Stephen Sevalie
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View article: Impact of the COVID-19 pandemic on regional and national uptake of HIV testing services in Sierra Leone: a descriptive analysis
Impact of the COVID-19 pandemic on regional and national uptake of HIV testing services in Sierra Leone: a descriptive analysis Open
Our study shows that HIV testing was significantly disrupted during the COVID-19 pandemic but recovered quickly after the pandemic. These findings highlight that lessons learned from previous epidemics may influence adaptive strategies to …
View article: Effect of the COVID-19 pandemic on drug-resistant tuberculosis treatment outcomes at a national referral hospital in Sierra Leone, 2017 to 2022: a retrospective study
Effect of the COVID-19 pandemic on drug-resistant tuberculosis treatment outcomes at a national referral hospital in Sierra Leone, 2017 to 2022: a retrospective study Open
Introduction Sierra Leone is one of the 30 high TB burden countries, with an incidence rate in 2023 of 286 per 100,000 population. Despite progress in case notification and treatment coverage, around 5,000 cases of TB in Sierra Leone are m…
View article: Evidence of health-system resilience in the uptake of antiretroviral therapy in Sierra Leone during the COVID-19 pandemic: a nationwide retrospective study
Evidence of health-system resilience in the uptake of antiretroviral therapy in Sierra Leone during the COVID-19 pandemic: a nationwide retrospective study Open
Background Sustained access to and uptake of antiretroviral therapy (ART) among people living with HIV is a critical component of the HIV response. Limited data exist evaluating the extent to which the COVID-19 pandemic may have disrupted …
View article: Effect of the COVID-19 pandemic on the post-Ebola referral system in Sierra Leone: A descriptive analysis
Effect of the COVID-19 pandemic on the post-Ebola referral system in Sierra Leone: A descriptive analysis Open
Background The COVID-19 pandemic severely impacted health systems in several countries, including Sierra Leone, which was recovering from the 2014-2016 Ebola Virus Disease epidemic. The National Referral Service was established in 2017 fol…
View article: Stressors and coping strategies among people affected by Ebola Virus Disease (EVD) in West Africa: A qualitative study across multiple levels of the social ecology
Stressors and coping strategies among people affected by Ebola Virus Disease (EVD) in West Africa: A qualitative study across multiple levels of the social ecology Open
The 2014-16 Ebola Virus Disease (EVD) epidemic in West Africa is the most fatal on record and resulted in significant psychosocial and economic implications for those affected. Coping strategies and social supports can abate the effects of…
View article: Impact of Ebola and COVID-19 pandemic on patterns in uptake of short-acting and long-acting contraceptive methods in Sierra Leone: a country-wide observational study
Impact of Ebola and COVID-19 pandemic on patterns in uptake of short-acting and long-acting contraceptive methods in Sierra Leone: a country-wide observational study Open
Background The Ebola epidemic and COVID-19 pandemic disrupted essential healthcare services globally, including family planning, but the extent of disruptions in Sierra Leone is largely unknown. This study aimed to evaluates the impact of …
View article: Childhood Nutrition and Service Delivery Indicators across and between two Epidemics (Ebola and COVID-19) in Sierra Leone: A Descriptive Study using Serial Cross-Sectional Surveys
Childhood Nutrition and Service Delivery Indicators across and between two Epidemics (Ebola and COVID-19) in Sierra Leone: A Descriptive Study using Serial Cross-Sectional Surveys Open
Introduction Sierra Leone is one of the worst affected by hunger and food insecurity, but data to understand the impact of public health emergencies on nutrition indicators is limited. In this study, we sought to describe nutrition service…
View article: Evidence of Resiliency in Maternal Health Services and Outcomes in Kono District, Sierra Leone during the COVID-19 Pandemic: An Observational Study
Evidence of Resiliency in Maternal Health Services and Outcomes in Kono District, Sierra Leone during the COVID-19 Pandemic: An Observational Study Open
Background This study evaluated the resilience and outcomes of maternal health services during the COVID-19 pandemic in two health facilities in eastern Sierra Leone. Its aims to describe the use of maternal healthcare services and materna…
View article: Impact of the COVID-19 pandemic on regional and national uptake of HIV testing services in Sierra Leone: a descriptive analysis
