Steve Orme
YOU?
Author Swipe
View article: Time to first remission and survival in patients with acromegaly: Evidence from the UK Acromegaly Register Study (UKAR)
Time to first remission and survival in patients with acromegaly: Evidence from the UK Acromegaly Register Study (UKAR) Open
Objective This study aimed to understand the effect of time to remission of acromegaly on survival in people living with acromegaly. Design, Patients and Measurement This cross‐sectional study used data from the UK Acromegaly Register. We …
View article: Increased mortality in acromegaly is due to vascular and respiratory disease and is normalised by control of GH levels—A retrospective analysis from the UK Acromegaly Register 1970–2016
Increased mortality in acromegaly is due to vascular and respiratory disease and is normalised by control of GH levels—A retrospective analysis from the UK Acromegaly Register 1970–2016 Open
Context Epidemiological studies involving patients with acromegaly have yielded conflicting results regarding cancer incidence and causes of mortality in relation to control of growth hormone (GH) excess. Objective The objective of this re…
View article: Post-operative volumes following endoscopic surgery for non-functioning pituitary macroadenomas are predictive of further intervention, but not endocrine outcomes
Post-operative volumes following endoscopic surgery for non-functioning pituitary macroadenomas are predictive of further intervention, but not endocrine outcomes Open
Background Transsphenoidal surgery (TSS) remains the treatment of choice for non-functioning pituitary macroadenomas (NFPMA). The value of measuring tumour volumes before and after surgery, and its influence on endocrine outcomes and furth…
View article: Prothrombotic fibrin network characteristics in patients with acromegaly: a novel mechanism for vascular complications
Prothrombotic fibrin network characteristics in patients with acromegaly: a novel mechanism for vascular complications Open
Objective There remains increased cardiovascular mortality in patients with acromegaly. This study aims to evaluate whether GH/IGF-1 excess increases vascular disease by adversely affecting fibrin network characteristics. Design Cross-sect…