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View article: Needle‐free, Liquid Metal‐embedded Electrospray Deposition System for Controlled Microdroplet Printing
Needle‐free, Liquid Metal‐embedded Electrospray Deposition System for Controlled Microdroplet Printing Open
Electrospray systems have been widely utilized in biomedical, pharmaceutical, and materials science applications due to their ability to enable precise liquid manipulation and efficient ionization. However, conventional electrospray techno…
View article: The 96‐Puddle Paper Plate as a Versatile Lab‐on‐Paper Platform
The 96‐Puddle Paper Plate as a Versatile Lab‐on‐Paper Platform Open
Microfluidic paper‐based analytical devices (µPADs) have facilitated the detection of a wide range of analytes, spanning human health indicators and environmental contaminants. However, their diverse designs necessitate specialized analyti…
View article: Evaluation of Pre-Transfusion Crossmatch Test Using Microscanner C3
Evaluation of Pre-Transfusion Crossmatch Test Using Microscanner C3 Open
A pre-transfusion crossmatch test is crucial for ensuring safe blood transfusions by identifying the compatibility between donor and recipient blood samples. Conventional tube methods for crossmatching have limitations, including subjectiv…
View article: Microfluidic Electroporation Arrays for Investigating Electroporation-Induced Cellular Rupture Dynamics
Microfluidic Electroporation Arrays for Investigating Electroporation-Induced Cellular Rupture Dynamics Open
Electroporation is pivotal in bioelectrochemistry for cellular manipulation, with prominent applications in drug delivery and cell membrane studies. A comprehensive understanding of pore generation requires an in-depth analysis of the crit…
View article: Multi-modal biosensing enabled by on-chip nano-corrugated graphene
Multi-modal biosensing enabled by on-chip nano-corrugated graphene Open
We present a nano-corrugation graphene (NCGr)-based device, which can support diverse detection strategies. A single NCGr device can exhibit three different modes of biomolecular sensing: electrolyte-gated field-effect transistor (FET) sen…
View article: Therapeutic Potential of Traditional Oriental Medicines in Targeting Tau Pathology: Insights from Cell-free and Cell-based Screening
Therapeutic Potential of Traditional Oriental Medicines in Targeting Tau Pathology: Insights from Cell-free and Cell-based Screening Open
Background: Traditional Oriental Medicines (TOMs) formulated using a variety of medicinal plants have a low risk of side effects. In previous studies, five TOMs, namely Dangguijakyaksan, Hwanglyeonhaedoktang, Ukgansan, Palmijihwanghwan, an…
View article: Highly Localized Chemical Sampling at Subsecond Temporal Resolution Enabled with a Silicon Nanodialysis Platform at Nanoliter per Minute Flows
Highly Localized Chemical Sampling at Subsecond Temporal Resolution Enabled with a Silicon Nanodialysis Platform at Nanoliter per Minute Flows Open
Microdialysis (MD) is a versatile and powerful technique for chemical profiling of biological tissues and is widely used for quantification of neurotransmitters, neuropeptides, metabolites, biomarkers, and drugs in the central nervous syst…
View article: Dual regulatory effects of neferine on amyloid-β and tau aggregation studied by in silico, in vitro, and lab-on-a-chip technology
Dual regulatory effects of neferine on amyloid-β and tau aggregation studied by in silico, in vitro, and lab-on-a-chip technology Open
Alzheimer's disease (AD) is characterized by the presence of two critical pathogenic factors: amyloid-β (Aβ) and tau. Aβ and tau become neurotoxic aggregates via self-assembly, and these aggregates contribute to the pathogenesis of AD. The…
View article: Hydrophobic Barriers for Directing <i>Physarum polycephalum</i> Propulsion and Navigation
Hydrophobic Barriers for Directing <i>Physarum polycephalum</i> Propulsion and Navigation Open
Physarum polycephalum (P. polycephalum) is a unicellular protist with unique properties, such as learning and remembering in its cultured environment without a brain or central nervous system. The organism has been extensively used in morp…
