Explanipedia

Impact of Systemic Therapy for Renal Cell Carcinoma With a Tumor Thrombus: Results From the Intercontinental Collaboration on Renal Cell Carcinoma Database Open

Maxwell Sandberg, Gregory B. Russell, Dana Feldman, Mitchell Hayes, Reuben Ben‐David , et al. · 2025

There appears to be an OS and CSS benefit to preoperative systemic therapy for mRCC-TT. Further analysis is required to elucidate the best therapy regimens and ideal timing.

Intraoperative Frozen Section Analysis (IFSA): One Plastic Surgeon’s Experience with 1598 Consecutive Skin Cancer Removals Open

Lawrence Chang, Michael Chang, Steven L. Chang, Matthew M. Delancy, James Monihan , et al. · 2025

Longitudinal analysis of postoperative symptom clusters in patients undergoing esophageal cancer surgery Open

Steven L. Chang, Xiaolong Wang, Yuqin Cao, Hecheng Li, Yanxia Hu · 2025

Postoperative EC patients experience multiple symptom clusters, with some clusters persisting over time. The composition and severity of these clusters vary across different longitudinal time points. Healthcare providers should closely mon…

A comparison of renal cell carcinoma with tumor thrombus across North America, Central/South America, and South Korea Open

Maxwell Sandberg, Rachel Vancavage, Claudia Marie‐Costa, Emily Ye, Mitchell Hayes , et al. · 2025

Purpose: With multi-institutional collaboration, the purpose of this study was to analyze geographical differences of renal cell carcinoma with tumor thrombus between patients in North America, Central/South America, and South Korea. Mater…

Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma Open

Kevin Bi, Meng Xiao He, Ziad Bakouny, Abhay Kanodia, Sara Napolitano , et al. · 2025

Frozen Section Mohs Open

Michael Chang, Steven L. Chang, Fady Gerges, Matthew M. Delancy, Aoxue Yang , et al. · 2025

While US nonmelanoma skin cancer (NMSC) mortality rate has decreased in the past decade, its incidence is rising. Traditional surgical treatments include wide local excision, intraoperative frozen section analysis (IFSA), and Mohs microgra…

A neoantigen vaccine generates antitumour immunity in renal cell carcinoma Open

David A. Braun, Giorgia Moranzoni, Vipheaviny Chea, Bradley A. McGregor, Eryn Blass , et al. · 2025

29 Pilot study of an implantable microdevice for<i>in vivo</i> evaluation of drug response in renal cell carcinoma (NCT05700461) Open

Wenxin Xu, Sharath K. Bhagavatula, Clara Steiner, Caiwei Zhong, Matthew Mossanen , et al. · 2024

Background There are multiple therapies for renal cell carcinoma (RCC), yet no personalized biomarkers exist that can guide optimal treatment for individual patients. We developed implantable microdevices (IMD) that can be placed within a …

Protective role for kidney TREM2 macrophages in obesity- and diabetes-induced kidney injury Open

Ayshwarya Subramanian, Katherine A. Vernon, Yiming Zhou, Jamie L. Marshall, Maria Alimova , et al. · 2024

Impact of smoking status on health-related quality of life (HRQoL) in cancer survivors Open

José Ignacio Nolazco, Bernard Rosner, Emily Roebuck, Cristiane Decat Bergerot, Elke Rammant , et al. · 2024

Introduction The Health-Related Quality of Life (HRQoL) often declines among cancer survivors due to many factors. Some cancer patients who smoke before the cancer diagnosis continue this harmful habit, potentially contributing to a more s…

Navigating the labyrinth: A comprehensive approach to managing renal masses in young patients Open

Diego Moreira Capibaribe, José Ignacio Nolazco, Steven L. Chang, Leonardo Oliveira Reis · 2024

Facilitating RP2D decisions for CAR T cell therapy clinical studies using a QSP model Open

Alexander V. Ratushny, Christopher Anderson, Akintunde Bello, Steven L. Chang, Yanping Chen , et al. · 2024

Urological impact of race-free estimated glomerular filtration rate equations Open

Natália Dalsenter Avilez, José Ignacio Nolazco, Steven L. Chang, Leonardo Oliveira Reis · 2023

Smoking status among cancer patients by medical specialty: A U.S. nationwide representative analysis Open

José Ignacio Nolazco, Yuzhe Tang, Khalid Y. Alkhatib, Andrew J. King, Matthew Mossanen , et al. · 2023

Background Persistence in tobacco use among cancer survivors has been associated with a multitude of clinicodemographic factors. However, there is a paucity of understanding regarding the role the healthcare professional's specialty plays …

Impact of smoking status on Health-Related Quality of Life (HRQoL) in cancer survivors Open

José Ignacio Nolazco, Bernard Rosner, Emily Roebuck, Cristiane Decat Bergerot, Elke Rammant , et al. · 2023

reports of data from original research.• Policy Case Studies -brief articles on policy development at a regional or national level.• Study Protocols -Articles describing a research protocol of a study.• Methodology Papers -Papers that pres…

The national utilization of nonoperative management for small renal masses over 10 years Open

Dejan K. Filipas, Edoardo Beatrici, José Ignacio Nolazco, Zhiyu Qian, Phillip Marks , et al. · 2023

Background Management of small renal masses often involves a nonoperative approach, but there is a paucity of information about the use and associated predictors of such approaches. This study aimed to determine the trends in and predictor…

The association of marital status with kidney cancer surgery morbidity - a retrospective cohort study Open

Yuzhe Tang, Marie-Thérèse Valovska, José Ignacio Nolazco, Kendrick Yim, Benjamin I. Chung , et al. · 2023

Purpose To better understand whether the marital status impacts 90-day postoperative outcomes following kidney cancer surgery. Methods We performed a retrospective cohort study of adult patients undergoing elective partial or radical nephr…

Pathological Outcomes of Patients With Advanced Renal Cell Carcinoma Who Receive Nephrectomy Following Immunotherapy Open

Justine Panian, Ava Saidian, Kevin Hakimi, Archana Ajmera, William J. Anderson , et al. · 2023

Background Even though cytoreductive nephrectomy (CN) was once the standard of care for patients with advanced renal cell carcinoma (RCC), its role in treatment has not been well analyzed or defined in the era of immunotherapy (IO). Materi…

The Association of Marital Status with Kidney Cancer Surgery Morbidity - A Retrospective Cohort Study Open

Yuzhe Tang, Marie-Thérèse Valovska, José Ignacio Nolazco, Kendrick Yim, Benjamin I. Chung , et al. · 2023

Purpose: To better understand whether the marital status impacts 90-day postoperative outcomes following kidney cancer surgery. Methods: We performed a retrospective cohort study of adult patients undergoing elective partial or radical nep…

The role of health-related quality of life in improving cancer outcomes. Open

José Ignacio Nolazco, Steven L. Chang · 2023

Active surveillance for complex renal cysts: is it time for III-F and IV-F? Open

José Ignacio Nolazco, Yuzhe Tang, Steven L. Chang · 2022

Understanding Hospital-Level Patterns of Nonoperative Management for Low-risk Thyroid and Kidney Cancer Open

Mara Koelker, Marieke J. Krimphove, Khalid Y. Alkhatib, Junaid Nabi, Lindsay E. Kuo , et al. · 2022

Importance There is a growing trend toward conservative management for certain low-risk cancers. Hospital and health-system factors may play a role in determining how these patients are managed. Objective To explore the contribution of hos…

Comparison of Long-term Outcomes for Young and Healthy Patients with cT1a and cT3a Renal Cell Carcinoma Treated with Partial Nephrectomy Open

Wei Shen Tan, Mara Koelker, Nicholas Campain, Alexander P. Cole, Muhieddine Labban , et al. · 2022

Partial nephrectomy (PN) is recommended for renal cell carcinoma (RCC) of <4 cm. We hypothesized that there is no difference in all-cause mortality (ACM) between cT1a, cT1b, and cT3a <4 cm RCC following PN. The National Cancer Database was…

Table of Contents Open

Mark Moss, Njira Lugogo, Mario Castro, Nicola A. Hanania, Andrea Ludwig-Sengpiel , et al. · 2022

Promoting the use of the PI-QUAL score for prostate MRI quality: results from the ESOR Nicholas Gourtsoyiannis teaching fellowship Open

Francesco Giganti, Alexander P. Cole, Fiona M. Fennessy, Timothy N. Clinton, Pedro Moreira , et al. · 2022

Objectives The Prostate Imaging Quality (PI-QUAL) score is a new metric to evaluate the diagnostic quality of multiparametric magnetic resonance imaging (MRI) of the prostate. This study assesses the impact of an intervention, namely a pro…

Integrative clinical and molecular characterization of translocation renal cell carcinoma Open

Ziad Bakouny, Ananthan Sadagopan, Praful Ravi, Nebiyou Y. Metaferia, Jiao Li , et al. · 2022

Radical versus partial nephrectomy and survival from stage T1 renal cell carcinoma in three prospective cohorts Open

Christopher Martin Sauer, Sarah C. Markt, Lorelei A. Mucci, Alejandro Sánchez, Steven L. Chang , et al. · 2021

Background Whether or not a survival difference exists between radical and partial nephrectomy for stage T1 renal cell carcinoma (RCC) is controversial. We therefore aimed to evaluate cancer-specific, other cause, and overall survival amon…

MP61-20 IMPACT OF TOBACCO USE ON POSTOPERATIVE MORBIDITY AND MORTALITY FOLLOWING SURGERY FOR RENAL MASSES Open

Kevin Melnick, Kendrick Yim, Madhur Nayan, Matthew Mossanen, Felipe Solferini de Carvalho , et al. · 2021

You have accessJournal of UrologyKidney Cancer: Epidemiology & Evaluation/Staging/Surveillance III (MP61)1 Sep 2021MP61-20 IMPACT OF TOBACCO USE ON POSTOPERATIVE MORBIDITY AND MORTALITY FOLLOWING SURGERY FOR RENAL MASSES Kevin Melnick, Ken…

Integrative Clinical and Molecular Characterization of Translocation Renal Cell Carcinoma Open

Ziad Bakouny, Ananthan Sadagopan, Praful Ravi, Nebiyou Y. Metaferia, Jiao Li , et al. · 2021

Translocation renal cell carcinoma (tRCC) is an aggressive and poorly-characterized subtype of kidney cancer driven by MiT/TFE gene fusions. Here, we define the landmarks of tRCC through an integrative analysis of 152 tRCC patients identif…

Progressive immune dysfunction with advancing disease stage in renal cell carcinoma Open

David A. Braun, Kelly Street, Kelly P. Burke, David L. Cookmeyer, Thomas Denize , et al. · 2021

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