height …
View article: Usp25m protease regulates ubiquitin-like processing of TUG proteins to control GLUT4 glucose transporter translocation in adipocytes
Usp25m protease regulates ubiquitin-like processing of TUG proteins to control GLUT4 glucose transporter translocation in adipocytes Open
Insulin stimulates the exocytic translocation of specialized vesicles in adipocytes, which inserts GLUT4 glucose transporters into the plasma membrane to enhance glucose uptake. Previous results support a model in which TUG (Tether contain…