Impact of the COVID-19 pandemic on regional and national uptake of HIV testing services in Sierra Leone: a descriptive analysis Open
Background A key milestone in the reduction of the global HIV burden is reaching the UNAIDS 95-95-95 target by 2025. The COVID-19 pandemic may have affected the ability of countries to achieve this target, but data to describe this impact …
View article: Impact of the COVID-19 pandemic on the uptake of intermittent sulphadoxine-pyrimethamine for prevention of malaria amongst pregnant women in Sierra Leone
Impact of the COVID-19 pandemic on the uptake of intermittent sulphadoxine-pyrimethamine for prevention of malaria amongst pregnant women in Sierra Leone Open
Background Malaria in pregnancy contributes to high maternal mortality, warranting the adoption of intermittent preventive treatment (IPTp) of malaria in pregnancy in Sierra Leone in 2017. Since then, the uptake of IPTp has increased but i…
View article: SARS‐CoV‐2 seroprevalence and associated factors among people living with HIV in Sierra Leone
SARS‐CoV‐2 seroprevalence and associated factors among people living with HIV in Sierra Leone Open
Background Human immunodeficiency virus (HIV) infection is an important risk factor for Coronavirus Disease 2019 (COVID‐19), but data on the prevalence of COVID‐19 among people living with HIV (PLWH) is limited in low‐income countries. Our…
View article: A qualitative study examining the health system’s response to COVID-19 in Sierra Leone
A qualitative study examining the health system’s response to COVID-19 in Sierra Leone Open
The paper examines the health system’s response to COVID-19 in Sierra Leone. It aims to explore how the pandemic affected service delivery, health workers, patient access to services, leadership, and governance. It also examines to what ex…
View article: Improving the quality of COVID-19 care in Sierra Leone: A modified Delphi process and serial nationwide assessments of quality of COVID-19 care in Sierra Leone
Improving the quality of COVID-19 care in Sierra Leone: A modified Delphi process and serial nationwide assessments of quality of COVID-19 care in Sierra Leone Open
Introduction Improving the quality of care that patients receive is paramount to improving patient outcomes and engendering trust during infectious disease outbreaks. Whilst Quality Improvement (QI) is well established to drive improvement…
View article: High incidence of catheter-associated urinary tract infections and related antibiotic resistance in two hospitals of different geographic regions of Sierra Leone: a prospective cohort study
High incidence of catheter-associated urinary tract infections and related antibiotic resistance in two hospitals of different geographic regions of Sierra Leone: a prospective cohort study Open
View article: Antibiotic use and consumption among medical patients of two hospitals in Sierra Leone: a descriptive report
Antibiotic use and consumption among medical patients of two hospitals in Sierra Leone: a descriptive report Open
Background Although one of the main drivers of antimicrobial resistance is inappropriate antibiotic prescribing, there are limited resources to support the surveillance of antibiotic consumption in low-income countries. In this study, we a…
View article: Have Hand Hygiene Practices in Two Tertiary Care Hospitals, Freetown, Sierra Leone, Improved in 2023 following Operational Research in 2021?
Have Hand Hygiene Practices in Two Tertiary Care Hospitals, Freetown, Sierra Leone, Improved in 2023 following Operational Research in 2021? Open
In 2021, an operational research study in two tertiary hospitals in Freetown showed poor hand hygiene compliance. Recommended actions were taken to improve the situation. Between February–April 2023, a cross-sectional study was conducted i…
View article: Ebola Virus Disease Sensitization: Community-Driven Efforts in Sierra Leone
Ebola Virus Disease Sensitization: Community-Driven Efforts in Sierra Leone Open
View article: Psychosocial impact of COVID-19 pandemic on front-line healthcare workers in Sierra Leone: an explorative qualitative study
Psychosocial impact of COVID-19 pandemic on front-line healthcare workers in Sierra Leone: an explorative qualitative study Open
Introduction The COVID-19 pandemic has wide-reaching health and non-health consequences, especially on mental health and psychosocial well-being. Healthcare workers involved in COVID-19 patient care are particularly vulnerable to psychosoc…
View article: Has Hand Hygiene Compliance in Two Tertiary Care Hospitals, Freetown, Sierra Leone, Improved in 2023 Following Operational Research in 2021?
Has Hand Hygiene Compliance in Two Tertiary Care Hospitals, Freetown, Sierra Leone, Improved in 2023 Following Operational Research in 2021? Open
In 2021, an operational research study in two tertiary hospitals, Freetown, showed poor hand hygiene compliance. Recommended actions were taken to improve the situation. Between February-April 2023, a cross-sectional study was conducted in…
View article: High incidence of catheter-associated urinary tract infections and related antibiotic resistance in two hospitals of different geographic regions of Sierra Leone: a prospective cohort study
High incidence of catheter-associated urinary tract infections and related antibiotic resistance in two hospitals of different geographic regions of Sierra Leone: a prospective cohort study Open
Objective Catheter-associated urinary tract infections (CAUTI) are common worldwide, but due to limited resources, its actual burden in low-income countries is unknown. Currently, there are gaps in knowledge about CAUTI due to lack of surv…
View article: All-cause mortality of hospitalised patients with suspected COVID-19 in Sierra Leone: a prospective cohort study
All-cause mortality of hospitalised patients with suspected COVID-19 in Sierra Leone: a prospective cohort study Open
Objectives To study the mortality of patients with COVID-19 in Sierra Leone, to explore the factors associated with mortality during the COVID-19 pandemic and to highlight the complexities of treating patients with a novel epidemic disease…
View article: Identification of Laboratory Biomarkers for Early Detection and Clinical Management of Post-Acute Syndrome Among Survivors of the 2013–2016 West Africa Ebola Outbreak in Sierra Leone
Identification of Laboratory Biomarkers for Early Detection and Clinical Management of Post-Acute Syndrome Among Survivors of the 2013–2016 West Africa Ebola Outbreak in Sierra Leone Open
We recommend clinicians closely monitor Hb, PCV, MCV, MCH, ALT, CREA, C-kinase, T-cholesterol, triglycerides and lymphocytes as clinically relevant laboratory biomarkers to identify survivors at higher risk of developing severe post-acute …
View article: The Barriers and Facilitators to Decentralised Nurse-Led Mental Health Service Delivery in Sierra Leone
The Barriers and Facilitators to Decentralised Nurse-Led Mental Health Service Delivery in Sierra Leone Open
In 2009, 98.0% of people with mental illness in Sierra Leone were not receiving treatment, partly due to the absence of public psychiatric facilities outside the capital. In response to this situation, the Ministry of Health and Sanitation…
View article: Social distancing, community stigma, and implications for psychological distress in the aftermath of Ebola virus disease
Social distancing, community stigma, and implications for psychological distress in the aftermath of Ebola virus disease Open
Background The 2013–2016 Ebola virus disease (EVD) epidemic resulted in more infections and deaths than all prior outbreaks in the 40-year history of this virus combined. This study examines how experiences of EVD infection, and preventive…
View article: Dysregulation of glutamine/glutamate metabolism in COVID‐19 patients: A metabolism study in African population and mini meta‐analysis
Dysregulation of glutamine/glutamate metabolism in COVID‐19 patients: A metabolism study in African population and mini meta‐analysis Open
Coronavirus disease 2019 (COVID‐19) remains a serious global threat. The metabolic analysis had been successfully applied in the efforts to uncover the pathological mechanisms and biomarkers of disease severity. Here we performed a quasi‐t…
View article: Comparison of the amount of SARS-CoV-2 exhaled by Delta and Omicron patients
Comparison of the amount of SARS-CoV-2 exhaled by Delta and Omicron patients Open
View article: Characteristics of SARS-CoV-2 exhaled by COVID-19 patients
Characteristics of SARS-CoV-2 exhaled by COVID-19 patients Open
View article: First Report of the Colistin Resistance Gene <i>mcr-10.1</i> Carried by Inc <sub>pA1763-KPC</sub> Plasmid pSL12517-mcr10.1 in Enterobacter cloacae in Sierra Leone
First Report of the Colistin Resistance Gene <i>mcr-10.1</i> Carried by Inc <sub>pA1763-KPC</sub> Plasmid pSL12517-mcr10.1 in Enterobacter cloacae in Sierra Leone Open
Colistin is used as one of the last available choices of antibiotics for patients infected by carbapenem-resistant bacterial strains, but the unrestricted use of colistin aggravated the acquisition and dissemination of mobile colistin resi…
View article: Hand Hygiene Compliance at Two Tertiary Hospitals in Freetown, Sierra Leone, in 2021: A Cross-Sectional Study
Hand Hygiene Compliance at Two Tertiary Hospitals in Freetown, Sierra Leone, in 2021: A Cross-Sectional Study Open
Hand hygiene actions are essential to reduce healthcare-associated infections and the development of antimicrobial resistance. In this cross-sectional study at two tertiary hospitals, Freetown, Sierra Leone, we observed hand hygiene compli…
View article: Incidence and risk factors of surgical site infections and related antibiotic resistance in Freetown, Sierra Leone: a prospective cohort study
Incidence and risk factors of surgical site infections and related antibiotic resistance in Freetown, Sierra Leone: a prospective cohort study Open