Salvatore V. Pizzo
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View article: SUN-663 Preclinical Evaluation of SYNT-101: Effects on Glycemic Control, Weight Loss, and Body Composition in DIO Rodents
SUN-663 Preclinical Evaluation of SYNT-101: Effects on Glycemic Control, Weight Loss, and Body Composition in DIO Rodents Open
Disclosure: M. Hudson: Syntis Bio. L. Sandoval: Syntis Bio. S. Pizzo: Syntis Bio. C. Dial: Syntis Bio. D. Sim: Syntis Bio. P.D. Susilo: Syntis Bio. F. Seta: None. R. Sharma: None. M. Lanchantin: Syntis Bio. S. Zale: None. G. Traverso: Synt…
View article: SUN-664 SYNT-101: First-in-Human Evaluation of a Novel Pharmacologic Therapeutic to Replicate Gastric Bypass for Management of Obesity
SUN-664 SYNT-101: First-in-Human Evaluation of a Novel Pharmacologic Therapeutic to Replicate Gastric Bypass for Management of Obesity Open
Disclosure: M. Hudson: Syntis Bio. L. Sandoval: Syntis Bio. P.D. Susilo: Syntis Bio. D. Sim: Syntis Bio. M. Buzo Pena: Syntis Bio. S. Pizzo: Syntis Bio. D. Ezekoye: None. A. Maheshwari: None. S. Cho: None. R. Sharma: None. M. Lanchantin: S…
View article: A porcine model of acute rejection for cardiac transplantation
A porcine model of acute rejection for cardiac transplantation Open
Ex vivo machine perfusion has been growing in utility for preserving donor organs prior to transplantation. This modality has tremendous potential for bioengineering and conditioning organs prior to transplantation using small molecule or …
View article: Supplemntary Figure 3 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Supplemntary Figure 3 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
Optimization of ascites treatment conditions
View article: Data from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Data from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
Patients with ovarian cancer are generally diagnosed at FIGO (International Federation of Gynecology and Obstetrics) stage III/IV, when ascites is common. The volume of ascites correlates positively with the extent of metastasis and negati…
View article: Supplementary Data from The Effects of Varying Dietary Carbohydrate and Fat Content on Survival in a Murine LNCaP Prostate Cancer Xenograft Model
Supplementary Data from The Effects of Varying Dietary Carbohydrate and Fat Content on Survival in a Murine LNCaP Prostate Cancer Xenograft Model Open
Supplementary Data from The Effects of Varying Dietary Carbohydrate and Fat Content on Survival in a Murine LNCaP Prostate Cancer Xenograft Model
View article: Supplementary Data from The Effects of Varying Dietary Carbohydrate and Fat Content on Survival in a Murine LNCaP Prostate Cancer Xenograft Model
Supplementary Data from The Effects of Varying Dietary Carbohydrate and Fat Content on Survival in a Murine LNCaP Prostate Cancer Xenograft Model Open
Supplementary Data from The Effects of Varying Dietary Carbohydrate and Fat Content on Survival in a Murine LNCaP Prostate Cancer Xenograft Model
View article: Supplementary Figure 4 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Supplementary Figure 4 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
MemGRP78 positive tumor cells have a lower proliferation rate
View article: Supplementary Figure 1 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Supplementary Figure 1 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
Characterization of ID8 cell line
View article: Supplementary Table 2 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Supplementary Table 2 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
Stemness genes
View article: Supplementary Table 1 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Supplementary Table 1 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
Selected genes
View article: Supplementary Figure 4 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Supplementary Figure 4 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
MemGRP78 positive tumor cells have a lower proliferation rate
View article: Data from The Effects of Varying Dietary Carbohydrate and Fat Content on Survival in a Murine LNCaP Prostate Cancer Xenograft Model
Data from The Effects of Varying Dietary Carbohydrate and Fat Content on Survival in a Murine LNCaP Prostate Cancer Xenograft Model Open
Purpose: Numerous dietary factors elevate serum levels of insulin and insulin-like growth factor I (IGF-I), both potent prostate cancer mitogens. We tested whether varying dietary carbohydrate and fat, without energy restriction relative t…
View article: Supplementary Figure 2 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Supplementary Figure 2 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
Ascites from ovarian cancer-bearing mice contributes to a faster progression of the cancer.
View article: Supplementary Figure Legends from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Supplementary Figure Legends from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
Supplementary Figure Legends
View article: Supplementary Figure 1 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Supplementary Figure 1 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
Characterization of ID8 cell line
View article: Data from The Effects of Varying Dietary Carbohydrate and Fat Content on Survival in a Murine LNCaP Prostate Cancer Xenograft Model
Data from The Effects of Varying Dietary Carbohydrate and Fat Content on Survival in a Murine LNCaP Prostate Cancer Xenograft Model Open
Purpose: Numerous dietary factors elevate serum levels of insulin and insulin-like growth factor I (IGF-I), both potent prostate cancer mitogens. We tested whether varying dietary carbohydrate and fat, without energy restriction relative t…
View article: Supplementary Figure Legends from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Supplementary Figure Legends from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
Supplementary Figure Legends
View article: Supplementary Figure 2 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Supplementary Figure 2 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
Ascites from ovarian cancer-bearing mice contributes to a faster progression of the cancer.
View article: Supplementary Figure 5 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Supplementary Figure 5 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
MemGRP78 positive tumor cells have a lower proliferation rate
View article: Data from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Data from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
Patients with ovarian cancer are generally diagnosed at FIGO (International Federation of Gynecology and Obstetrics) stage III/IV, when ascites is common. The volume of ascites correlates positively with the extent of metastasis and negati…
View article: Supplementary Figure 5 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Supplementary Figure 5 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
MemGRP78 positive tumor cells have a lower proliferation rate
View article: Supplemntary Figure 3 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Supplemntary Figure 3 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
Optimization of ascites treatment conditions
View article: Supplementary Table 2 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Supplementary Table 2 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
Stemness genes
View article: Supplementary Table 1 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78
Supplementary Table 1 from Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78 Open
Selected genes
View article: An antibody that targets cell‐surface glucose‐regulated protein‐78 inhibits expression of inflammatory cytokines and plasminogen activator inhibitors by macrophages
An antibody that targets cell‐surface glucose‐regulated protein‐78 inhibits expression of inflammatory cytokines and plasminogen activator inhibitors by macrophages Open
Glucose‐regulated protein‐78 (Grp78) is an endoplasmic reticulum chaperone, which is secreted by cells and associates with cell surfaces, where it functions as a receptor for activated α 2 ‐macroglobulin (α 2 M) and tissue‐type plasminogen…
View article: Serum Pro‐N‐Cadherin Is a Marker of Subclinical Heart Failure in the General Population
Serum Pro‐N‐Cadherin Is a Marker of Subclinical Heart Failure in the General Population Open
Background We recently reported aberrant processing and localization of the precursor PNC (pro‐N‐cadherin) protein in failing heart tissues and detected elevated PNC products in the plasma of patients with heart failure. We hypothesize tha…
View article: Physiological Roles of the Autoantibodies to the 78-Kilodalton Glucose-Regulated Protein (GRP78) in Cancer and Autoimmune Diseases
Physiological Roles of the Autoantibodies to the 78-Kilodalton Glucose-Regulated Protein (GRP78) in Cancer and Autoimmune Diseases Open
The 78 kDa glucose-regulated protein (GRP78), a member of the 70 kDa heat-shock family of molecular chaperones (HSP70), is essential for the regulation of the unfolded protein response (UPR) resulting from cellular endoplasmic reticulum (E…