Explanipedia

Effects of oral nicotine pouches on cigarette smoking behaviour and tobacco harm exposure: a randomised pilot trial in adults Open

Lisa M. Fucito, Stephen R. Baldassarri, Ran Wu, Ralitza Gueorguieva, Meghan E. Morean , et al. · 2025

Oral nicotine pouches may have potential for smoking cessation, but scientific evidence on the effects of pouches and their constituents on smoking behaviour is limited. Design This study was a 4-week, open-label, randomised pilot trial of…

Varenicline for E-Cigarette Cessation in Adults: A Preliminary Placebo-Controlled Randomized Trial Open

Lisa M. Fucito, Stephen R. Baldassarri, Nathaniel L. Baker, Amanda Palmer, Stephanie S. O’Malley , et al. · 2024

A new perspective on mitigating lung cancer risks through smoking cessation and reduction Open

Lisa M. Fucito, Amanda Palmer, Stephen R. Baldassarri · 2024

A randomized controlled trial of potential tobacco policies prohibiting menthol flavor in cigarettes and e-cigarettes: a study protocol Open

Krysten W. Bold, Akshika Sharma, Angela M. Haeny, Ralitza Gueorguieva, Eugenia Buta , et al. · 2024

Background Menthol cigarette use remains a large public health problem and disproportionately affects Black adults in the United States. The Food and Drug Administration has proposed prohibiting menthol flavor in cigarettes to protect publ…

Nicotine flux as a powerful tool for regulating nicotine delivery from e-cigarettes: Protocol of two complimentary randomized crossover clinical trials Open

Ahmad El‐Hellani, Elyana Hanna, Mehak Sharma, Reagan Blohowiak, Phillip Joseph , et al. · 2023

Introduction Electronic cigarette (EC) use has increased rapidly in the last decade, especially among youth. Regulating nicotine delivery from ECs could help curb youth uptake and leverage EC use in harm reduction yet is complicated by var…

Dog ownership may promote cardiometabolic health in U.S. military veterans Open

Steven H. Woodward, Stephen R. Baldassarri, Robert H. Pietrzak · 2023

0480 Psychoactive Substance Use and Sleep Characteristics Among Individuals with Untreated Obstructive Sleep Apnea Open

Alexander Walker, Stephen R. Baldassarri, J Chu, Annan Deng, Zhichao Xu , et al. · 2023

Introduction Obstructive sleep apnea (OSA) is characterized by recurrent airway obstruction causing intermittent hypoxia, arousal from sleep, and autonomic instability, and is associated with a variety of long-term health sequala. The frag…

Nicotine, alcohol, and caffeine use among individuals with untreated obstructive sleep apnea Open

Stephen R. Baldassarri, J Chu, Annan Deng, Zhichao Xu, Reagan Blohowiak , et al. · 2023

Morning Chronotype Is Associated with Improved Adherence to Continuous Positive Airway Pressure among Individuals with Obstructive Sleep Apnea Open

Melissa P. Knauert, Olurotimi Adekolu, Zhichao Xu, Annan Deng, J Chu , et al. · 2023

Rationale: Poor adherence limits the effectiveness of continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea (OSA). A better understanding of CPAP adherence is needed to develop novel strategies to improve it…

Receipt of Smoking Cessation Medications Among People With and Without Human Immunodeficiency Virus in the Veterans Aging Cohort Study (2003–2018) Open

Shahida Shahrir, Kristina Crothers, Kathleen A. McGinnis, Kwun Chuen Gary Chan, Jared M. Baeten , et al. · 2023

Background Nicotine replacement therapy, bupropion, and varenicline are smoking cessation medications (SCMs) shown to be similarly effective in people with and without human immunodeficiency virus (PWH and PWoH, respectively), although rat…

Cholinergic system adaptations are associated with cognitive function in people recently abstinent from smoking: a (-)-[18F]flubatine PET study Open

Katina C. Calakos, Ansel T. Hillmer, Jon Mikael Anderson, Brittany LeVasseur, Stephen R. Baldassarri , et al. · 2023

Nicotine Use and Metabotropic Glutamate Receptor 5 in Individuals With Major Depressive and Posttraumatic Stress Disorders Open

Stephen R. Baldassarri, Ruth Asch, Ansel T. Hillmer, Robert H. Pietrzak, Nicole DellaGioia , et al. · 2023

Metabotropic glutamate receptor 5 (mGluR5) dysregulation has been implicated in the pathophysiology of many psychiatric disorders, as well as nicotine use and dependence. We used positron emission tomography with [ 18 F]FPEB to measure mGl…

Dog Ownership May Promote Cardiac Health in U.S. Military Veterans: Results from the National Health and Resilience in Veterans Study Open

Steven H. Woodward, Stephen R. Baldassarri, Robert H. Pietrzak · 2022

Dog ownership has been associated with reduced cardiovascular and all-cause mortality in epidemiological samples. U.S. miliary Veterans exhibit elevated rates of cardiovascular disease. Associations between dog ownership and cardiovascular…

Recently Abstinent Smokers Exhibit Mood-Associated Dopamine Dysfunction in the Ventral Striatum Compared to Nonsmokers: A [11C]-(+)-PHNO PET Study Open

Katina C. Calakos, Ansel T. Hillmer, Gustavo A. Angarita, Stephen R. Baldassarri, Soheila Najafzadeh , et al. · 2021

Introduction Chronic nicotine exposure desensitizes dopamine responses in animals, but it is not known if this occurs in human tobacco smokers. Deficits in dopamine function are likely to make smoking cessation difficult. We used positron …

Lower synaptic density is associated with psychiatric and cognitive alterations in obesity Open

Ruth Asch, Sophie Holmes, Ania M. Jastreboff, Marc N. Potenza, Stephen R. Baldassarri , et al. · 2021

Use and perceptions of electronic nicotine delivery systems among patients attending lung cancer screening who smoke Open

Lisa M. Fucito, Krysten W. Bold, Stephen R. Baldassarri, John P. LaVigne, Bennie B. Ford , et al. · 2021

Lung Compliance Clusters of COVID-ARDS Identify Distinct Subgroups with Increased Mortality Open

S. Alapaty, Jonathan Siner, Maor Sauler, Stephen R. Baldassarri, J. Lucian Davis , et al. · 2021

INTRODUCTION: SARS-CoV-2 has been associated with high rates of severe hypoxemic respiratory failure. Severe COVID-19 is characterized by rapid development of acute respiratory distress syndrome (ARDS) requiring mechanical ventilation. ARD…

PET Imaging Estimates of Regional Acetylcholine Concentration Variation in Living Human Brain Open

Kelly Smart, Mika Naganawa, Stephen R. Baldassarri, Nabeel Nabulsi, Jim Ropchan , et al. · 2020

Acetylcholine (ACh) has distinct functional roles in striatum compared with cortex, and imbalance between these systems may contribute to neuropsychiatric disease. Preclinical studies indicate markedly higher ACh concentrations in the stri…

Clearing the Haze: What Do We Still Need to Learn about Electronic Nicotine Delivery Systems? Open

Lisa M. Fucito, Hannah Malinosky, Stephen R. Baldassarri, Roy S. Herbst · 2020

Electronic nicotine delivery systems (ENDS; i.e., electronic cigarettes, e-cigarettes, vaping devices, vape pens) were introduced to the U.S. market in 2007 as a potential harm reduction alternative for people who smoked combustible cigare…

Electronic Cigarettes Open

Stephen R. Baldassarri · 2020

Marijuana Vaping in U.S. Adults: Evidence From the Behavioral Risk Factor Surveillance System Open

Stephen R. Baldassarri, Deepa R. Camenga, David A. Fiellin, Abigail S. Friedman · 2020

Correlates of sleep quality and excessive daytime sleepiness in people with opioid use disorder receiving methadone treatment Open

Stephen R. Baldassarri, Mark Beitel, Andrey Zinchuk, Nancy S. Redeker, David E. Oberleitner , et al. · 2020

Inverse changes in raphe and cortical 5‐HT<sub>1B</sub> receptor availability after acute tryptophan depletion in healthy human subjects Open

Stephen R. Baldassarri, Eunkyung Park, Sjoerd J. Finnema, Beata Planeta, Nabeel Nabulsi , et al. · 2020

Serotonergic neurotransmission plays a key role in the pathophysiology and treatment of various neuropsychiatric diseases. The purpose of this study was to investigate changes in serotonergic neurotransmission after acute tryptophan deplet…

Receipt and predictors of smoking cessation pharmacotherapy among veterans with and without HIV Open

Shahida Shahrir, Kristina Crothers, Kathleen A. McGinnis, Kwun Chuen Gary Chan, Jared M. Baeten , et al. · 2020

Adapting Research Protocols in Response to E-Cigarette, or Vaping, Product Use Associated Lung Injury: A Response to CDC Recommendations for E-Cigarette Trials Open

Danielle R. Davis, Lisa M. Fucito, Grace Kong, Asti Jackson, Krysten W. Bold , et al. · 2020

The use of electronic cigarettes or e-cigarettes has grown in popularity over the last decade without extensive preclinical toxicology testing or long-term safety trials.1 In the e-cigarette marketplace, there are thousands of combinations…

Vaping—Seeking Clarity in a Time of Uncertainty Open

Stephen R. Baldassarri, David A. Fiellin, Abigail S. Friedman · 2019

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JA…

Nicotine dependence in US military veterans: results from the National Health and Resilience in Veterans Study Open

Stephen R. Baldassarri, Lorig K. Kachadourian, Irina Esterlis, Robert H. Pietrzak · 2019

Veterans with lifetime ND in the NHRVS survey were more likely to have psychiatric and medical conditions and lower physical functioning compared with Veterans without lifetime ND. Veterans with lifetime ND may therefore require a comprehe…

Electronic cigarette and tobacco use in individuals entering methadone or buprenorphine treatment Open

Stephen R. Baldassarri, David A. Fiellin, Mary Ellen Savage, Lynn M. Madden, Mark Beitel , et al. · 2019

Acknowledgment Open

Elizabeth L. Addington, Erica Ahlich, Carmela Alcántara, Melissa A. Alderfer, Julia Allan , et al. · 2019

Diagnosis of Infectious Diseases in the Lower Respiratory Tract: A Cytopathologist's Perspective Open

Rebecca Baldassarri, Deepika Kumar, Stephen R. Baldassarri, Guoping Cai · 2018

Context.— Respiratory cytology continues to play an important role in the diagnosis of lower respiratory tract infections. Prompt, accurate diagnosis of causative organisms is of paramount importance, particularly in immunosuppressed patie…

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