Stuart C. D. Kennington
YOU?
Author Swipe
View article: Head-to-Tail Selective [2 + 2 + 2] Cycloadditions of Bisallenes Enabled by Ligand-Free Nickel(0)
Head-to-Tail Selective [2 + 2 + 2] Cycloadditions of Bisallenes Enabled by Ligand-Free Nickel(0) Open
View article: Direct, Stereodivergent, and Catalytic Michael Additions of Thioimides to α,β‐Unsaturated Aldehydes – Total Synthesis of Tapentadol
Direct, Stereodivergent, and Catalytic Michael Additions of Thioimides to α,β‐Unsaturated Aldehydes – Total Synthesis of Tapentadol Open
Direct and stereodivergent Michael additions of N ‐acyl 1,3‐thiazinane‐2‐thiones to α,β‐unsaturated aldehydes catalyzed by chiral nickel(II) complexes are reported. The reactions proceed with a remarkable regio‐, diastereo‐, and enantiosel…
View article: Copper(I) Iodide Catalyzed [3 + 3] Annulation of Iodonium Ylides with Pyridinium 1,4-Zwitterionic Thiolates for the Synthesis of 1,4-Oxathiin Scaffolds
Copper(I) Iodide Catalyzed [3 + 3] Annulation of Iodonium Ylides with Pyridinium 1,4-Zwitterionic Thiolates for the Synthesis of 1,4-Oxathiin Scaffolds Open
The selective assembly of the 1,4-oxathiin nucleus has been treated as a powerful strategy to access this scaffold present in molecules with very interesting properties. In this study, the chameleon-like reactivity of pyridinium 1,4-zwitte…
View article: CCDC 2260600: Experimental Crystal Structure Determination
CCDC 2260600: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2117967: Experimental Crystal Structure Determination
CCDC 2117967: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2149681: Experimental Crystal Structure Determination
CCDC 2149681: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2190990: Experimental Crystal Structure Determination
CCDC 2190990: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2190989: Experimental Crystal Structure Determination
CCDC 2190989: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Protected <i>syn</i>-Aldol Compounds from Direct, Catalytic, and Enantioselective Reactions of <i>N</i>-Acyl-1,3-oxazinane-2-thiones with Aromatic Acetals
Protected <i>syn</i>-Aldol Compounds from Direct, Catalytic, and Enantioselective Reactions of <i>N</i>-Acyl-1,3-oxazinane-2-thiones with Aromatic Acetals Open
A direct and asymmetric syn-aldol reaction of N-acyl-1,3-oxazinane-2-thiones with dialkyl acetals from aromatic acetals in the presence of 2-5 mol % [DTBM-SEGPHOS]NiCl2, TMSOTf, and lutidine has been developed. It …
View article: Direct and Asymmetric Aldol Reactions of <i>N</i>‐Azidoacetyl‐1,3‐thiazolidine‐2‐thione Catalyzed by Chiral Nickel(II) Complexes. A New Approach to the Synthesis of β‐Hydroxy‐α‐Amino Acids
Direct and Asymmetric Aldol Reactions of <i>N</i>‐Azidoacetyl‐1,3‐thiazolidine‐2‐thione Catalyzed by Chiral Nickel(II) Complexes. A New Approach to the Synthesis of β‐Hydroxy‐α‐Amino Acids Open
A direct and asymmetric triisopropylsilyltrifluoromethanesulfonate (TIPSOTf) mediated aldol reaction of N ‐azidoacetyl‐1,3‐thiazolidine‐2‐thione with aromatic aldehydes catalyzed by a chiral nickel(II)‐Tol‐BINAP complex has been developed …
View article: Synthesis of [(R)-DTBM-SEGPHOS]NiCl2 for the Enantioselective Acetal Formation from N-Propanoyl-1,3-Thiazinane-2-thione and Trimethyl Orthoformate
Synthesis of [(R)-DTBM-SEGPHOS]NiCl2 for the Enantioselective Acetal Formation from N-Propanoyl-1,3-Thiazinane-2-thione and Trimethyl Orthoformate Open
0.5 0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 5.0 5.5 6.0 6.5 7.0 7.5 8.0 8.5 9.0 9.5 10.0 f1 (ppm)
View article: CCDC 2062607: Experimental Crystal Structure Determination
CCDC 2062607: Experimental Crystal Structure Determination Open
View article: Direct and Enantioselective Aldol Reactions Catalyzed by Chiral Nickel(II) Complexes
Direct and Enantioselective Aldol Reactions Catalyzed by Chiral Nickel(II) Complexes Open
A direct and asymmetric aldol reaction of N ‐acyl thiazinanethiones with aromatic aldehydes catalyzed by chiral nickel(II) complexes is reported. The reaction gives the corresponding O ‐TIPS‐protected anti ‐aldol adducts in high yields and…
View article: Direct and Enantioselective Aldol Reactions Catalyzed by Chiral Nickel(II) Complexes
Direct and Enantioselective Aldol Reactions Catalyzed by Chiral Nickel(II) Complexes Open
A direct and asymmetric aldol reaction of N ‐acyl thiazinanethiones with aromatic aldehydes catalyzed by chiral nickel(II) complexes is reported. The reaction gives the corresponding O ‐TIPS‐protected anti ‐aldol adducts in high yields and…
View article: Synthesis and Acylation of 1,3-Thiazinane-2-thione
Synthesis and Acylation of 1,3-Thiazinane-2-thione Open
0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 5.0 5.5 6.0 6.5 7.0 7.5 8.0 8.5 9.0 9.5 10.0 10.5 f1 (ppm)
View article: The development of new, direct and asymmetric Ni(II) catalysed carbon-carbon bond forming reactions and their application to total synthesis
The development of new, direct and asymmetric Ni(II) catalysed carbon-carbon bond forming reactions and their application to total synthesis Open
This thesis focuses on the search for new methodologies for the direct, stereoselective and catalytic formation of carbon-carbon bonds through the formation of chiral nickel(II) enolate species and the application of such methods to the sy…
View article: CCDC 1984006: Experimental Crystal Structure Determination
CCDC 1984006: Experimental Crystal Structure Determination Open
View article: CCDC 1857787: Experimental Crystal Structure Determination
CCDC 1857787: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1835692: Experimental Crystal Structure Determination
CCDC 1835692: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1857788: Experimental Crystal Structure Determination
CCDC 1857788: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1536448: Experimental Crystal Structure Determination
CCDC 1536448: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1536449: Experimental Crystal Structure Determination
CCDC 1536449: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …