Steven E. Wolf
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View article: 518 3D Monitoring of Burn Wounds Treated with Microporous Annealing Particle Hydrogel in a Porcine Model
518 3D Monitoring of Burn Wounds Treated with Microporous Annealing Particle Hydrogel in a Porcine Model Open
Introduction Split-thickness skin grafts (STSG) are the standard of care in many burn centers. However, donor skin availability and the length/complexity of grafting surgeries may limit their use. Existing hydrogels and biomaterials can he…
View article: 876 Effects of Antibiotic Resistance on Burn Outcomes
876 Effects of Antibiotic Resistance on Burn Outcomes Open
Introduction Antibiotic resistance remains the main challenge in burn wound infections. With the emergence of multidrug-resistant bacteria, this study aims to measure the effect of antibiotic resistance on health outcomes, including sepsis…
View article: 886 Incidence of Atrial Fibrillation in Burn Patients: A 6-Month Post-Burn Evaluation
886 Incidence of Atrial Fibrillation in Burn Patients: A 6-Month Post-Burn Evaluation Open
Introduction Burns trigger complex physiological responses including inflammation and sympathetic activation, elevating the risk of cardiovascular complications. Atrial fibrillation is a common event in burn centers which can have ramifica…
View article: 39 Silent Scars: Distinguishing the Psychiatric Morbidities Following Burn Injuries Between Males and Females
39 Silent Scars: Distinguishing the Psychiatric Morbidities Following Burn Injuries Between Males and Females Open
Introduction Burns have a profound impact on long-term psychiatric health. However, gender differences in mental health outcomes following burn injuries remain unclear. This retrospective cohort study aims to investigate gender differences…
View article: 591 The Use of Opioids in Adult Burn Patients: Long-term Dependency Risk and Outcomes
591 The Use of Opioids in Adult Burn Patients: Long-term Dependency Risk and Outcomes Open
Introduction Pain management in burn care remains a challenge in both acute and long-term treatment. Among non-steroidal anti-inflammatory drugs (NSAIDs), acetaminophen, gabapentinoids, and opioids are widely used as systemic analgesics, e…
View article: 931 Prescription Analysis of Antihistamines’ Use in Patients with Moderate to Severe Burns
931 Prescription Analysis of Antihistamines’ Use in Patients with Moderate to Severe Burns Open
Introduction Post-burn pruritus (PBP) significantly affects patients with moderate to severe burns (≥20% TBSA), causing discomfort and hindering recovery. Antihistamines, which block H1 receptors, are commonly prescribed for PBP, but large…
View article: 605 Evaluating ChatGPT’s Utility in Addressing Socioeconomic Disparities in Burn Patients: A Comparative Study with Google
605 Evaluating ChatGPT’s Utility in Addressing Socioeconomic Disparities in Burn Patients: A Comparative Study with Google Open
Introduction Patients from low socioeconomic status (SES) backgrounds often face significant barriers to quality burn care, including limited healthcare access, follow-up, and health literacy. Many rely on online resources like Google for …
View article: 938 Impact of Preexisting Substance Use Disorders on Prolonged Opioid Use and Postoperative Complications After Burns
938 Impact of Preexisting Substance Use Disorders on Prolonged Opioid Use and Postoperative Complications After Burns Open
Introduction Previous literature has highlighted the association between preexisting substance use disorders (SUDs) and adverse postoperative outcomes such as wound infections, postprocedural pain, and wound healing disruptions in burn pat…
View article: 577 Impact of Heparin and Enoxaparin Anticoagulant Prophylaxis on Improving Acute Mortality in Burn Patients
577 Impact of Heparin and Enoxaparin Anticoagulant Prophylaxis on Improving Acute Mortality in Burn Patients Open
Introduction Burn patients have a higher chance of developing thromboembolic complications leading to worsened mortality rates so prophylactic anticoagulation is important. Anticoagulants such as enoxaparin, a low molecular weight heparin …
View article: 566 Covariate Analysis of Performance of Multi-Spectral Imaging System Augmented with Artificial Intelligence
566 Covariate Analysis of Performance of Multi-Spectral Imaging System Augmented with Artificial Intelligence Open