View article: Simple Point-of-Care Nucleic Acid Amplification Test for Rapid SARS-CoV-2 Infection Diagnosis
Simple Point-of-Care Nucleic Acid Amplification Test for Rapid SARS-CoV-2 Infection Diagnosis Open
After three years of the SARS-CoV-2 pandemic, the demand for developing field-deployable point-of-care (PoC) molecular diagnostic tests has increased. Although RT-qPCR is the molecular diagnostic gold standard and is accurate, it is not re…
View article: Highly localized chemical sampling at sub-second temporal resolution enabled with a silicon nanodialysis platform at exceedingly slow flows
Highly localized chemical sampling at sub-second temporal resolution enabled with a silicon nanodialysis platform at exceedingly slow flows Open
Microdialysis (MD) is a versatile and powerful technique for chemical profiling of biological tissues and is widely used for quantification of neurotransmitters, neuropeptides, metabolites, biomarkers, and drugs in the central nervous syst…
View article: Recycled, Contaminated, Crumpled Aluminum Foil‐Driven Triboelectric Nanogenerator
Recycled, Contaminated, Crumpled Aluminum Foil‐Driven Triboelectric Nanogenerator Open
With rapid urbanization and global population growth, the amount of wasted aluminum foil is significantly increasing. Most deformed and contaminated foil is difficult to recycle; hence, it is landfilled or incinerated, causing environmenta…
View article: Integrated silicon microfluidic chip for picoliter-scale analyte segmentation and microscale printing for mass spectrometry imaging
Integrated silicon microfluidic chip for picoliter-scale analyte segmentation and microscale printing for mass spectrometry imaging Open
A silicon integrated microfluidics system prints picoliter-segmented analytes for attomole-level chemical analysis with mass spectrometry imaging.
View article: Fast Responsive, Reversible Colorimetric Nanoparticle-Hydrogel Complexes for pH Monitoring
Fast Responsive, Reversible Colorimetric Nanoparticle-Hydrogel Complexes for pH Monitoring Open
Hydrogels containing redox-sensitive colorimetric nanoparticles (NPs) have been used to sense ambient pH in many fields owing to their simple and fast visualization capabilities. However, real-time pH monitoring still has limitations due t…
View article: On-Chip Single-Cell Bioelectrical Analysis for Identification of Cell Electrical Phenotyping in Response to Sequential Electric Signal Modulation
On-Chip Single-Cell Bioelectrical Analysis for Identification of Cell Electrical Phenotyping in Response to Sequential Electric Signal Modulation Open
In recent years, an interesting biomarker called membrane breakdown voltage has been examined using artificial planar lipid bilayers. Even though they have great potential to identify cell electrical phenotyping for distinguishing similar …
View article: Amyloid Formation in Nanoliter Droplets
Amyloid Formation in Nanoliter Droplets Open
Processes that monitor the nucleation of amyloids and characterize the formation of amyloid fibrils are vital to medicine and pharmacology. In this study, we observe the nucleation and formation of lysozyme amyloid fibrils using a facile m…
View article: Investigating Time-Varying Effects of Stakeholder Relations on Firm Performance through Brand Equity
Investigating Time-Varying Effects of Stakeholder Relations on Firm Performance through Brand Equity Open
From the resource-based view of the firm, good stakeholder relations provide sustainable competitive advantages. To manage their scarce resources effectively, firms should understand how (1) multiple stakeholder relations influence firm pe…
View article: Colorimetric Sensing of Lactate in Human Sweat Using Polyaniline Nanoparticles-Based Sensor Platform and Colorimeter
Colorimetric Sensing of Lactate in Human Sweat Using Polyaniline Nanoparticles-Based Sensor Platform and Colorimeter Open
In emergency medicine, the lactate level is commonly used as an indicator of the severity and response to the treatment of hypoperfusion-related diseases. Clinical lactate measurements generally require 3 h for clinical determination. To i…
View article: Developing a multiplex loop-mediated isothermal amplification assay (LAMP) to determine severe fever with thrombocytopenia syndrome (SFTS) and scrub typhus
Developing a multiplex loop-mediated isothermal amplification assay (LAMP) to determine severe fever with thrombocytopenia syndrome (SFTS) and scrub typhus Open
Severe fever with thrombocytopenia syndrome (SFTS) and scrub typhus are endemic zoonotic diseases that pose significant public health threats in East Asia. As these two diseases share common clinical features, as well as overlapping diseas…
View article: Droplet-assisted electrospray phase separation using an integrated silicon microfluidic platform
Droplet-assisted electrospray phase separation using an integrated silicon microfluidic platform Open
We report on a silicon microfluidic platform that enables integration of transparent μm-scale microfluidic channels, an on-chip pL-volume droplet generator, and a nano-electrospray ionization emitter that enables spatial and temporal phase…
View article: Development of a Multiplex Loop-Mediated Isothermal Amplification Assay for Diagnosis of Plasmodium spp., Plasmodium falciparum and Plasmodium vivax
Development of a Multiplex Loop-Mediated Isothermal Amplification Assay for Diagnosis of Plasmodium spp., Plasmodium falciparum and Plasmodium vivax Open
Malaria, caused by the parasite Plasmodium and transmitted by mosquitoes, is an epidemic that mainly occurs in tropical and subtropical regions. As treatments differ across species of malarial parasites, there is a need to develop rapid di…
View article: Ultrasensitive Detection of Dopamine, IL‐6 and SARS‐CoV‐2 Proteins on Crumpled Graphene FET Biosensor
Ultrasensitive Detection of Dopamine, IL‐6 and SARS‐CoV‐2 Proteins on Crumpled Graphene FET Biosensor Open
Universal platforms for biomolecular analysis using label‐free sensing modalities can address important diagnostic challenges. Electrical field effect‐sensors are an important class of devices that can enable point‐of‐care sensing by probi…
View article: Droplet Microfluidics with MALDI-MS Detection: The Effects of Oil Phases in GABA Analysis
Droplet Microfluidics with MALDI-MS Detection: The Effects of Oil Phases in GABA Analysis Open
Microfluidic and mass spectrometry (MS) methods are widely used to sample and probe the chemical composition of biological systems to elucidate chemical correlates of their healthy and disease states. Though matrix-assisted laser desorptio…
View article: Computationally Assisted Design and Selection of Maneuverable Biological Walking Machines
Computationally Assisted Design and Selection of Maneuverable Biological Walking Machines Open
Biohybrid Walkers In article number 2000237, Rashid Bashir, Mattia Gazzola, and co-workers present a maneuverable dual-ring biohybrid walker designed and selected through a systematic approach based on modeling, simulation, and fabrication…
View article: Power Distance as a Variable in Assessing Employees' Behavior towards Information Security Policy Compliance in a High-Power Distance Society: An Exploratory Study
Power Distance as a Variable in Assessing Employees' Behavior towards Information Security Policy Compliance in a High-Power Distance Society: An Exploratory Study Open
Information security is a concern of every business, therefore the need for employees to comply with a policy that would protect the organization's assets. The model developed for this research was based on Protection Motivation Theory, Th…
View article: Computationally Assisted Design and Selection of Maneuverable Biological Walking Machines
Computationally Assisted Design and Selection of Maneuverable Biological Walking Machines Open
The intriguing opportunities enabled by the use of living components in biological machines have spurred the development of a variety of muscle‐powered biohybrid robots in recent years. Among them, several generations of tissue‐engineered …
View article: Computationally assisted design and selection of maneuverable biological walking machines
Computationally assisted design and selection of maneuverable biological walking machines Open
The intriguing opportunities enabled by the use of living components in biological machines have spurred the development of a variety of muscle-powered bio-hybrid robots in recent years. Among them, several generations of bio-hybrid walker…