Explanipedia

Global Results From the Optimize PRO Study: Standardized TAVR Technique and Care Pathway Open

Kendra J. Grubb, Hemal Gada, Douglas Fraser, Josep Rodés‐Cabau, Tamim Nazif , et al. · 2025

Sealing the Leak: Transcatheter Repair of Anterior Mitral Leaflet Perforation With Amplatzer Vascular Plug 4 Open

Zeryab Khan, Cody Carter, Jordan Luli, Nathan Marzlin, Johnathan Hatanelas , et al. · 2025

Three-Year Outcomes Following TAVR in Younger (<75 Years) Low-Surgical-Risk Severe Aortic Stenosis Patients Open

Thomas Modine, Didier Tchétché, Nicolas M. Van Mieghem, G. Michael Deeb, Stanley Chetcuti , et al. · 2024

BACKGROUND: Transcatheter aortic valve replacement (TAVR) is an alternative to surgery in patients with severe aortic stenosis, but data are limited on younger, low-risk patients. This analysis compares outcomes in low-surgical-risk patien…

OR3-6 | Early Outcomes from the Optimize PRO TAVR Care Pathway Evolut FX System Addendum Study Open

Hemal Gada, Steven J. Yakubov, Ramzi F. Khalil, Stanley Chetcuti, G. Michael Deeb , et al. · 2024

The Optimize PRO study interim analysis reported favorable outcomes using a TAVR "optimized" care pathway and cusp overlap technique (COT) resulting in low permanent pacemaker implantation rates and no moderate or severe aortic regurgitati…

Pulmonary Vein Isolation With or Without Left Atrial Appendage Ligation in Atrial Fibrillation Open

Dhanunjaya Lakkireddy, David J. Wilber, Suneet Mittal, David Tschopp, Christopher R. Ellis , et al. · 2024

Importance Left atrial appendage elimination may improve catheter ablation outcomes for atrial fibrillation. Objective To assess the safety and effectiveness of percutaneous left atrial appendage ligation adjunctive to catheter pulmonary v…

Simplifying Transcatheter Tricuspid Valve Replacement With 3-Dimensional Intracardiac Echocardiography Open

Carlos E. Sanchez, Steven J. Yakubov · 2024

Redo-TAVI with the ACURATE neo2 and Prime XL for balloon-expandable transcatheter heart valve failure Open

David Meier, Daire Grant, Chris Frawley, Mariama Akodad, Uri Landes , et al. · 2024

Redo-TAVI with an ACn2/AC XL within an S3 has favourable hydrodynamic performance and less pinwheeling compared to an S3 in S3. This comes at the price of a taller neoskirt.

Transcatheter Aortic Valve Replacement in Discordant Aortic Stenosis: The Time Is Now Open

Vikrant Jagadeesan, Carlos E. Sanchez, Steven J. Yakubov · 2024

Management of Postprocedural Conduction Disturbances Using a Prespecified Algorithm in the Optimize PRO Study Open

Kendra J. Grubb, Steven J. Yakubov, Tamim Nazif, Suneet Mittal, Hemal Gada , et al. · 2023

Effective management of CDs using a standard algorithm following Evolut TAVR provides similar 30-day safety outcomes to patients without CDs who undergo routine next day discharge. The CD algorithm may provide an effective strategy to reco…

3-Year Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis Open

John K. Forrest, G. Michael Deeb, Steven J. Yakubov, Hemal Gada, Mubashir Mumtaz , et al. · 2023

Within the Evolut Low Risk study, TAVR at 3 years showed durable benefits compared with surgery with respect to all-cause mortality or disabling stroke. (Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk Patients; NCT0270…

Clinical Impact of Standardized TAVR Technique and Care Pathway Open

Kendra J. Grubb, Hemal Gada, Suneet Mittal, Tamim Nazif, Josep Rodés‐Cabau , et al. · 2023

The use of the TAVR care pathway and COT resulted in favorable clinical outcomes with no moderate or severe AR and low PPI rates at 30 days while facilitating early discharge and reproducible outcomes across various sites and operators. (O…

Volumetric Intracardiac Echocardiogram-Guided MitraClip in Patients Intolerant to Transesophageal Echocardiogram: Results From a Multicenter Registry Open

Tai Pham, Jade Tso, Carlos E. Sanchez, Steven J. Yakubov, Edris Aman , et al. · 2023

Structural Valve Deterioration After Self-Expanding Transcatheter or Surgical Aortic Valve Implantation in Patients at Intermediate or High Risk Open

Daniel O’Hair, Steven J. Yakubov, Kendra J. Grubb, Jae K. Oh, Saki Ito , et al. · 2022

Importance The frequency and clinical importance of structural valve deterioration (SVD) in patients undergoing self-expanding transcatheter aortic valve implantation (TAVI) or surgery is poorly understood. Objective To evaluate the 5-year…

Propensity-Matched Outcomes Comparing TAVR in Bicuspid vs Surgery in Tricuspid Aortic Valve Stenosis Open

G. Michael Deeb, Steven J. Yakubov, Michael J. Reardon, Basel Ramlawi, Stan Chetcuti , et al. · 2022

In this select group of low-risk bicuspid patients, in the short-term follow-up, TAVR appears to have similar outcomes to those seen in comparable low-risk tricuspid patients undergoing SAVR.

Self-expanding Transcatheter vs Surgical Aortic Valve Replacement in Intermediate-Risk Patients Open

Nicolas M. Van Mieghem, G. Michael Deeb, Lars Søndergaard, Eberhard Grube, Stephan Windecker , et al. · 2022

Importance In patients with severe aortic valve stenosis at intermediate surgical risk, transcatheter aortic valve replacement (TAVR) with a self-expanding supra-annular valve was noninferior to surgery for all-cause mortality or disabling…

Functional Status After Transcatheter and Surgical Aortic Valve Replacement Open

Mark Tuttle, Bob Kiaii, Nicolas M. Van Mieghem, Roger J. Laham, G. Michael Deeb , et al. · 2022

SCAI Position Statement on Best Practices for Clinical Proctoring of New Technologies and Techniques Open

Arnold H. Seto, Peter L. Duffy, Creighton W. Don, Prashant Kaul, Anbukarasi Maran , et al. · 2022

Incidence and Outcomes of Infective Endocarditis After Transcatheter or Surgical Aortic Valve Replacement Open

Jonas Lanz, Michael J. Reardon, Thomas Pilgrim, Stefan Stortecky, G. Michael Deeb , et al. · 2021

Background Data comparing the frequency and outcomes of infective endocarditis (IE) after transcatheter (TAVR) to surgical aortic valve replacement (SAVR) are scarce. The objective of this study is to compare the incidence and outcomes of …

Transcatheter Aortic Valve Replacement With Self‐Expandable Supra‐Annular Valves for Degenerated Surgical Bioprostheses: Insights From Transcatheter Valve Therapy Registry Open

Luís Augusto Palma Dallan, John K. Forrest, Michael J. Reardon, Wilson Y. Szeto, Isaac George , et al. · 2021

Background Transcatheter aortic valve replacement with supra‐annular transcatheter heart valves has been adopted in patients with degenerated surgical aortic valves. The next generation self‐expanding Evolut PRO valve has not been evaluate…

Hot topics in interventional cardiology: Proceedings from the society for cardiovascular angiography and interventions (SCAI) 2021 think tank Open

Srihari S. Naidu, Suzanne J. Baron, Marvin H. Eng, Shyam Sathanandam, David A. Zidar , et al. · 2021

The Society for Cardiovascular Angiography and Interventions (SCAI) Think Tank is a collaborative venture that brings together interventional cardiologists, administrative partners, and select members of the cardiovascular industry communi…

Five-Year Clinical and Quality of Life Outcomes From the CoreValve US Pivotal Extreme Risk Trial Open

Suzanne V. Arnold, George Petrossian, Michael J. Reardon, Neal S. Kleiman, Steven J. Yakubov , et al. · 2021

Background: Older adults with comorbidities who are at extreme risk for surgical aortic valve replacement may be appropriate candidates for transcatheter aortic valve replacement (TAVR). We present the 5-year clinical, echocardiographic, a…