Introduction Burn wound assessment is essential for effective clinical management and prompt intervention. Typically, burn assessments rely on the clinician’s judgment to discriminate superficial partial-thickness (“healing”) from deep par…
View article: 885 Heterotopic Ossification After Burn Injury Results in Worse Outcomes
885 Heterotopic Ossification After Burn Injury Results in Worse Outcomes Open
Introduction Heterotopic ossification (HO) is the formation of extra-skeletal bone within soft tissue that occurs after injuries like severe burns. Development of HO complicates healing after injury. We aimed to elucidate factors influenci…
View article: 65 Reducing High Mobility Group Box 1 Activities to Prevent Scald Burn Wound Progression in Rats
65 Reducing High Mobility Group Box 1 Activities to Prevent Scald Burn Wound Progression in Rats Open
Introduction Severe burns trigger hyperinflammatory and hypermetabolic responses, leading to systemic organ damage. High mobility group box 1 (HMGB1) belongs to damage associated molecular pattern (DAMPs) which are released from burn wound…
View article: Estrogen Treatment Lowers the Risk of Complications in Menopausal Women with Mild Burn Injury
Estrogen Treatment Lowers the Risk of Complications in Menopausal Women with Mild Burn Injury Open
Background and Objectives: Postmenopausal women are often treated with exogenous female hormones to alleviate physical symptoms and support mental health. We posit that women treated with estrogen fare better following burn injury. Materia…
View article: The Effect of Diabetes Mellitus Severity on Foot & Ankle Burn Recovery
The Effect of Diabetes Mellitus Severity on Foot & Ankle Burn Recovery Open
Background: Diabetic patients often present with complex limb pathology, resulting in impaired sensation in the distal extremities making tactile injuries such as burns difficult to notice. We posit that poorly controlled diabetes mellitus…
View article: Establishing a Collaborative Genomic Repository for Adult Burn Survivors: A Burn Model System Feasibility Study
Establishing a Collaborative Genomic Repository for Adult Burn Survivors: A Burn Model System Feasibility Study Open
In this study, we aimed to integrate a genetic repository with an existing longitudinal national burn database. We set out two primary objectives, namely (1) to develop standard operating procedures for genetic sample collection and storag…
View article: Mild burn amplifies the locomotive depression in demyelinated mice without muscle pathophysiological changes
Mild burn amplifies the locomotive depression in demyelinated mice without muscle pathophysiological changes Open
Introduction Patients with mild burns take most accounts, however, the impact of mild burns is less known. Nerve destruction leads to muscle atrophy. We posit that even mild burn injury could worsen demyelinated nerves related to muscle pa…
View article: Elevated Cardiac Troponin I Level Associated to Cardiac Dysfunction in Burned Patients
Elevated Cardiac Troponin I Level Associated to Cardiac Dysfunction in Burned Patients Open
Severely burned patients often develop cardiac dysfunction and heart failure. The purpose of this retrospective study is to evaluate the role of cardiac troponin I (cTI) and its association to patients with burns. Patients deidentified dat…
View article: Nonsteroidal Anti-Inflammatory Drugs Decrease Coagulopathy Incidence in Severe Burn Patients
Nonsteroidal Anti-Inflammatory Drugs Decrease Coagulopathy Incidence in Severe Burn Patients Open
The study investigated the impact of nonsteroidal anti-inflammatory drugs (NSAIDs) on burn-induced coagulopathy in severely burned patients. Patients with a greater than 20% TBSA were identified in the TriNetX research network and categori…
View article: 86 Hypothyroidism Associated with Increased Risk of Developing Contractures and Skin Disorders in Severe Burn Patients
86 Hypothyroidism Associated with Increased Risk of Developing Contractures and Skin Disorders in Severe Burn Patients Open
Introduction Patients who suffer severe burns are prone to develop various musculoskeletal and dermatological complications in the years following their injury. Hypothyroidism is classically associated with a number of muscle and skin diso…
View article: 759 Burn Injury Impacts Estrogen-treated Postmenopausal Women
759 Burn Injury Impacts Estrogen-treated Postmenopausal Women Open
Introduction Postmenopausal women are often treated with exogenous female hormones to alleviate mental and physical symptoms. Basic research studies showed the benefit of estrogen treatment on the improvement of cardiac function following …
View article: 703 Vasopressors in Early Resuscitation of Severe Burn Injuries
703 Vasopressors in Early Resuscitation of Severe Burn Injuries Open
Introduction Fluid resuscitation is the main treatment for preventing burn shock. Rescue therapies are usually initiated if patients respond poorly to fluid resuscitation with crystalloids alone. Vasopressors, often in combination with col…
View article: 705 C. difficile Enterocolitis Diagnosis Elevated in Critically Ill Burn Patients Following Antibiotic Treatment
705 C. difficile Enterocolitis Diagnosis Elevated in Critically Ill Burn Patients Following Antibiotic Treatment Open
Introduction C. difficile colitis (C diff colitis) is identified in up to 500k infections/year in the US, with up to 30,000 people per year dying with the diagnosis. Previous studies established risk factors for this condition including lo…
View article: 588 Early Physical Therapy Improves Burn Rehabilitation: Nationwide Study of Patients ≤30% Total Burn Surface Area
588 Early Physical Therapy Improves Burn Rehabilitation: Nationwide Study of Patients ≤30% Total Burn Surface Area Open
Introduction While the benefits of physical therapy (PT) in burn patient rehabilitation is highlighted to great extent in literature, there are no national estimates on the effects of time from admission to initial PT evaluation. This stud…
View article: 85 Sole Propofol Use in Burn Patients Is Associated with Better Postprocedural Outcomes Than Using Propofol-Ketamine
85 Sole Propofol Use in Burn Patients Is Associated with Better Postprocedural Outcomes Than Using Propofol-Ketamine Open
Introduction Propofol and its combination with ketamine have been used as sedatives in burn patients undergoing operative procedures such as surgical debridement and wound care. Although research has been conducted on comparing the complic…
View article: 48 Genital Burns Are Associated with Worse Psychosocial and Physical Outcomes
48 Genital Burns Are Associated with Worse Psychosocial and Physical Outcomes Open
Introduction Genital burns (GB) represent a specialized subset of injuries with a profound impact on quality of life and psychosexual health. Analysis of GB is notably sparse in the current literature. This study aims to address GB short a…
View article: 123 National Study of the Increased Incidence of Complex Regional Pain Syndrome Following Severe Burn Injury
123 National Study of the Increased Incidence of Complex Regional Pain Syndrome Following Severe Burn Injury Open
Introduction Complex Regional Pain Syndrome (CRPS) is a clinical condition that presents after an operation, trauma, or burn injury with allodynia, hyperalgesia, and myasthenia. The etiology of CRPS remains poorly understood and there is a…
View article: 500 Anticoagulant Use Is Associated with Different Outcomes in Pediatric and Adult Burn Patients
500 Anticoagulant Use Is Associated with Different Outcomes in Pediatric and Adult Burn Patients Open
Introduction Anticoagulation therapy in pediatric burn patients remains an under-researched area of burn medicine lacking guidelines or scores to establish standardized therapy. The aim of this study is to evaluate the use of anticoagulant…
View article: 596 Elevated Cardiac Troponin I Level Within 72 Hours Correlated to Cardiac Dysfunction in Burned Patients
596 Elevated Cardiac Troponin I Level Within 72 Hours Correlated to Cardiac Dysfunction in Burned Patients Open
Introduction Severe burned patients are under a hyperadrenergic and hypermetabolic states. Without proper treatment, patients developed cardiac dysfunction and heart failure. Cardiac Troponin I (cTI) is released from cardiac tissue which i…
View article: 57 HIV Infection Increases Risk of Sepsis and Other Complications in Burn Patients
57 HIV Infection Increases Risk of Sepsis and Other Complications in Burn Patients Open
Introduction Infection with human immunodeficiency virus (HIV) confers an immunocompromised status that renders patients susceptible to various pathogen-related morbidities, eventually progressing to acquired immunodeficiency syndrome (AID…