Stuart A. Macgregor
YOU?
Author Swipe
View article: Correction to “The Photochemical Mediated Ring Contraction of 4<i>H</i>-1,2,6-Thiadiazines To Afford 1,2,5-Thiadiazol-3(2<i>H</i>)-one 1-Oxides”
Correction to “The Photochemical Mediated Ring Contraction of 4<i>H</i>-1,2,6-Thiadiazines To Afford 1,2,5-Thiadiazol-3(2<i>H</i>)-one 1-Oxides” Open
View article: Evidence for a fully Cu(II)-catalyzed CuAAC reaction: A combined experimental and computational study
Evidence for a fully Cu(II)-catalyzed CuAAC reaction: A combined experimental and computational study Open
The Cu-catalyzed azide-alkyne cycloaddition (CuAAC) reaction is one of the most broadly applied catalytic processes, with significant applications throughout synthetic chemistry, drug discovery, chemical biology, and materials science. Thi…
View article: [B(O<sub>2</sub>C<sub>2</sub>(CF<sub>3</sub>)<sub>4</sub>)<sub>2</sub>]<sup>−</sup> ([FPB]<sup>−</sup>): Repurposing This Weakly Coordinating Anion for Solid-State Molecular Organometallic (SMOM) Chemistry
[B(O<sub>2</sub>C<sub>2</sub>(CF<sub>3</sub>)<sub>4</sub>)<sub>2</sub>]<sup>−</sup> ([FPB]<sup>−</sup>): Repurposing This Weakly Coordinating Anion for Solid-State Molecular Organometallic (SMOM) Chemistry Open
The perfluoropinacol borate-based anion [B-(O2C2(CF3)4)2]-, [FPB] -, is developed as a weakly coordinating anion for single-crystal to single-crystal organ…
View article: The Mechanism of Ruthenium‐Catalyzed Directed C─H Arylation of Arenes: The Key Role of Bis‐Cyclometalated Intermediates
The Mechanism of Ruthenium‐Catalyzed Directed C─H Arylation of Arenes: The Key Role of Bis‐Cyclometalated Intermediates Open
The mechanism of Ru‐catalyzed N ‐directed C‐H ortho ‐arylation with haloarenes has been under intense scrutiny over the last decade, with conflicting proposals concerning the relevance of various catalytic intermediates and the nature of t…
View article: The Mechanism of Ruthenium‐Catalyzed Directed C─H Arylation of Arenes: The Key Role of Bis‐Cyclometalated Intermediates
The Mechanism of Ruthenium‐Catalyzed Directed C─H Arylation of Arenes: The Key Role of Bis‐Cyclometalated Intermediates Open
The mechanism of Ru‐catalyzed N ‐directed C‐H ortho ‐arylation with haloarenes has been under intense scrutiny over the last decade, with conflicting proposals concerning the relevance of various catalytic intermediates and the nature of t…
View article: Square Planar Ru(<i><sup>i</sup></i>Pr<sub>2</sub>PCH<sub>2</sub>CH<sub>2</sub>NH)<sub>2</sub> and its Role in Fast and Selective Catalytic Amine–Borane Dehydropolymerization to Form High Molecular Weight Polyaminoboranes
Square Planar Ru(<i><sup>i</sup></i>Pr<sub>2</sub>PCH<sub>2</sub>CH<sub>2</sub>NH)<sub>2</sub> and its Role in Fast and Selective Catalytic Amine–Borane Dehydropolymerization to Form High Molecular Weight Polyaminoboranes Open
Addition of t BuOK to orange RuCl 2 ( i Pr 2 PCH 2 CH 2 NH 2 ) 2 forms the pink, square planar, Ru(II) complex Ru( i Pr 2 PCH 2 CH 2 NH) 2 . This is an active catalyst (ToF 250 s −1 ) for the dehydropolymerization of H 3 B·NMeH 2 to give h…
View article: Expanding metal catalyzed arene C–H borylation beyond boronate esters
Expanding metal catalyzed arene C–H borylation beyond boronate esters Open
The metal-catalyzed intermolecular C–H borylation of arenes is an extremely powerful C–H functionalization methodology. However, to date it is effectively restricted to forming organo-boronate esters (Aryl–B(OR)2) with its application to f…
View article: An Operationally Unsaturated Iridium-Pincer Complex That C–H Activates Methane and Ethane in the Crystalline Solid-State
An Operationally Unsaturated Iridium-Pincer Complex That C–H Activates Methane and Ethane in the Crystalline Solid-State Open
The known complex [Ir(tBu-PONOP)MeH][BArF4], 1[BArF4] [tBu-PONOP = κ3-2,6-(tBu2PO)
View article: ZnH<sub>2</sub> as a Precursor to Catalytically Active Ru–ZnH Heterometallic Complexes
ZnH<sub>2</sub> as a Precursor to Catalytically Active Ru–ZnH Heterometallic Complexes Open
Reaction of [Ru(IPr)2(CO)H][BArF4] (1; IPr = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene; BArF4 = B{3,5(CF3)2C6H3}4) …
View article: Catalytic transfer zincation using ammonium cations
Catalytic transfer zincation using ammonium cations Open
This work reports the first catalytic electrophilic transfer zincation in which the use of the right alkyl group is essential. This enables a zinc-catalysed glovebox-free borylation with (H–BBN) 2 .