1-Year Outcomes following Bioprosthetic Valve Fracture to Facilitate Valve-in-Valve Transcatheter Aortic Valve Replacement Open

Adnan K. Chhatriwalla, Keith B. Allen, John Saxon, David J. Cohen, Tom C. Nguyen , et al. · 2021

BackgroundBioprosthetic valve fracture (BVF) improves the hemodynamic results of valve-in-valve transcatheter aortic valve replacement (VIV TAVR) by facilitating optimal expansion of the transcatheter heart valve (THV). Long-term outcomes …

Infective endocarditis after transcatheter or surgical aortic valve implantation: pooled results from three randomized controlled trials Open

Jonas Lanz, Jeffrey J. Popma, Michael J. Reardon, Thomas Pilgrim, Stefan Stortecky , et al. · 2020

Background Infective endocarditis is a rare complication of aortic valve replacement with high morbidity and mortality. Data of randomized trials comparing the incidence and outcomes between surgical (SAVR) and transcatheter aortic valve r…

Overcoming the transcatheter aortic valve replacement Achilles heel: coronary re-access Open

Arash Arshi, Steven J. Yakubov, Kevin Stiver, Carlos E. Sanchez · 2020

Transcatheter aortic valve replacement (TAVR) is an alternative to surgical aortic valve replacement (SAVR) for the treatment of symptomatic severe aortic stenosis (AS). Coronary artery disease (CAD) is common in patients with severe AS. A…

Five-Year Health Status After Self-expanding Transcatheter or Surgical Aortic Valve Replacement in High-risk Patients With Severe Aortic Stenosis Open

Suzanne V. Arnold, Khaja Chinnakondepalli, Elizabeth A. Magnuson, Michael J. Reardon, G. Michael Deeb , et al. · 2020

ClinicalTrials.gov Identifier: NCT01240902.

Computed Tomography Annular Dimensions: A Novel Method to Compare Prosthetic Valve Hemodynamics Open

G. Michael Deeb, Jeffrey J. Popma, Stanley Chetcuti, Steven J. Yakubov, Mubashir Mumtaz , et al. · 2020

Durability and Clinical Outcomes of Transcatheter Aortic Valve Replacement for Failed Surgical Bioprostheses Open

Harold L. Dauerman, G. Michael Deeb, Daniel O’Hair, Ron Waksman, Steven J. Yakubov , et al. · 2019

Background: Valve-in-valve transcatheter aortic valve replacement (TAVR) is an option when a surgical valve demonstrates deterioration and dysfunction. This study reports 3-year results following valve-in-valve with self-expanding TAVR. Me…

Comparison of a Complete Percutaneous Versus Surgical Approach to Aortic Valve Replacement and Revascularization in Patients at Intermediate Surgical Risk Open

Lars Søndergaard, Jeffrey J. Popma, Michael J. Reardon, Nicolas M. Van Mieghem, G. Michael Deeb , et al. · 2019

Background: For patients with severe aortic stenosis and coronary artery disease, the completely percutaneous approach to aortic valve replacement and revascularization has not been compared with the standard surgical approach. Methods: Th…

The initial U.S. experience with the Tempo active fixation temporary pacing lead in structural heart interventions Open

Tamim Nazif, Shmuel Chen, Pablo Codner, Paul Grossman, Daniel Menees , et al. · 2019

Objectives This multicenter retrospective study of the initial U.S. experience evaluated the safety and efficacy of temporary cardiac pacing with the Tempo® Temporary Pacing Lead. Background Despite increasing use of temporary cardiac paci…

Comparison of Outcomes After Transcatheter vs Surgical Aortic Valve Replacement Among Patients at Intermediate Operative Risk With a History of Coronary Artery Bypass Graft Surgery Open

Michael J. Reardon, Robin H. Heijmen, Nicolas M. Van Mieghem, Mathew Williams, Steven J. Yakubov , et al. · 2019

IMPORTANCE: Surgical aortic valve replacement (SAVR) has increased risk for patients with aortic stenosis (AS) and a history of coronary artery bypass graft (CABG) surgery. Transcatheter aortic valve replacement (TAVR) may be an alternativ…

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