Subasini Uthirapathy
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View article: Global patterns of antibiotic resistance in group B Streptococcus: a systematic review and meta-analysis
Global patterns of antibiotic resistance in group B Streptococcus: a systematic review and meta-analysis Open
Objectives Streptococcus agalactiae , or group B Streptococcus (GBS), is a significant pathogen associated with severe infections in neonates, particularly sepsis and meningitis. The increasing prevalence of antibiotic resistance among GBS…
View article: Exosomal lncRNAs in the Tumor Angiogenesis: As Therapeutic Targets in Cancer Treatment
Exosomal lncRNAs in the Tumor Angiogenesis: As Therapeutic Targets in Cancer Treatment Open
Exosomes, as mediators of intercellular communication, can be released from different types of cells and regulate the function of the target cell by transferring cargo, such as proteins, DNA, and RNA. Recent investigations have revealed a …
View article: <b>Single‐cell RNA Sequencing</b> Contributes to the Treatment of Acute Myeloid Leukaemia With Hematopoietic Stem Cell Transplantation, Chemotherapy, and Immunotherapy
<b>Single‐cell RNA Sequencing</b> Contributes to the Treatment of Acute Myeloid Leukaemia With Hematopoietic Stem Cell Transplantation, Chemotherapy, and Immunotherapy Open
Acute myeloid leukemia (AML) is caused by altered maturation and differentiation of myeloid blasts, as well as transcriptional/epigenetic alterations and impaired apoptosis, all of which lead to excessive proliferation of malignant blood c…
View article: Does outdoor air pollution cause poor semen quality? A systematic review and meta-analysis
Does outdoor air pollution cause poor semen quality? A systematic review and meta-analysis Open
View article: The Microbiota-Gut-Brain Axis in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Narrative Review of an Emerging Field
The Microbiota-Gut-Brain Axis in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Narrative Review of an Emerging Field Open
The intricate relationship between gut microbiota and the brain has emerged as a pivotal area of research, particularly in understanding myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). This complex condition is characterized b…
View article: Recent trends and advances in single-atom nanozymes for the electrochemical and optical sensing of pesticide residues in food and water
Recent trends and advances in single-atom nanozymes for the electrochemical and optical sensing of pesticide residues in food and water Open
Nowadays, single-atom nanozymes (SAzymes) and single-atom catalysts (SACs) have flourished in the field of catalysis owing to their high catalytic performance and exceptional atom utilization efficiency, thereby enhancing biosensing capabi…
View article: Recent advances in catalytic approaches for the synthesis of 3-substituted indoles: mechanisms and strategies
Recent advances in catalytic approaches for the synthesis of 3-substituted indoles: mechanisms and strategies Open
This review highlights recent advancements in the catalytic synthesis of 3-substituted indoles, focusing on improved efficiency, selectivity, and sustainability attained through the use of various catalytic systems and green chemistry appr…
View article: Review of: "Evaluation of Antioxidant Activity and α-Amylase Inhibitory Potential of Melilotus indicus Ethanolic Extract: An In Vitro and In Silico Study"
Review of: "Evaluation of Antioxidant Activity and α-Amylase Inhibitory Potential of Melilotus indicus Ethanolic Extract: An In Vitro and In Silico Study" Open
View article: Pomegranate Juice Attenuates Anti-ulcer in Indomethacin-induced Peptic Ulcer
Pomegranate Juice Attenuates Anti-ulcer in Indomethacin-induced Peptic Ulcer Open
Introduction: Pomegranate (Punica granatum L.) is a well-known fruit that grows in tropical and subtropical areas of the world. In this study, we wanted to find out how pomegranate juice (POMJ) affected rats with gastric ulcers caused by s…
View article: The Local Anesthetic Activity of Lavandula angustifolia and Eugenia caryophyllata Essential Oils
The Local Anesthetic Activity of Lavandula angustifolia and Eugenia caryophyllata Essential Oils Open
Previous studies show that Lavandula angustifolia (lavender) and Eugenia caryophyllata (clove) essential oils can help relieve dental pain. Clove oil and lavender oil were tested as topical anesthetics in this study on rabbits, and their e…
View article: Potential anticancer activity of chemically characterized extract of Olea europaea (Olive) leaves
Potential anticancer activity of chemically characterized extract of Olea europaea (Olive) leaves Open
Olea europaea Linn. (Olive) is considered as essential component of Mediterranean diets. Olive leaves, fruits, and oil are traditionally known for several health benefits including diabetes, cardiac complications, cancer, etc. The objectiv…
View article: Cytostatic Effects of Avocado Oil Using Single-cell Gel Electrophoresis (Comet Assay)
Cytostatic Effects of Avocado Oil Using Single-cell Gel Electrophoresis (Comet Assay) Open
The goal of this paper is to assess the mutagenicand genotoxic potentials of avocado oil made from the fruit pulp of Persea Americana, a member of the Lauraceae family.Michigan Cancer Foundation-7 (MCF-7) cells are used in the 3-4,5 dimeth…
View article: SYBR-Green I fluorescence-based qRT-PCR of clove oil's anticancer, chemical characterization and antidiabetic activities
SYBR-Green I fluorescence-based qRT-PCR of clove oil's anticancer, chemical characterization and antidiabetic activities Open
Syzygium aromaticum is a valuable herbal plant in China, Europe, and Asia.It has been described as a powerful analgesic, anti-inflammatory, antioxidant, antifungal, and antibacterial agent.The goal of this work is to determine the phytocon…
View article: Antibacterial Potential of Bacopa monnieri (L.) Wettst. and Its Bioactive Molecules against Uropathogens—An In Silico Study to Identify Potential Lead Molecule(s) for the Development of New Drugs to Treat Urinary Tract Infections
Antibacterial Potential of Bacopa monnieri (L.) Wettst. and Its Bioactive Molecules against Uropathogens—An In Silico Study to Identify Potential Lead Molecule(s) for the Development of New Drugs to Treat Urinary Tract Infections Open
Urinary tract infections (UTIs) are becoming more common, requiring extensive protection from antimicrobials. The global expansion of multi-drug resistance uropathogens in the past decade emphasizes the necessity of newer antibiotic treatm…
View article: Chemistry, Biosynthesis and Pharmacology of Sarsasapogenin: A Potential Natural Steroid Molecule for New Drug Design, Development and Therapy
Chemistry, Biosynthesis and Pharmacology of Sarsasapogenin: A Potential Natural Steroid Molecule for New Drug Design, Development and Therapy Open
Sarsasapogenin is a natural steroidal sapogenin molecule obtained mainly from Anemarrhena asphodeloides Bunge. Among the various phytosteroids present, sarsasapogenin has emerged as a promising molecule due to the fact of its diverse pharm…
View article: Cobra Venom Neutralization Effect by Hemidesmus indicus Root Extract
Cobra Venom Neutralization Effect by Hemidesmus indicus Root Extract Open
Hemidesmus indicus (Apocynaceae) has been utilized traditionally in the Indian subcontinent for the treatment of snakebites and scorpion stings. It has also several beneficial bioactivities in human beings such as antidiabetic, anti-inflam…
View article: Anti-inflammatory activity of Magic Spice Fruits of Sumac (Rhus coriaria L)
Anti-inflammatory activity of Magic Spice Fruits of Sumac (Rhus coriaria L) Open
The goal of this study is to see how effective Rhus coriaria L (sumac) is at reducing inflammation caused by formalin in mice. The anti-inflammatory efficacy of sumac ethanol extract was tested in mice with formalin-induced paw edema. Anti…
View article: Chemical Composition and Cytotoxic Activity of Pistacia atlantica var. kurdica Fruits
Chemical Composition and Cytotoxic Activity of Pistacia atlantica var. kurdica Fruits Open
Pistacia atlantica var. kurdica (Anacardiaceae) is a major subspecies found in the Kurdistan region of Iraq and has several beneficial bioactivities such as antioxidant, antibacterial, and antiviral. P. atlantica growing in the Kurdistan r…
View article: Withania Somnifera: Correlation of Phytoconstituents with Hypolipidemic and Cardioprotective Activities
Withania Somnifera: Correlation of Phytoconstituents with Hypolipidemic and Cardioprotective Activities Open
Withania somnifera (WS) (Dunal) or Ashwagandha is a well-known hypolipidemic herb and antioxidant. In this study, 75% ethanolic extract of WS is attempted to evaluate the cardioprotective activity of isoproterenol-induced cardiotoxicity an…
View article: Analgesic and Anti-inflammatory Activity of Withania somnifera Root Extract
Analgesic and Anti-inflammatory Activity of Withania somnifera Root Extract Open
The anti-inflammatory and analgesic properties of the 85 % methanolic extract of Withania somnifera (WS) root was investigated and the anti-inflammatory effect was compared with the standard drug indomethacin. Analgesic activity was carrie…
View article: Chemical Characterization and Antidiabetic Activity of Essential Oils from Pelargonium graveolens Leaves
Chemical Characterization and Antidiabetic Activity of Essential Oils from Pelargonium graveolens Leaves Open
Pelargonium graveolens (Geranium) is a source of the finest quality of fragrance and its essential oils are used as antibacterial, and antifungal agents. The aim of the current research is to determine chemical constituents in the essentia…
View article: Characterization of Chemical Compounds in Volatile Oil and Ethyl Acetate Extract of Lavandula angustifolia by GC-MS
Characterization of Chemical Compounds in Volatile Oil and Ethyl Acetate Extract of Lavandula angustifolia by GC-MS Open
Lavandula angustifolia is an important aromatic plant and rich source of linalool. L. angustifolia and its bioactive compounds have been reported to possess several bioactivities such as antioxidant, antifungal, antibacterial and antidiabe…
View article: Evaluation of Genotoxic effects of a Hydro-alcoholic extract of flowers of Nargis (Narcissus Tazetta L.)
Evaluation of Genotoxic effects of a Hydro-alcoholic extract of flowers of Nargis (Narcissus Tazetta L.) Open
The goal of this study was to determine the genotoxic potential of a hydroalcoholic extract of Nargis flowers (Narcissus Tazetta L.). The genotoxicity potential of standardized hydroalcoholic extract of Narcissus Tazetta L at different con…
View article: Silybum marianum (Milk Thistle): Review on Its chemistry, morphology, ethno medical uses, phytochemistry and pharmacological activities
Silybum marianum (Milk Thistle): Review on Its chemistry, morphology, ethno medical uses, phytochemistry and pharmacological activities Open
The oldest remedies identified to mankind are herbal medicines. India is recognized worldwide for its Ayurvedic treatment. India has rich history of using many plants for medicinal purposes. Remedial plants are cooperating extremely dynami…
View article: PHYTOCHEMICAL ANALYSIS OF DIFFERENT FRACTIONS OF TERMINALIA ARJUNA BARK BY GC-MS
PHYTOCHEMICAL ANALYSIS OF DIFFERENT FRACTIONS OF TERMINALIA ARJUNA BARK BY GC-MS Open
Traditionally Terminalia arjuna Roxb.(T.arjuna) is being used widely to cure various diseases like cardiovascular diseases, liver diseases, and cancer etc.The aim of the present study is to phytochemical analysis of petroleum ether, ethyl …