View article: Ligand non-innocence and an unusual σ-bond metathesis step enables catalytic borylation using 9-borabicyclo-[3.3.1]-nonane
Ligand non-innocence and an unusual σ-bond metathesis step enables catalytic borylation using 9-borabicyclo-[3.3.1]-nonane Open
Herein, we report a Zn/Al catalysed heteroarene C–H borylation using 9-borabicyclo-[3.3.1]-nonane. DFT studies indicated an unusual σ-bond metathesis process between NacNacZn–Aryl and the dimeric hydroborane, involving ligand non-innocence.
View article: Isolobal Cationic Iridium Dihydride and Dizinc Complexes: A Dual Role for the ZnR Ligand Enhances H<sub>2</sub> Activation
Isolobal Cationic Iridium Dihydride and Dizinc Complexes: A Dual Role for the ZnR Ligand Enhances H<sub>2</sub> Activation Open
The reaction of [Ir(IPr)2H2][BArF4] (1; IPr = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene; BArF4 = B{C6H3(3,5-CF3)2}<…
View article: Solid/Gas <i>In Crystallo</i> Reactivity of an Ir(I) Methylidene Complex
Solid/Gas <i>In Crystallo</i> Reactivity of an Ir(I) Methylidene Complex Open
In crystallo stabilization of known, but solution unstable, methylidene complex [Ir(tBu-PONOP)(=CH2)][BArF 4] allows single-crystal to single-crystal solid/gas reactivity associated with t…
View article: A Gold(I)–Acetylene Complex Synthesised using Single‐Crystal Reactivity
A Gold(I)–Acetylene Complex Synthesised using Single‐Crystal Reactivity Open
Using single‐crystal to single‐crystal solid/gas reactivity the gold(I) acetylene complex [Au( L1 )(η 2 ‐HC≡CH)][BAr F 4 ] is cleanly synthesized by addition of acetylene gas to single crystals of [Au( L1 )(CO)][BAr F 4 ] [ L1 =tris‐2‐(4,4…
View article: A Gold(I)–Acetylene Complex Synthesised using Single‐Crystal Reactivity
A Gold(I)–Acetylene Complex Synthesised using Single‐Crystal Reactivity Open
Using single‐crystal to single‐crystal solid/gas reactivity the gold(I) acetylene complex [Au( L1 )(η 2 ‐HC≡CH)][BAr F 4 ] is cleanly synthesized by addition of acetylene gas to single crystals of [Au( L1 )(CO)][BAr F 4 ] [ L1 =tris‐2‐(4,4…
View article: Transition Metal‐Free Catalytic C−H Zincation and Alumination
Transition Metal‐Free Catalytic C−H Zincation and Alumination Open
C−H metalation is the most efficient method to prepare aryl–zinc and –aluminium complexes that are ubiquitous nucleophiles. Virtually all C−H metalation routes to form Al/Zn organometallics require stoichiometric, strong Brønsted bases wit…
View article: Transition Metal‐Free Catalytic C−H Zincation and Alumination
Transition Metal‐Free Catalytic C−H Zincation and Alumination Open
C−H metalation is the most efficient method to prepare aryl–zinc and –aluminium complexes that are ubiquitous nucleophiles. Virtually all C−H metalation routes to form Al/Zn organometallics require stoichiometric, strong Brønsted bases wit…
View article: Catalyst Design for Rh-Catalyzed Arene and Alkane C–H Borylation: The NHC Affects the Induction Period, and Indenyl is Superior to Cp
Catalyst Design for Rh-Catalyzed Arene and Alkane C–H Borylation: The NHC Affects the Induction Period, and Indenyl is Superior to Cp Open
In order to establish design criteria for Rh C-H borylation catalysts, analogues of the successful catalyst [Rh(Ind)(SIDipp)(COE)] (Ind = η5-indenyl, SIDipp = 1,3-bis(2,6-diisopropylphenyl)-4,5-dihydroimidazol-2-ylidene, and COE…
View article: Transition Metal-Free Catalytic C−H Zincation and C−H Alumination
Transition Metal-Free Catalytic C−H Zincation and C−H Alumination Open
C−H metalation is the most efficient method to prepare aryl–zinc and –aluminum complexes that are highly useful nucleophiles. Virtually all C–H metalation routes to form Al or Zn organometallic reagents require stoichiometric, strong Brøns…
View article: CCDC 2304314: Experimental Crystal Structure Determination
CCDC 2304314: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2304313: Experimental Crystal Structure Determination
CCDC 2304313: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2304317: Experimental Crystal Structure Determination
CCDC 2304317: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2304316: Experimental Crystal Structure Determination
CCDC 2304316: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2304318: Experimental Crystal Structure Determination
CCDC 2304318: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2304315: Experimental Crystal Structure Determination
CCDC 2304315: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Contrasting reactivity of B–Cl and B–H bonds at [Ni(IMes)<sub>2</sub>] to form unsupported Ni-boryls
Contrasting reactivity of B–Cl and B–H bonds at [Ni(IMes)<sub>2</sub>] to form unsupported Ni-boryls Open
Whilst the oxidative addition of B–Cl bonds at [Ni(IMes) 2 ] forms unsupported Ni-boryls the corresponding B–H bonds do not react via oxidative addition. Computational studies show that this is due to a fundamental change in mechanism.
View article: CCDC 2168213: Experimental Crystal Structure Determination
CCDC 2168213: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2167999: Experimental Crystal Structure Determination
CCDC 2167999: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2168264: Experimental Crystal Structure Determination
CCDC 2168264: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2168147: Experimental Crystal Structure Determination
CCDC 2168147: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …