Steven Ades
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View article: Venous thromboembolism in patients with pancreatic adenocarcinoma: Disease burden and initiation of ambulatory thromboprophylaxis
Venous thromboembolism in patients with pancreatic adenocarcinoma: Disease burden and initiation of ambulatory thromboprophylaxis Open
VTE risk is significant and morbid in PAC patients. AT rates are low, and initiation is often delayed. Therapeutic endoscopists diagnosing PAC may be helpful in AT initiation.
View article: PB0940 Guideline Implementation Successes and Barriers to Prevent Cancer Associated Thrombosis in Community and Rural Cancer Clinics
PB0940 Guideline Implementation Successes and Barriers to Prevent Cancer Associated Thrombosis in Community and Rural Cancer Clinics Open
Background: Intensification of asparaginase treatment in pediatric-inspired chemotherapy regimens for adults with acute lymphoblastic leukemia (ALL) has improved survival, but also increased venous thromboembolism (VTE) risk with incidence…
View article: A phase <scp>II</scp> study of alternating sunitinib and temsirolimus therapy in patients with metastatic renal cell carcinoma
A phase <span>II</span> study of alternating sunitinib and temsirolimus therapy in patients with metastatic renal cell carcinoma Open
Background Sunitinib is a multi‐target tyrosine kinase inhibitor (TKI) that inhibits VEGF receptor 1, 2, 3 (VEGFRs), platelet‐derived growth factor receptor (PDGFR), colony‐stimulating factor receptor (CSFR), and the stem cell factor recep…
View article: ‘CROSS’-ing into the ‘Real World’: a retrospective cohort study of patients receiving trimodality and bimodality therapy for esophageal cancer
‘CROSS’-ing into the ‘Real World’: a retrospective cohort study of patients receiving trimodality and bimodality therapy for esophageal cancer Open
Patients receiving trimodality therapy were observed to have superior overall survival compared to bimodality therapy. Patient preference for organ-preserving therapies appears to impact resection rate; further characterization of patient …
View article: Risk factors for venous thromboembolism in metastatic colorectal cancer with contemporary treatment: A <scp>SEER‐Medicare</scp> analysis
Risk factors for venous thromboembolism in metastatic colorectal cancer with contemporary treatment: A <span>SEER‐Medicare</span> analysis Open
Background The relationship between metastatic colorectal cancer (mCRC) and venous thromboembolism (VTE) is poorly defined in the modern era. Our objective was to examine impact of putative risk factors including newer treatments and anti‐…
View article: Cost-effectiveness of Prostate Radiation Therapy for Men With Newly Diagnosed Low-Burden Metastatic Prostate Cancer
Cost-effectiveness of Prostate Radiation Therapy for Men With Newly Diagnosed Low-Burden Metastatic Prostate Cancer Open
In the economic evaluation, PRT was a dominant treatment strategy compared with ADT alone. These findings suggest that addition of PRT to ADT is a cost-effective treatment for men with low-volume mHSPC.
View article: Nivolumab-Induced Thrombotic Thrombocytopenic Purpura in a Patient with Anal Squamous Cell Carcinoma: A Lesson on Hematologic Toxicity from Immunotherapy
Nivolumab-Induced Thrombotic Thrombocytopenic Purpura in a Patient with Anal Squamous Cell Carcinoma: A Lesson on Hematologic Toxicity from Immunotherapy Open
Thrombotic thrombocytopenic purpura (TTP) is a rare but life-threatening microangiopathic hemolytic anemia characterized by thrombocytopenia, hemolytic anemia, and ischemic organ damage. It is mainly caused by an autoreactive antibody dire…
View article: Successful Model for Guideline Implementation to Prevent Cancer-Associated Thrombosis: Venous Thromboembolism Prevention in the Ambulatory Cancer Clinic
Successful Model for Guideline Implementation to Prevent Cancer-Associated Thrombosis: Venous Thromboembolism Prevention in the Ambulatory Cancer Clinic Open
PURPOSE: Guidelines recommend venous thromboembolism (VTE) risk assessment in outpatients with cancer and pharmacologic thromboprophylaxis in selected patients at high risk for VTE. Although validated risk stratification tools are availabl…
View article: Nanoparticle‐based targeted cancer strategies for non‐invasive prostate cancer intervention
Nanoparticle‐based targeted cancer strategies for non‐invasive prostate cancer intervention Open
Prostate cancer is screened by testing circulating levels of the prostate‐specific antigen (PSA) biomarker, monitoring changes over time, or a digital rectal exam. Abnormal results often lead to prostate biopsy. Prostate cancer positive pa…