Stephen J. Libertini
YOU?
Author Swipe
View article: Alteration in expression and subcellular localization of the androgen receptor- regulated FAM111A protease is associated with emergence of castration resistant prostate cancer
Alteration in expression and subcellular localization of the androgen receptor- regulated FAM111A protease is associated with emergence of castration resistant prostate cancer Open
View article: Depletion of androgen receptor low molecular weight isoform reduces bladder tumor cell viability and induces apoptosis
Depletion of androgen receptor low molecular weight isoform reduces bladder tumor cell viability and induces apoptosis Open
View article: The p14ARF tumor suppressor restrains androgen receptor activity and prevents apoptosis in prostate cancer cells
The p14ARF tumor suppressor restrains androgen receptor activity and prevents apoptosis in prostate cancer cells Open
View article: XPO1 inhibition by selinexor induces potent cytotoxicity against high grade bladder malignancies
XPO1 inhibition by selinexor induces potent cytotoxicity against high grade bladder malignancies Open
Treatment options for high grade urothelial cancers are limited and have remained largely unchanged for several decades. Selinexor (KPT-330), a first in class small molecule that inhibits the nuclear export protein XPO1, has shown efficacy…
View article: A microbiome assessment of medical marijuana
A microbiome assessment of medical marijuana Open
View article: Dicer ablation promotes a mesenchymal and invasive phenotype in bladder cancer cells
Dicer ablation promotes a mesenchymal and invasive phenotype in bladder cancer cells Open
Dicer expression is frequently altered in cancer and affects a wide array of cellular functions acting as an oncogene or tumor suppressor in varying contexts. It has been shown that Dicer expression is also deregulated in urothelial cell c…
View article: miR-148a dependent apoptosis of bladder cancer cells is mediated in part by the epigenetic modifier DNMT1
miR-148a dependent apoptosis of bladder cancer cells is mediated in part by the epigenetic modifier DNMT1 Open
Urothelial cell carcinoma of the bladder (UCCB) is the most common form of bladder cancer and it is estimated that ~15,000 people in the United States succumbed to this disease in 2013. Bladder cancer treatment options are limited and rese…