Steven Arora
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View article: Practice Variation in the Use of Steroid-sparing Therapies in Childhood Steroid Sensitive Nephrotic Syndrome: Results from a Prospective Cohort Study
Practice Variation in the Use of Steroid-sparing Therapies in Childhood Steroid Sensitive Nephrotic Syndrome: Results from a Prospective Cohort Study Open
Background Steroid-sparing therapies are often used to prolong disease remission while minimizing steroid toxicity in childhood steroid-sensitive nephrotic syndrome (SSNS). This study aims to describe practice variation in the use of stero…
View article: Identification of a Locus on the X Chromosome Linked to Familial Membranous Nephropathy
Identification of a Locus on the X Chromosome Linked to Familial Membranous Nephropathy Open
View article: Anterior Ischemic Optic Neuropathy in a Child Receiving Chronic Hemodialysis
Anterior Ischemic Optic Neuropathy in a Child Receiving Chronic Hemodialysis Open
Anterior ischemic optic neuropathy (AION) occurs due to hypoperfusion of the optic nerve and is a rare complication in patients receiving maintenance dialysis. To date, AION has only been reported in 22 children, all of whom were receiving…
View article: Management of Pediatric Kidney Transplant Patients During the COVID-19 Pandemic: Guidance From the Canadian Society of Transplantation Pediatric Group
Management of Pediatric Kidney Transplant Patients During the COVID-19 Pandemic: Guidance From the Canadian Society of Transplantation Pediatric Group Open
Purpose of the program: To provide guidance on the management of pediatric kidney transplant patients during the COVID-19 pandemic. Sources of information: Program-specific documents, preexisting, and related to COVID-19; documents from pr…
View article: Long-term Eculizumab Therapy in a Child With Refractory Immune Complex–Mediated Membranoproliferative Glomerulonephritis
Long-term Eculizumab Therapy in a Child With Refractory Immune Complex–Mediated Membranoproliferative Glomerulonephritis Open
There have been recent developments in the understanding of the pathogenesis of membranoproliferative glomerulonephritis (MPGN) supporting a prominent role for the complement alternative pathway (AP).1,2 MPGN due to AP dysregulation has be…
View article: Setting New Directions for Research in Childhood Nephrotic Syndrome: Results From a National Workshop
Setting New Directions for Research in Childhood Nephrotic Syndrome: Results From a National Workshop Open
Background: We report on the proceedings of a national workshop held in Canada with the aims to identify priorities for research in childhood nephrotic syndrome and to develop a national strategy to address these priorities. Methods: A div…
View article: Perceptions of Pediatric Nephrologists regarding Timing of Dialysis Initiation in Children in Canada
Perceptions of Pediatric Nephrologists regarding Timing of Dialysis Initiation in Children in Canada Open
Background: Significant practice variation exists in Canada with respect to timing of dialysis initiation in children. In the absence of evidence to guide practice, physicians' perceptions may significantly influence decision-making. Objec…
View article: Steroid Retrial After Rituximab and Mycophenolate Mofetil in Pediatric Refractory Nephrotic Syndrome
Steroid Retrial After Rituximab and Mycophenolate Mofetil in Pediatric Refractory Nephrotic Syndrome Open
Steroid-resistant nephrotic syndrome (SRNS) is a challenging condition. In pediatric SRNS, cyclosporine is the first-line treatment choice, with approximately 60% success rate. In cyclosporine-resistant disease, treatment modalities such a…